Alterations in T-Cell Transcription Factors and Cytokine Gene Expression in Late-Onset Alzheimer’s Disease

Autor: Mina Makvand, Arezoo Campbell, Seyed Kazem Malakouti, Leila Kamalzadeh, Ghasem Ahangari, Masoud Neshan

Publikováno v: Journal of Alzheimer's Disease. 85:645-665

Background: Late-onset Alzheimer’s disease (LOAD) is associated with many environmental and genetic factors. The effect of systemic inflammation on the pathogenesis of neurodegenerative diseases such as AD has been strongly suggested. T helper cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca78bb12b2c74ce90d1f0098a3c587c
https://doi.org/10.3233/jad-210480

The Effectiveness of Methadone Maintenance Therapy (MMT) on Drug Tolerance, Mediated by Receptor Signaling, Signal Transduction and Intracellular Transport

Autor: Mina Makvand, Seyed Davood Mirtorabi, Gholamreza Hassanzadeh, Arezoo Campbell, Ghasem Ahangari

Introduction: In chronic drug abuse, opioidergic, dopaminergic signaling, and endocytosis are implicated in neural circuit disruption. We evaluate the impact of Methadone Maintenance Therapy (MMT) on opioid addiction.Method: The expression of dopamin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2111d7a56ae2aa6561a40e2025d51926
https://doi.org/10.21203/rs.3.rs-1562550/v1

Distinctive cellular response to aluminum based adjuvants

Autor: Krisha Hidalgo, Isaac Nies, Stephen C. Bondy, Arezoo Campbell

Aluminum-based adjuvants (ABAs) are used in human vaccines to enhance the magnitude of protective immune responses elicited against specific pathogens. One hypothesis is that stress signals released by aluminum-exposed necrotic cells play a role in m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19203da742da9eec29702bcd1efc1f5
https://escholarship.org/uc/item/7v86t1cb

Mechanisms Underlying Tumor Suppressive Properties of Melatonin

Autor: Stephen C. Bondy, Arezoo Campbell

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 8, p 2205 (2018)
International Journal of Molecular Sciences
Bondy, SC; & Campbell, A. (2018). Mechanisms Underlying Tumor Suppressive Properties of Melatonin. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(8). doi: 10.3390/ijms19082205. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4zc711jb

There is considerable evidence that melatonin may be of use in the prevention and treatment of cancer. This manuscript will review some of the human, animal and cellular studies that provide evidence that melatonin has oncostatic properties. Confirma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9698c4b546ebb9d57cf3481bbddddc
http://www.mdpi.com/1422-0067/19/8/2205

Water Quality and Brain Function

Autor: Arezoo Campbell, Stephen C. Bondy

Publikováno v: International Journal of Environmental Research and Public Health, Vol 15, Iss 1, p 2 (2017)
International Journal of Environmental Research and Public Health
Bondy, SC; & Campbell, A. (2018). Water Quality and Brain Function. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 15(1). doi: 10.3390/ijerph15010002. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5sm0956r

In the United States, regulations are in place to ensure the quality of drinking water. Such precautions are intended to safeguard the health of the population. However, regulatory guidelines may at times fail to achieve their purpose. This may be du

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b870893eef0171e7bc17a1e5ad5fc9
https://www.mdpi.com/1660-4601/15/1/2