Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Arevat Kostanian"'
Autor:
Arevat Kostanian, Jutta Walstab, Heinz Bönisch, Sandra Combrink, Michael Brüss, Manfred Göthert, Martin Barann
Publikováno v:
Pharmacological Reports. 61:785-797
The present study aimed at examining the function and pharmacological properties of the naturally occurring Arg344His variant of the human 5-HT(3A) receptor, identified in a schizophrenic patient. In intact human embryonic kidney (HEK) 293 cells expr
Publikováno v:
Neurochemistry International. 47:196-203
In the present study on transfected human embryonic kidney (HEK)293 cells, we aimed at establishing whether expression of the naturally occurring Thr 92 Lys variation of the G s -coupled h5-HT 7(a) receptor leads to changes of ligand binding properti
Autor:
Arevat Kostanian, Manfred Göthert, Martin Barann, Sandra Combrink, Delia Kurzwelly, Heinz Bönisch, Michael Brüss
Publikováno v:
Pharmacogenetics. 14:165-172
The 5-HT 3A receptor, a ligand-gated ion channel, is involved in pain pathways, nausea and emesis, and irritable bowel syndrome, and may play a role in the pathogenesis of psychiatric diseases such as schizophrenia and depression. Recently, a natural
Publikováno v:
Pharmacogenetics and genomics. 15(4)
The present study in transfected HEK293 cells aimed to investigate whether the pharmacological and/or transductional properties of the naturally occurring Arg219Leu variant (VAR) in the third intracellular loop of the h5-HT1A receptor differ from tho
Publikováno v:
Neurochemistry international. 47(3)
In the present study on transfected human embryonic kidney (HEK)293 cells, we aimed at establishing whether expression of the naturally occurring Thr92Lys variation of the Gs-coupled h5-HT7(a) receptor leads to changes of ligand binding properties, o