Development of a rapid HPLC-fluorescence method for monitoring warfarin metabolites formation: In vitro studies for evaluating the effect of piperine on warfarin metabolism and plasma coagulation

Autor: Zayed, Aref L., Hadieh, Mohammad, Al Hroot, Jomana, Hameedat, Fatima, Jaber, Sana'a A.

Publikováno v: In Heliyon 30 May 2024 10(10)

Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking

Autor: Suaad A. Audat, Nizar A. Al-Shar’i, Buthina A. Al-Oudat, Amanda Bryant-Friedrich, Mel F. Bedi, Aref L. Zayed, Qosay A. Al-Balas

Publikováno v: Molecules, Vol 25, Iss 12, p 2871 (2020)

Leukotriene B4 (LTB4) is a potent, proinflammatory lipid mediator implicated in the pathologies of an array of inflammatory diseases and cancer. The biosynthesis of LTB4 is regulated by the leukotriene A4 hydrolase (LTA4H). Compounds capable of limit

Externí odkaz: https://doaj.org/article/ed23270042104febb9ac5394ef5b2524

Low Molecular Weight Chitosan-Coated PLGA Nanoparticles for Pulmonary Delivery of Tobramycin for Cystic Fibrosis

Autor: Nusaiba K. Al-Nemrawi, Nid’’A H. Alshraiedeh, Aref L. Zayed, Bashar M. Altaani

Publikováno v: Pharmaceuticals, Vol 11, Iss 1, p 28 (2018)

(1) Background: Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) loaded with Tobramycin were prepared using a solvent-evaporation method. (2) Methods: The NPs were coated with low molecular weight chitosan (LMWC) to enhance the mucoadhesivene

Externí odkaz: https://doaj.org/article/330d9960a130468782e5ef11a47ec030

The phers R package: using phenotype risk scores based on electronic health records to study Mendelian disease and rare genetic variants.

Autor: Aref L; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Bastarache L; Program in Chemical and Physical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA., Hughey JJ; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.; Program in Chemical and Physical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

Publikováno v: Bioinformatics (Oxford, England) [Bioinformatics] 2022 Oct 31; Vol. 38 (21), pp. 4972-4974.

Low Molecular Weight Chitosan-Coated PLGA Nanoparticles for Pulmonary Delivery of Tobramycin for Cystic Fibrosis.

Autor: Al-Nemrawi, Nusaiba K., Alshraiedeh, Nid’’A H., Zayed, Aref L., Altaani, Bashar M.

Publikováno v: Pharmaceuticals (14248247); Mar2018, Vol. 11 Issue 1, p28, 13p