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Inhibitors of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (Statins) Suppress Proliferation and Motility of Human CD4+ T Lymphocytes in Culture

Autor: Aref'eva Ti, N.V. Radyukhina, A Yu Filatova, N. Yu. Ruleva

Publikováno v: Bulletin of Experimental Biology and Medicine. 172:137-142

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) along with their blood lipid-lowering effect exhibit anti-inflammatory and immunomodulatory activity. We studied the effects of long-term (72-h or longer) exposure of human T lympho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2f8041ec2b0babefabf066df2cdea2d
https://doi.org/10.1007/s10517-021-05350-w

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Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) suppress human CD4+ T-lymphocytes proliferation and motility in vitro

Autor: N. Yu. Ruleva, A Yu Filatova, Aref'eva Ti, N.V. Radyukhina

Publikováno v: Bulletin of Experimental Biology and Medicine. 172:162-167

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::735e2a8bd7e966b37b45b7b9658f5dae
https://doi.org/10.47056/0365-9615-2021-172-8-162-167

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Atherosclerosis of brachiocephalic arteries and arterial stiffness in patients with breast cancer

Autor: E A Pylaeva, Olga I. Afanasieva, A M Shchinova, S. V. Gavryushina, M. V. Vitsenya, A.B. Pestova, E.A. Klesareva, A V Potekhina, Aref'eva Ti, M B Stenina, M A Frolova, Ageev Ft, A Yu Filatova

Publikováno v: Kardiologiia. 59:43-52

Cardiovascular toxicity is one of the important problems of clinical oncology. Atherosclerosis progression was demonstrated in patients with cancer and chemotherapy.Te aim– to evaluate the vascular wall characteristics and to determine the predicto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7d2d9608b9d52e9b529c8d2fea202d0
https://doi.org/10.18087/cardio.2585

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Low Blood Content of IL-10-Producing CD4+ T Cells as a Risk Factor for Progression of Coronary Atherosclerosis

Autor: E.A. Noeva, S I Provatorov, Aref'eva Ti, V P Masenko, A Yu Filatova, N.V. Radyukhina, E A Pylaeva, A V Potekhina, A M Shchinova, E.A. Klesareva, O I Afanas'eva, N. Yu. Ruleva

Publikováno v: Bulletin of Experimental Biology and Medicine. 166:330-333

In a 2-year prospective study, prognostic significance of the blood content of IL-10-producing CD4+ T lymphocytes for progression of coronary artery atherosclerosis was assessed. Patients with verified stable angina (n=36) admitted for scheduled coro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e9e227760675d1bd12d2aaf350170be
https://doi.org/10.1007/s10517-019-04344-z

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Inhibitors of 3-Hydroxy-3-Methylglutaryl Coenzyme a Reductase (Statins) Suppress Differentiation and Reduce LPS/IFNγ-Induced Cytokine Production in Human Monocyte/Macrophage Culture

Autor: E S Zubkova, N.V. Radyukhina, A Yu Filatova, N. Yu. Ruleva, Aref'eva Ti

Publikováno v: Bulletin of experimental biology and medicine. 170(2)

We examined the effects of 72-h exposure to atorvastatin and rosuvastatin in concentrations of 2-10 nM on the cytokine expression in LPS/IFNγ-activated monocyte/macrophages derived from peripheral blood monocytes of healthy donors by culturing in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7230a8e95489e40e68380379228d81
https://pubmed.ncbi.nlm.nih.gov/33263856

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Effects of synthetic monocyte chemotactic protein-1 fragment 65-76 on neointima formation after carotid artery balloon injury in rats

Autor: N. B. Kukhtina, T. L. Krasnikova, V. O. Sokolov, Zh. D. Bespalova, Maria Sidorova, P. P. Bashtrykov, Aref'eva Ti

Publikováno v: Neuroscience and behavioral physiology. 39(2)

The effects of the synthetic monocyte chemotactic protein-1 (MCP-1) peptide fragment 65-76 (peptide X) on the development of neointima after balloon injury to the carotid artery were studied. The agent was given i.m. at a dose of 33 microg/kg once da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41afb73fa2a864f11a1f75c07a749539
https://pubmed.ncbi.nlm.nih.gov/19140000

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Inhibition of migration of monocytes and granulocytes in vivo by the peptide corresponding to sequence 65-76 of monocyte chemotactic protein-1 (MCP-1)

Autor: V. V. Pozdeev, Aref'eva Ti, E. I. Chazov, V. B. Sergienko, M. G. Melekhov, B. M. Mart’yanov, Maria Sidorova, T. L. Bushueva, Zh. D. Bespalova, A. S. Molokoedov, T. L. Krasnikova, T. E. Gvozdik, N. B. Kukhtina

Publikováno v: Doklady. Biochemistry and biophysics. 411

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d9b7ca4fe08856f51461e75b617aed
https://pubmed.ncbi.nlm.nih.gov/17396576

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Peptide fragment 66-77 of monocyte chemoattractant protein 1 and its retro-enantio analogue inhibits the migration of cells in vitro and in vivo

Autor: N. B. Kukhtina, V. N. Bushuev, A. S. Molokoedov, T. L. Krasnikova, Aref'eva Ti, A. A. Az’muko, M. G. Melekhov, Maria Sidorova, Zh. D. Bespalova

Publikováno v: Scopus-Elsevier

The retro-enantio-analogue of peptide 66–77 of the chemokine MCP-1 and two hexapeptide fragments 66–71 and 72–77 of the C-terminal sequence of this protein were synthesized using the Fmoc strategy of solid phase peptide synthesis. The effect of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295fcf88826c4f39bf3df7e78fae1712
http://www.scopus.com/inward/record.url?eid=2-s2.0-33744536561&partnerID=MN8TOARS

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Akademický článek

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