Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Arden Perkins"'
Autor:
Arden Perkins, Dan A. Tudorica, Raphael D. Teixeira, Tilman Schirmer, Lindsay Zumwalt, O. Maduka Ogba, C. Keith Cassidy, Phillip J. Stansfeld, Karen Guillemin
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Immune cells are well equipped to eliminate invading bacteria, and one of their primary tools is the synthesis of bleach, hypochlorous acid (HOCl), the same chemical used as a household disinfectant. In this work, we present findings showing that man
Externí odkaz:
https://doaj.org/article/552441f439374f9fbe0178df8f79fafe
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000395 (2019)
The gastric pathogen Helicobacter pylori requires a noncanonical cytosolic chemoreceptor transducer-like protein D (TlpD) for efficient colonization of the mammalian stomach. Here, we reconstituted a complete chemotransduction signaling complex in vi
Externí odkaz:
https://doaj.org/article/3d1a943f22234782b55e69b10382f708
Autor:
Annah S Rolig, Emily Goers Sweeney, Lila E Kaye, Michael D DeSantis, Arden Perkins, Allison V Banse, M Kristina Hamilton, Karen Guillemin
Publikováno v:
eLife, Vol 7 (2018)
Stable mutualism between a host and its resident bacteria requires a moderated immune response to control bacterial population size without eliciting excessive inflammation that could harm both partners. Little is known about the specific molecular m
Externí odkaz:
https://doaj.org/article/a485b9400d2a40598196c1195f2cc15f
Autor:
Arden Perkins, Jessica L. Phillips, Nancy I. Kerkvliet, Robert L. Tanguay, Gary H. Perdew, Siva K. Kolluri, William H. Bisson
Publikováno v:
Biology, Vol 3, Iss 4, Pp 645-669 (2014)
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that regulates the expression of a diverse group of genes. Exogenous AHR ligands include the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), which is
Externí odkaz:
https://doaj.org/article/f54bb2bd91a74ae7a99b7977add02010
Autor:
Emily Goers Sweeney, Emily Ma, Nicolas L. Fernandez, S. James Remington, Arden Perkins, Catherine D. Robinson, T. Jarrod Smith, Julia Ngo, Karen Guillemin, Brendan J. M. Bohannan, Christopher M. Waters
Publikováno v:
Cell Host Microbe
Animal microbiomes are assembled predominantly from environmental microbes, yet the mechanisms by which individual symbionts regulate their transmission into hosts remain underexplored. By tracking the experimental evolution of Aeromonas veronii in g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb5509bdf9af4e51e329eebdfb85f68
https://europepmc.org/articles/PMC8522913/
https://europepmc.org/articles/PMC8522913/
Autor:
Arden Perkins, Lindsey O’Neal
Publikováno v:
Trends Microbiol
Rural individuals are underrepresented in science at all levels. The disenfranchisement of rural people in science and research foments a cultural divide between rural America and the scientific community. Science can improve inclusion of rural indiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a24ae0df5f10216c5ad9db6140f9ea
https://pubmed.ncbi.nlm.nih.gov/34274196
https://pubmed.ncbi.nlm.nih.gov/34274196
Publikováno v:
Chemphyschem : a European journal of chemical physics and physical chemistry. 21(21)
Quantum mechanical calculations reveal the preferred mechanism and origins of chemoselectivity for HOCl-mediated oxidation of zinc-bound thiolates implicated in bacterial redox sensing. Distortion/interaction models show that minimizing geometric dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fedb4111eae4c401333b05426a3de9
https://pubmed.ncbi.nlm.nih.gov/32915482
https://pubmed.ncbi.nlm.nih.gov/32915482
Many proteins interact with short linear regions of target proteins. For some proteins, however, it is difficult to identify a well-defined sequence motif that defines its target peptides. To overcome this difficulty, we used supervised machine learn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21fbe5fbdae3fecba76134561a58af6c
https://doi.org/10.1101/2020.06.02.131086
https://doi.org/10.1101/2020.06.02.131086
Publikováno v:
Protein Sci
Many proteins interact with short linear regions of target proteins. For some proteins, however, it is difficult to identify a well-defined sequence motif that defines its target peptides. To overcome this difficulty, we used supervised machine learn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dde40bc1a55d81e8750488d8301d796
https://pubmed.ncbi.nlm.nih.gov/32979254
https://pubmed.ncbi.nlm.nih.gov/32979254
Publikováno v:
Protein Science. 27:1961-1968
Bacteria use chemoreceptor proteins to sense and navigate their chemical environments. The most common class of chemoreceptors are transmembrane proteins that sense chemical cues through binding of a small-molecule ligand to a periplasmic domain, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d1c15869e887fed08edcc6492a48255
https://doi.org/10.1002/pro.3503
https://doi.org/10.1002/pro.3503