Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease

Autor: Frederic Brosseron, Anne Maass, Luca Kleineidam, Kishore Aravind Ravichandran, Pablo García González, Róisín M. McManus, Christina Ising, Francesco Santarelli, Carl-Christian Kolbe, Lisa M. Häsler, Steffen Wolfsgruber, Marta Marquié, Mercè Boada, Adelina Orellana, Itziar de Rojas, Sandra Röske, Oliver Peters, Nicoleta-Carmen Cosma, Arda Cetindag, Xiao Wang, Josef Priller, Eike J. Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Björn H. Schott, Katharina Bürger, Daniel Janowitz, Martin Dichgans, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H. Munk, Emrah Düzel, Renat Yakupov, Laura Dobisch, Coraline D. Metzger, Wenzel Glanz, Michael Ewers, Peter Dechent, John Dylan Haynes, Klaus Scheffler, Nina Roy, Ayda Rostamzadeh, Charlotte E. Teunissen, Natalie L. Marchant, Annika Spottke, Mathias Jucker, Eicke Latz, Michael Wagner, David Mengel, Matthis Synofzik, Frank Jessen, Alfredo Ramirez, Agustín Ruiz, Michael T. Heneka

Publikováno v: the DELCODE study group 2022, ' Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease ', Neuron, vol. 110, no. 6, pp. 1009-1022.e4 . https://doi.org/10.1016/j.neuron.2021.12.016
Neuron, 110(6), 1009-1022.e4. Cell Press
Neuron 110(6), 1009-1022.e4 (2022). doi:10.1016/j.neuron.2021.12.016

There is an urgent need to improve the understanding of neuroinflammation in Alzheimer's disease (AD). We analyzed cerebrospinal fluid inflammatory biomarker correlations to brain structural volume and longitudinal cognitive outcomes in the DELCODE s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41ef513202d55323e4fa7d6c6fae0e9
https://research.vumc.nl/en/publications/7b3bd725-fd82-4214-85cb-1b6558b53b1c