Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Arda, Mizrak"'
Autor:
Arda Mizrak, David O. Morgan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Activation of APC/C depends on transient interactions with an activator subunit. Here, the authors show that cellular polyanions trigger APC/C-activator dissociation and that high-affinity substrates block this effect, suggesting that substrate avail
Externí odkaz:
https://doaj.org/article/869fdb2adcb8456499a4ef87da848460
Autor:
Fernando Meza Gutierrez, Deniz Simsek, Arda Mizrak, Adam Deutschbauer, Hannes Braberg, Jeffrey Johnson, Jiewei Xu, Michael Shales, Michelle Nguyen, Raquel Tamse-Kuehn, Curt Palm, Lars M Steinmetz, Nevan J Krogan, David P Toczyski
Publikováno v:
eLife, Vol 7 (2018)
Although polyubiquitin chains linked through all lysines of ubiquitin exist, specific functions are well-established only for lysine-48 and lysine-63 linkages in Saccharomyces cerevisiae. To uncover pathways regulated by distinct linkages, genetic in
Externí odkaz:
https://doaj.org/article/f07665d4c7984c8e8770d5baaa41a25f
Autor:
Xandra O. Breakefield, Gary J. Brenner, Nurten Saydam, Anna M. Krichevsky, Robert M. Stephens, Ming Yi, Anat O. Stemmer-Rachamimov, Gokhan Baris Ozdener, Arda Mizrak, Thomas Würdinger, Ozlem Senol, Okay Saydam
Supplementary Table 1 from miRNA-7 Attenuation in Schwannoma Tumors Stimulates Growth by Upregulating Three Oncogenic Signaling Pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81772cc2daa18d128b158232ebbe94a0
https://doi.org/10.1158/0008-5472.22388858
https://doi.org/10.1158/0008-5472.22388858
Autor:
Xandra O. Breakefield, Gary J. Brenner, Nurten Saydam, Anna M. Krichevsky, Robert M. Stephens, Ming Yi, Anat O. Stemmer-Rachamimov, Gokhan Baris Ozdener, Arda Mizrak, Thomas Würdinger, Ozlem Senol, Okay Saydam
Supplementary Figures 1-5 from miRNA-7 Attenuation in Schwannoma Tumors Stimulates Growth by Upregulating Three Oncogenic Signaling Pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c69fae4fc5551ffad5b0dbb8b6116a
https://doi.org/10.1158/0008-5472.22388864.v1
https://doi.org/10.1158/0008-5472.22388864.v1
Autor:
Jiunn Song, Marcelo Cicconet, Robert V. Farese, Arda Mizrak, Tobias C. Walther, Zon Weng Lai, Chieh-Han Lu, Chia-Wei Lee, Stephanie E. Mohr
Publikováno v:
Nature cell biology. 24(9)
SUMMARYPathways localizing proteins to their sites of action within a cell are essential for eukaryotic cell organization and function. Although mechanisms of protein targeting to many organelles have been defined, little is known about how proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b1c7f62519af1f3bef7285892ce147
https://pubmed.ncbi.nlm.nih.gov/36050470
https://pubmed.ncbi.nlm.nih.gov/36050470
Publikováno v:
Molecular Biology of the Cell
Molecular biology of the cell, vol 31, iss 7
Molecular biology of the cell, vol 31, iss 7
Mitochondrial function depends crucially on the maintenance of multiple mitochondrial DNA (mtDNA) copies. Surprisingly, the cellular mechanisms regulating mtDNA copy number remain poorly understood. Through a systematic high-throughput approach in Sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9acff954bdc3fa35d6a52d41528791
Autor:
Mehmet Fatih Bolukbasi, Arda Mizrak, Gokhan Baris Ozdener, Sibylle Madlener, Thomas Ströbel, Erdogan Pekcan Erkan, Jian-Bing Fan, Xandra O Breakefield, Okay Saydam
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Despite intensive studies, the molecular mechanisms by which the genetic materials are uploaded into microvesicles (MVs) are still unknown. This is the first study describing a zipcode-like 25 nucleotide (nt) sequence in the 3′-untranslated region
Externí odkaz:
https://doaj.org/article/f76e53ed5a254ac0a0271d8823293e50
Autor:
Liang Qin, Dimitrius Santiago P. S. F. Guimarães, Hana Maldivita Tambrin, Mark C. Hall, David O. Morgan, Arda Mizrak
Publikováno v:
J Biol Chem
The anaphase-promoting complex/cyclosome (APC/C) is a large, multisubunit ubiquitin ligase involved in regulation of cell division. APC/C substrate specificity arises from binding of short degron motifs in its substrates to transient activator subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a18892a1511d70b69673435ac46c206
https://europepmc.org/articles/PMC6873173/
https://europepmc.org/articles/PMC6873173/
Publikováno v:
Molecular Biology of the Cell
Mitochondrial function depends crucially on the maintenance of multiple mitochondrial DNA (mtDNA) copies. Surprisingly, the cellular mechanisms regulating mtDNA copy number remain poorly understood. Through a systematic high-throughput approach in Sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cce573b33202dc87ba3d521fb7b4d476
https://pubmed.ncbi.nlm.nih.gov/31532710
https://pubmed.ncbi.nlm.nih.gov/31532710
Autor:
Adam M. Deutschbauer, Jiewei Xu, David P. Toczyski, Michelle Nguyen, Raquel Tamse-Kuehn, Jeffrey R. Johnson, Nevan J. Krogan, Hannes Braberg, Fernando Meza Gutierrez, Curt Palm, Arda Mizrak, Michael Shales, Lars M. Steinmetz, Deniz Simsek
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Although polyubiquitin chains linked through all lysines of ubiquitin exist, specific functions are well-established only for lysine-48 and lysine-63 linkages in Saccharomyces cerevisiae. To uncover pathways regulated by distinct linkages, genetic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074fa1ae5c0c86cf766c6a43f6eef014
https://elifesciences.org/articles/42955
https://elifesciences.org/articles/42955