Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Arco Bast"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 4, p e1011468 (2024)
Neurons in the cerebral cortex receive thousands of synaptic inputs per second from thousands of presynaptic neurons. How the dendritic location of inputs, their timing, strength, and presynaptic origin, in conjunction with complex dendritic physiolo
Externí odkaz:
https://doaj.org/article/ce3cff420a6047cf8d74850cc27144c2
Autor:
Christiaan P. J. de Kock, Jean Pie, Anton W. Pieneman, Rebecca A. Mease, Arco Bast, Jason M. Guest, Marcel Oberlaender, Huibert D. Mansvelder, Bert Sakmann
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
In order to investigate the information encoded by spiking activity in different neuronal cell types in the primary somatosensory cortex, de Kock et al performed electrophysiological recordings in untrained rats. They demonstrated that an increase in
Externí odkaz:
https://doaj.org/article/545cc6b7f83a4daf9de820113342a7e0
Autor:
Arco Bast, Marcel Oberlaender
The mammalian brain has an enormous demand for energy, which is thought to impose strong selective pressure by which the neurons evolve in ways that ensure robust function at minimal energy cost. However, which principles drive the ion channel distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::035dbc59ed2d2beb3077729bf9aee552
https://doi.org/10.1101/2021.12.11.472235
https://doi.org/10.1101/2021.12.11.472235
Circuit-selective cell-autonomous regulation of inhibition in pyramidal neurons by Ste20-like kinase
Autor:
Pedro Royero, Anne Quatraccioni, Rieke Früngel, Mariella Hurtado Silva, Arco Bast, Thomas Ulas, Marc Beyer, Thoralf Opitz, Joachim L. Schultze, Mark E. Graham, Marcel Oberlaender, Albert Becker, Susanne Schoch, Heinz Beck
Publikováno v:
Cell reports 41(10), 111757 (2022). doi:10.1016/j.celrep.2022.111757
Cell Reports
Cell Reports
Maintaining an appropriate balance between excitation and inhibition is critical for neuronal information processing. Cortical neurons can cell-autonomously adjust the inhibition they receive to individual levels of excitatory input, but the underlyi
Perception is causally linked to a calcium-dependent spiking mechanism that is built into the distal dendrites of layer 5 pyramidal tract neurons – the major output cell type of the cerebral cortex. It is yet unclear which circuits activate this ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2e69a270b6be9c447203ff9932b3cff
https://doi.org/10.1101/2021.10.21.465325
https://doi.org/10.1101/2021.10.21.465325
Autor:
Huibert D. Mansvelder, Christiaan P. J. de Kock, Rebecca A. Mease, Jean L Pie, Marcel Oberlaender, Anton W. Pieneman, Bert Sakmann, JM Guest, Arco Bast
Publikováno v:
Communications biology, 4(1):709. Nature Research
Communications Biology
de Kock, C P J, Pie, J, Pieneman, A W, Mease, R A, Bast, A, Guest, J M, Oberlaender, M, Mansvelder, H D & Sakmann, B 2021, ' High-frequency burst spiking in layer 5 thick-tufted pyramids of rat primary somatosensory cortex encodes exploratory touch ', Communications biology, vol. 4, no. 1, 709 . https://doi.org/10.1038/s42003-021-02241-8
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
de Kock, C P J, Pie, J, Pieneman, A W, Mease, R A, Bast, A, Guest, J M, Oberlaender, M, Mansvelder, H D & Sakmann, B 2021, ' High-frequency burst spiking in layer 5 thick-tufted pyramids of rat primary somatosensory cortex encodes exploratory touch ', Communications biology, vol. 4, no. 1, 709 . https://doi.org/10.1038/s42003-021-02241-8
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Diversity of cell-types that collectively shape the cortical microcircuit ensures the necessary computational richness to orchestrate a wide variety of behaviors. The information content embedded in spiking activity of identified cell-types remain un
Autor:
Arco Bast, Marcel Oberlaender, Robert Egger, Luis F. Messore, Daniel Udvary, Suman Das, Rajeevan T. Narayanan, JM Guest, Christiaan P. J. de Kock
Publikováno v:
Egger, R, Narayanan, R T, Guest, J M, Bast, A, Udvary, D, Messore, L F, Das, S, de Kock, C P J & Oberlaender, M 2020, ' Cortical Output Is Gated by Horizontally Projecting Neurons in the Deep Layers ', Neuron, vol. 105, no. 1, pp. 122-137.e8 . https://doi.org/10.1016/j.neuron.2019.10.011
Neuron
Neuron, 105(1), 122-137.e8. Cell Press
Neuron
Neuron, 105(1), 122-137.e8. Cell Press
Summary Pyramidal tract neurons (PTs) represent the major output cell type of the mammalian neocortex. Here, we report the origins of the PTs’ ability to respond to a broad range of stimuli with onset latencies that rival or even precede those of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e24713792377c2c3a12b5be08aa61e
https://hdl.handle.net/1871.1/4f224aac-92eb-4770-b09e-06aa9ec15452
https://hdl.handle.net/1871.1/4f224aac-92eb-4770-b09e-06aa9ec15452
Autor:
JM Guest, Rajeevan T. Narayanan, Daniel Udvary, Arco Bast, S. Das, Christiaan P. J. de Kock, Robert Egger, Marcel Oberlaender
Publikováno v:
bioRxiv : the preprint server for biology
Sensory information enters the neocortex via thalamocortical axons that define the major ‘input’ layer 4. The same thalamocortical axons, however, additionally innervate the deep ‘output’ layers 5/6. How such bistratification impacts cortical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a0414979054ae6b968113636b779d3
https://doi.org/10.1101/524298
https://doi.org/10.1101/524298