Zobrazeno 1 - 10
of 973
pro vyhledávání: '"Architecture domain"'
Publikováno v:
Journal of Molecular Evolution. 89:665-677
Plant hormone cytokinins are important regulators of plant development, response to environmental stresses and interplay with other plant hormones. Cytokinin dehydrogenases (CKXs) are proteins responsible for the irreversible break-down of cytokinins
Autor:
Erdem Tabdanov, Venkat R. Chirasani, Nikolay V. Dokholyan, Yashavantha L. Vishweshwaraiah, Jiaxing Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Advances in protein design have brought us within reach of developing a nanoscale programming language, in which molecules serve as operands and their conformational states function as logic gates with precise input and output behaviors. Combining th
Publikováno v:
Nature Plants. 7:1389-1396
MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes by directly binding to their mRNAs. In animals, pri-miRNAs are cleaved by Drosha to generate pre-miRNAs, which are subsequently cleaved by Dicer to generate matu
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 89:1473-1488
In Gram-negative bacteria, the maintenance of lipid asymmetry (Mla) system is involved in the transport of phospholipids between the inner (IM) and outer membrane. The Mla system utilizes a unique IM-associated periplasmic solute-binding protein, Mla
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-14 (2021)
BMC Genomics
BMC Genomics
BackgroundFibrillar adhesins are long multidomain proteins attached at the cell surface and composed of at least one adhesive domain and multiple tandemly repeated domains, which build an elongated stalk that projects the adhesive domain beyond the b
Publikováno v:
Protein Sci
Fusion transcription factors generated by genomic translocations are common drivers of several types of cancers including sarcomas and leukemias. Oncofusions of the FET (FUS, EWSR1, and TAF15) family proteins result from the fusion of the prion-like
Autor:
Volodymyr Dvornyk, Qiming Mei
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
The circadian system of cyanobacteria is built upon a central oscillator consisting of three genes, kaiA, kaiB, and kaiC. The KaiA protein plays a key role in phosphorylation/dephosphorylation cycles of KaiC, which occur over the 24-h period. We cond
Autor:
Kazue Terasawa, Takanori Iwata, Yuri Tomabechi, Tetsuro Watabe, Mutsuko Kukimoto-Niino, Yuta Ikami, Shigeyuki Yokoyama, Kazumasa Ohtake, Toshihide Kobayashi, Miki Hara-Yokoyama, Kensaku Sakamoto, Mikako Shirouzu, Jun-Lin Guan, Seisuke Kusano, Yuji Kato
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
LAMP1 (lysosomal-associated membrane protein 1) and LAMP2 are the most abundant protein components of lysosome membranes. Both LAMPs have common structures consisting of a large lumenal domain composed of two domains (N-domain and C-domain, which are
Publikováno v:
Current Genomics
Background: The two-component signaling (TCS) system is an important signal transduction machinery in prokaryotes and eukaryotes, excluding animals, that uses a protein phosphorylation mechanism for signal transmission. Conclusion: Prokaryotes have a
Autor:
Junichi Takagi, Kei Suzuki, Masamichi Nagae, Terukazu Nogi, Takao Kohno, Norihisa Yasui, Mitsuharu Hattori
Publikováno v:
The Journal of Biochemistry. 169:555-564
The large, secreted glycoprotein reelin regulates embryonic brain development as well as adult brain functions. Although reelin binds to its receptors via its central part, the N-terminal region directs multimer formation and is critical for efficien