Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Archita Ghoshal"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The gap junction (GJ) protein connexin-43 (Cx43) is considered as a tumour suppressor protein for its role in reversing the phenotype of the cancer cells. In this study, we exploited the antitumor property of Cx43 in conjunction with the art
Externí odkaz:
https://doaj.org/article/18312af788fa441992ba482539b4c824
Autor:
Love Panchariya, Kirtishila Sonkar, Jitendra K. Thakur, Wajahat Ali Khan, Archita Ghoshal, Dileep Kumar Verma, Ankit Kumar, A. Arockiasamy, Mohd Azeem Khan, Rajkumar Halder, Sibasis Sahoo, Souvik Maiti, Abdul Hasan, Sujatha Sunil, Niyati Jain, Amit Kumar Mohapatra, Shubhashis Das, Ranjan Kumar Nanda, Shobhan Kuila
Publikováno v:
Chemical Communications. 57:10083-10086
Zinc deficiency is linked to poor prognosis in COVID-19 patients while clinical trials with zinc demonstrate better clinical outcomes. The molecular targets and mechanistic details of the anti-coronaviral activity of zinc remain obscure. We show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f7386c1a2a9d6f3d52dc880ca956226
https://doi.org/10.1039/d1cc03563k
https://doi.org/10.1039/d1cc03563k
Autor:
Thomas Abraham, Irina Elcheva, Vladimir S. Spiegelman, Lucas Campos de Sá Rodrigues, Chethana P. Gowda, Zhenqiu Liu, Archita Ghoshal
Publikováno v:
Oncogene
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is a multifunctional RNA-binding protein with an oncofetal pattern of expression shown to be implicated in the development of a variety of malignancies. In this study, we explored the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c65b9c623907b0fed4734784d8cf05b
https://doi.org/10.1038/s41388-019-0797-3
https://doi.org/10.1038/s41388-019-0797-3
Autor:
Shobhan Kuila, Sibasis Sahoo, Dileep Kumar Verma, Kirtishila Sonkar, A. Arockiasamy, Archita Ghoshal, Love Panchariya, Shubhashis Das, Rajkumar Halder, Abdul Hasan, Wajahat Ali Khan, Jitendra K. Thakur, Sujatha Sunil, Ankit Kumar
Zinc deficiency is linked to poor prognosis in COVID-19 patients while clinical trials with Zinc demonstrate better clinical outcome. The molecular target and mechanistic details of anti-coronaviral activity of Zinc remain obscure. We show that ionic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::286a25b1f8bd12654f6e8ee64ae779b3
https://doi.org/10.1101/2021.06.15.448551
https://doi.org/10.1101/2021.06.15.448551
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
The gap junction (GJ) protein connexin-43 (Cx43) is considered as a tumour suppressor protein for its role in reversing the phenotype of the cancer cells. In this study, we exploited the antitumor property of Cx43 in conjunction with the artesunate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7219830c46f70c70a15b548e932b7e
https://doaj.org/article/18312af788fa441992ba482539b4c824
https://doaj.org/article/18312af788fa441992ba482539b4c824
Publikováno v:
RSC Advances. 6:85763-85772
Targeting a specific pathway aberrantly upregulated in cancer cells has shown immense potential in cancer therapy. Although specific signaling pathways have been previously targeted for cancer therapy, the Wnt pathway has been rarely explored in this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64ca57f0e83e116a428a1e15abcd077e
https://doi.org/10.1039/c6ra16066b
https://doi.org/10.1039/c6ra16066b
Autor:
Upashi Goswami, Arun Chattopadhyay, Archita Ghoshal, Siddhartha Sankar Ghosh, Amaresh Kumar Sahoo
Publikováno v:
ACS Biomaterials Science & Engineering. 1:1256-1266
Secreted frizzled-related protein 1 (SFRP1) is a natural blocker of the Wnt signaling pathway in normal adult cells but is epigenetically silenced in cancer cells leading to aberrant proliferation. In this study, we have reported novel composite nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56939c66b72b920a041a9292317c0f61
https://doi.org/10.1021/acsbiomaterials.5b00305
https://doi.org/10.1021/acsbiomaterials.5b00305
Publikováno v:
Applied Biochemistry and Biotechnology. 175:2087-2103
Secreted frizzled-related proteins (sFRPs) constitute a family of proteins, which impede the Wnt signaling pathway. Upregulation of the Wnt cascade is one of the multiple facets of carcinogenesis. Herein, we report the expression, solubilization, pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4a35ef1b004b4ca5e93e07ccea4835
https://doi.org/10.1007/s12010-014-1354-8
https://doi.org/10.1007/s12010-014-1354-8
Publikováno v:
Molecular and cellular biochemistry. 418(1-2)
The Wnt signaling pathway plays a predominant role in aberrant proliferation in myriad of cancers. In non-cancerous cells, Wnts are blocked by the secreted frizzled-related proteins (sFRPs) that are generally downregulated in cancer cells. We have pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6bc4c7298f7b42e915360d59b45719
https://pubmed.ncbi.nlm.nih.gov/27334754
https://pubmed.ncbi.nlm.nih.gov/27334754