Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Archibald G. Prentice"'
Publikováno v:
British Journal of Haematology. 153:545-556
Chronic lymphocytic leukaemia (CLL) is the commonest haematological malignancy in the western world and is incurable by cytotoxic therapy. Considerable research effort has identified the signal transduction pathways in CLL cells that contribute to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47e9e989aaaf7211ce79095133c6df9
https://doi.org/10.1111/j.1365-2141.2011.08676.x
https://doi.org/10.1111/j.1365-2141.2011.08676.x
Autor:
Kenneth Koo, Donald Milligan, Sarah Jenkinson, Keith Wheatley, Carol Guy, David C. Linch, Yashma Patel, Alan Kenneth Burnett, Claire Green, Archibald G. Prentice, Anthony H. Goldstone, Amanda F. Gilkes, Robert Kerrin Hills, Rosemary E. Gale
Publikováno v:
Blood. 115:948-956
We investigated the benefit of adding all-trans retinoic acid (ATRA) to chemotherapy for younger patients with nonacute promyelocytic acute myeloid leukemia and high-risk myelodysplastic syndrome, and considered interactions between treatment and mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af8f168d4c816594d97cf6ecb73227f
https://doi.org/10.1182/blood-2009-08-236588
https://doi.org/10.1182/blood-2009-08-236588
Autor:
Cassandra Brookes, Donald Milligan, Andrew Howman, Keith Wheatley, Archibald G. Prentice, Anthony H. Goldstone, Alan Kenneth Burnett, Anthony V. Moorman
Publikováno v:
British Journal of Haematology. 145:598-605
This analysis, of 2483 patients with acute myeloid leukaemia (AML) aged 60+ years entered into two UK trials, was performed to determine the baseline parameters related to survival and to develop a risk index. The Medical Research Council (MRC) AML11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952e1fb3dc3742a7809931b72cc6ddf3
https://doi.org/10.1111/j.1365-2141.2009.07663.x
https://doi.org/10.1111/j.1365-2141.2009.07663.x
Autor:
Veronique Duke, Birunthini C. Yogashangary, Elisabeth P. Nacheva, Stephen M. Hart, Archibald G. Prentice, Julie Howard-Reeves, R. Gitendra Wickremasinghe, Kate Cwynarski, Andrew J. Steele, Panagiotis D. Kottaridis, A. Victor Hoffbrand, Lyubomir T. Vassilev
Publikováno v:
Blood. 112:3827-3834
The p53 protein plays a key role in securing the apoptotic response of chronic lymphocytic leukemia (CLL) cells to genotoxic agents. Transcriptional induction of proapoptotic proteins including Puma are thought to mediate p53-dependent apoptosis. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04971ad52d0294ababeab5838586eb21
https://doi.org/10.1182/blood-2008-05-156380
https://doi.org/10.1182/blood-2008-05-156380
Autor:
Veronique Duke, Archibald G. Prentice, Kanagasabai Ganeshaguru, Andrew J. Steele, Dylan T. Jones, Birunthini C. Yogashangary, Mark W. Lowdell, Janet North, Atul Mehta, RG Wickremasinghe, A. V. Hoffbrand, Panos Kottaridis
Publikováno v:
Leukemia. 20:1073-1079
We have studied the in vitro actions of the sesquiterpene lactone parthenolide (PTL) on cells isolated from patients with chronic lymphocytic leukemia (CLL). Dye reduction viability assays showed that the median LD(50) for PTL was 6.2 muM (n=78). Fif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4287e1f7be730c445d8b9afdbe82f8
https://doi.org/10.1038/sj.leu.2404230
https://doi.org/10.1038/sj.leu.2404230
Autor:
Steffen Engelhart, C. Hahn, Ingo G.H. Schmidt-Wolf, Benjamin Djulbegovic, Archibald G. Prentice, Axel Glasmacher, Marcus Gorschlüter
Publikováno v:
Journal of Clinical Oncology. 21:4615-4626
Purpose: Efficacy of antifungal prophylaxis has not yet been convincingly proven in numerous trials of various antifungals. New evidence and the anti-Aspergillus efficacy of itraconazole prompted a new look at the data for the prevention of invasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e825306a8165ea4e7a11264b121bb3
https://doi.org/10.1200/jco.2003.04.052
https://doi.org/10.1200/jco.2003.04.052
Autor:
Christopher McNamara, Derralynn Hughes, Simon Richardson, Kate Cwynarski, Archibald G. Prentice, Anmol Malhotra
Publikováno v:
British Journal of Haematology. 149:899-901
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8240a53a73c7c341e964300f0d1edd8f
https://doi.org/10.1111/j.1365-2141.2010.08112.x
https://doi.org/10.1111/j.1365-2141.2010.08112.x
Publikováno v:
Ultrasound in Medicine & Biology. 26:977-980
Not all women with the polycystic ovary syndrome (PCOS) on ultrasound (US) will have the syndrome, and clinical and biochemical features of PCOS may be present without US features. The sensitivity of US in detecting PCOS was, therefore, prospectively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dcd33297f6f23ef0d4796100686faf
https://doi.org/10.1016/s0301-5629(00)00219-2
https://doi.org/10.1016/s0301-5629(00)00219-2
Autor:
Steve Shaw, Terence J. Wilkin, Robert Fox, J. E. Condon, J Friend, Archibald G. Prentice, William Atiomo
Publikováno v:
Clinical Endocrinology. 52:487-492
Summary BACKGROUND It has been postulated that an insulln-driven increase in plasminogen activator inhibitor-1 (PAI-1) levels may link insulin resistance to anovulatory infertility in women with PCOS and that It may place them at increased risk of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86456e615c97ba86c78211f20e3a5a09
https://doi.org/10.1046/j.1365-2265.2000.00946.x
https://doi.org/10.1046/j.1365-2265.2000.00946.x
Autor:
H. Grant Prentice, G. R. Morgenstern, Archibald G. Prentice, Stephen Schey, David W. Warnock, Janet E. Ropner
Publikováno v:
British Journal of Haematology. 105:901-911
Fluconazole is widely used as antifungal prophylaxis but it is ineffective against Aspergillus. Itraconazole has a broader spectrum of activity but the capsules give erratic bioavailability in neutropenic patients. We compared itraconazole oral solut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2b51714190eb2d583bd05b729b1d3dc
https://doi.org/10.1046/j.1365-2141.1999.01465.x
https://doi.org/10.1046/j.1365-2141.1999.01465.x