Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Archibald Agyekum-Yamoah"'
Autor:
David O. Osei-Hwedieh, Abigail L. Sedlacek, Luis Mena Hernandez, Archibald Agyekum Yamoah, Swati G. Iyer, Kurt R. Weiss, Robert J. Binder
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
T cells recognize tumor-derived mutated peptides presented on MHC by tumors. The recognition of these neo-epitopes leads to rejection of tumors, an event that is critical for successful cancer immunosurveillance. Determination of tumor-rejecting neo-
Externí odkaz:
https://doaj.org/article/d8f0223374d04824b7fc12598b9767b9
Autor:
Abigail L Sedlacek, David Osei-Hwedieh, Archibald Agyekum-Yamoah, Luis Mena, Swati Iyer, Kurt Weiss, Robert J Binder
Publikováno v:
The Journal of Immunology. 208:179.12-179.12
T cells recognize tumor neoantigens (TNag) in the context of MHC and eliminate cells which express these antigens, leaving those lacking immunodominant epitopes. Central to investigating tumor immunoediting is the ability to define immunogenic TNag.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95ce8529fce6cdc4464b3a2edf02e3a8
https://doi.org/10.4049/jimmunol.208.supp.179.12
https://doi.org/10.4049/jimmunol.208.supp.179.12
Autor:
Joseph M. Ryan, Julia Svedova, Rebecca Abblett, Adam T. Hagymasi, Matthew P. Hanley, Anthony T. Vella, Steven L. Reiner, Marie-Clare St. Rose, Adam J. Adler, Payal Mittal, Archibald Agyekum-Yamoah
Publikováno v:
The Journal of Immunology. 200:1513-1526
Agonists to the TNF/TNFR costimulatory receptors CD134 (OX40) and CD137 (4-1BB) elicit antitumor immunity. Dual costimulation with anti-CD134 plus anti-CD137 is particularly potent because it programs cytotoxic potential in CD8+ and CD4+ T cells. Cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22b70b0a05fb1efe9cc0c68f5349239
https://doi.org/10.4049/jimmunol.1701039
https://doi.org/10.4049/jimmunol.1701039