Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Archana Varadaraj"'
Publikováno v:
Bio-Protocol, Vol 8, Iss 16 (2018)
Fibronectin (FN) is an extracellular matrix protein that is secreted by many cell types and binds predominantly to the cell surface receptor Integrin α5β1. Integrin α5β1 binding initiates the step-wise assembly of FN into fibrils, a process calle
Externí odkaz:
https://doaj.org/article/47a01eb9d05548d893c801a1204fee4c
Autor:
Archana Varadaraj, Pratik Patel, Anne Serrao, Tirthankar Bandyopadhay, Nam Y. Lee, Amir A. Jazaeri, Zhiqing Huang, Susan K. Murphy, Karthikeyan Mythreye
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 11, Pp 826-838 (2015)
Anoikis, a cell death mechanism triggered upon cell-matrix detachment, is regarded as a physiological suppressor of metastasis that can be regulated by a diverse array of signals. The protein encoded by GDF2 is BMP9 and is a member of the bone morpho
Externí odkaz:
https://doaj.org/article/ca70dc14342c4009be0783c537ea963d
Autor:
Tina Rich, Archana Varadaraj
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1014 (2007)
Intranuclear inclusion bodies (IBs) are the histopathologic markers of multiple protein folding diseases. IB formation has been extensively studied using fluorescent fusion products of pathogenic polyglutamine (polyQ) expressing proteins. These studi
Externí odkaz:
https://doaj.org/article/0b685e96490f47fe8fdc3b9750bf5733
Autor:
Jogendra S. Pawar, Archana Varadaraj, Carina Magdaleno, Sophia Carvalho, Narendiran Rajasekaran, Trenton House
Publikováno v:
Journal of Cellular Biochemistry
Fibronectin (FN) is an extracellular matrix (ECM) glycoprotein that self‐assembles into FN fibrils, forming a FN matrix contributing to the stiffness of the ECM. Stromal FN stiffness in cancer has been shown to impact epithelial functions such as m
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Fibronectin (FN) is a core matrix protein that assembles to form a dynamic cellular scaffold, frequently perturbed during oncogenic transformation. Tumor hypoxia, characterized by low oxygen concentrations in the microenvironment of most solid tumors
Autor:
Emily Cluff, Carina C. Magdaleno, Emyly Fernandez, Trenton House, Srividya Swaminathan, Archana Varadaraj, Narendiran Rajasekaran
Publikováno v:
Cancer immunology, immunotherapy : CII. 71(8)
Natural killer (NK) cells are cytotoxic innate lymphocytes that are specialized to kill tumor cells. NK cells are responsive to the primary cytokine IL-2 in the tumor microenvironment (TME), to activate its effector functions against tumors. Despite
Publikováno v:
The Journal of Immunology. 208:62.08-62.08
Natural Killer cells (NK), the major innate effector cells, with their broad cytotoxicity against tumors are ideal candidates for immunotherapy. Once having entered the malignant site, NK cells encounter a complex environment composed of tumor cells,
Publikováno v:
Scientific Reports
Fibronectin (FN) is a core matrix protein that assembles to form a dynamic cellular scaffold, frequently perturbed during oncogenic transformation. Tumor hypoxia, characterized by low oxygen concentrations in the microenvironment of most solid tumors
Autor:
Zhiqing Huang, Nam Y. Lee, Susan K. Murphy, Archana Varadaraj, Amir A. Jazaeri, Pratik Patel, Karthikeyan Mythreye, Anne Serrao, Tirthankar Bandyopadhay
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 11, Pp 826-838 (2015)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Anoikis, a cell death mechanism triggered upon cell-matrix detachment, is regarded as a physiological suppressor of metastasis that can be regulated by a diverse array of signals. The protein encoded by GDF2 is BMP9 and is a member of the bone morpho
Publikováno v:
IUBMB Life. 66:27-33
Viruses alter specific host cell targets to counteract possible defense mechanisms aimed at eliminating infectivity and viral propagation. The SUMO conjugating enzyme Ubc9 functions as a hub for protein sumoylation, whilst also providing an interacti