Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Archana V Boopathy"'
Autor:
Archana V. Boopathy, Bhawna Sharma, Anurag Nekkalapudi, Raphaela Wimmer, Maria Gamez-Guerrero, Silpa Suthram, Hoa Truong, Johnny Lee, Jiani Li, Ross Martin, Wade Blair, Romas Geleziunas, Klaus Orlinger, Sarah Ahmadi-Erber, Henning Lauterbach, Tariro Makadzange, Brie Falkard, Sarah Schmidt
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract HIV affects more than 38 million people worldwide. Although HIV can be effectively treated by lifelong combination antiretroviral therapy, only a handful of patients have been cured. Therapeutic vaccines that induce robust de novo immune res
Externí odkaz:
https://doaj.org/article/eb705fb1db0442ae88ed8c11cf33d6bc
Autor:
Apoorva S Salimath, Edward A Phelps, Archana V Boopathy, Pao-lin Che, Milton Brown, Andrés J García, Michael E Davis
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50980 (2012)
Acute myocardial infarction (MI) caused by ischemia and reperfusion (IR) is the most common cause of cardiac dysfunction due to local cell death and a temporally regulated inflammatory response. Current therapeutics are limited by delivery vehicles t
Externí odkaz:
https://doaj.org/article/c69a3f7d42f74d619d891553e2adab94
Autor:
Brian M. Cieslewicz, Jordan A. Stinson, E. Bart Tarbet, Yichen Zhang, Matthew Dirckx, Kathryn M. Kosuda, Archana V. Boopathy, Nickolas W. Hartman, David P. Miller, Jonathan A. Kluge, Brett L. Hurst
Publikováno v:
Vaccine
Traditional bolus vaccine administration leads to rapid clearance of vaccine from lymphoid tissue. However, there is increasing evidence suggesting that the kinetics of antigen delivery can impact immune responses to vaccines, particularly when tailo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83f9866a8759604f762ad323d956e0a
https://europepmc.org/articles/PMC8405573/
https://europepmc.org/articles/PMC8405573/
Autor:
Kirti Kaushik, Amit A. Upadhyay, Ben Murrell, Etse H. Gebru, Pallavi Dhadvai, William R. Schief, Bryan Briney, Darrell J. Irvine, Colin Havenar-Daughton, Federico Viviano, Guido Silvestri, Yury Chloe, Steven E. Bosinger, Samantha M. Reiss, Dennis R. Burton, Archana V. Boopathy, Diane G. Carnathan, Chiamaka A. Enemuo, Shane Crotty
Publikováno v:
SSRN Electronic Journal.
The first immunization in a protein prime-boost vaccination is likely to be a critical event for how the immune response unfolds. However, priming immunizations generally produce little circulating antibody (Ab) or T cell responses in blood and there
Autor:
Christopher J. Love, Michelle E. Turvey, Paula T. Hammond, Mary E. Welch, Anasuya Mandal, Nikki Thai, Lionel K.W. Lam, Kelly D. Moynihan, Jenny H. Van, Darrell J. Irvine, Archana V. Boopathy, Nitasha R. Bennett
Publikováno v:
Prof. Hammond via Ye Li
Important cell populations reside within tissues and are not accessed by traditional blood draws used to monitor the immune system. To address this issue at an essential barrier tissue, the skin, we created a microneedle-based technology for longitud
Autor:
Ming Shen, Michael Davis, Udit Agarwal, Janet D. Fernandez, Brian Kogon, Kristin M. French, Milton E. Brown, David Trac, Alex George, Archana V. Boopathy, Amanda Walker Smith, Baahaldin Alsoufi, Kirk R. Kanter, Manu O. Platt, Rong Jiang, Mary B. Wagner
Publikováno v:
Stem Cells Translational Medicine
To investigate the role of age of human pediatric cardiac progenitor cells (hCPCs) on ventricular remodeling, the authors injected neonate, infant, or child hCPCs into rats with right ventricular heart failure. Mechanisms including migration and prol
Autor:
Milton E. Brown, Kiwon Ban, Andrés J. García, Yoshie Narui, Inthirai Somasuntharam, E. Bernadette Cabigas, Young Sup Yoon, Thomas H. Barker, Archana V. Boopathy, Vincent F. Fiore, Pao Lin Che, Michael Davis, Khalid Salaita
Publikováno v:
Biomaterials. 35:8103-8112
Myocardial infarction is the leading cause of death worldwide and phase I clinical trials utilizing cardiac progenitor cells (CPCs) have shown promising outcomes. Notch1 signaling plays a critical role in cardiac development and in the survival, card
Autor:
Archana V. Boopathy, E. Bernadette Cabigas, Srishti Bhutani, Pao Lin Che, Gitangali Baroi, Michael Davis, Ming Shen, Jie Liu, Brian H. Crawford, Mary B. Wagner
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 20:93-103
In the adult heart, catalase (CAT) activity increases appropriately with increasing levels of hydrogen peroxide, conferring cardioprotection. This mechanism is absent in the newborn for unknown reasons. In the present study, we examined how the postt
Autor:
Milton E. Brown, Raffay S. Khan, Inthirai Somasuntharam, Niren Murthy, Archana V. Boopathy, Mario D. Martinez, Michael Davis
Publikováno v:
Biomaterials. 34:7790-7798
Myocardial infarction (MI) is the most common cause of heart failure (HF), the leading cause of death in the developed world. Oxidative stress due to excessive production of reactive oxygen species (ROS) plays a key role in the pathogenesis of cardia
Autor:
Michael Davis, Gokulakrishnan Seshadri, Milton E. Brown, Pao Lin Che, Karl D. Pendergrass, Kathryn Maiellaro-Rafferty, Archana V. Boopathy
Publikováno v:
Stem Cells and Development. 22:2414-2424
There are a limited number of therapies available to prevent heart failure following myocardial infarction. One novel therapy that is currently being pursued is the implantation of cardiac progenitor cells (CPCs); however, their responses to oxidativ