Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Archana Unnikrishnan"'
Autor:
Kavitha Kurup, Shivani N Mann, Jordan Jackson, Stephanie Matyi, Michelle Ranjo-Bishop, Willard M Freeman, Michael B Stout, Arlan Richardson, Archana Unnikrishnan
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0237199 (2021)
Nutritional manipulations early in life have been shown to influence growth rate and elicit long lasting effects which in turn has been found to impact lifespan. Therefore, we studied the long-term effects of pre-weaning dietary restriction implement
Externí odkaz:
https://doaj.org/article/280e20be37f448c89f16b203045c092e
Autor:
Shivani N Mann, Niran Hadad, Molly Nelson Holte, Alicia R Rothman, Roshini Sathiaseelan, Samim Ali Mondal, Martin-Paul Agbaga, Archana Unnikrishnan, Malayannan Subramaniam, John Hawse, Derek M Huffman, Willard M Freeman, Michael B Stout
Publikováno v:
eLife, Vol 9 (2020)
Metabolic dysfunction underlies several chronic diseases, many of which are exacerbated by obesity. Dietary interventions can reverse metabolic declines and slow aging, although compliance issues remain paramount. 17α-estradiol treatment improves me
Externí odkaz:
https://doaj.org/article/1b1546f66bc7437c80062d0bfab7f142
Autor:
Ali M. Fardous, Safa Beydoun, Andrew A. James, Hongzhi Ma, Diane C. Cabelof, Archana Unnikrishnan, Ahmad R. Heydari
Publikováno v:
Nutrients, Vol 14, Iss 1, p 16 (2021)
Diet plays a crucial role in the development of colorectal cancer (CRC). Of particular importance, folate, present in foods and supplements, is a crucial modulator of CRC risk. The role of folate, and, specifically, the synthetic variant, folic acid,
Externí odkaz:
https://doaj.org/article/a3152446136f45b6aadb0da670a53ff7
Autor:
Yiqiang Zhang, Archana Unnikrishnan, Sathyaseelan S. Deepa, Yuhong Liu, Yan Li, Yuji Ikeno, Danuta Sosnowska, Holly Van Remmen, Arlan Richardson
Publikováno v:
Redox Biology, Vol 11, Iss , Pp 30-37 (2017)
In contrast to other mouse models that are deficient in antioxidant enzymes, mice null for Cu/Zn-superoxide dismutase (Sod1−/− mice) show a major decrease in lifespan and several accelerated aging phenotypes. The goal of this study was to determi
Externí odkaz:
https://doaj.org/article/390d6b68054645dfa11aeef78231ca4f
Autor:
Stephanie Matyi, Xiwei Chen, Michelle Ranjo-Bishop, Keisuke Ejima, Stephanie L. Dickinson, David B. Allison, Karla Garrett, Archana Unnikrishnan, Arlan Richardson
Publikováno v:
Aging Cell
Dietary restriction (DR) was reported to either have no effect or reduce the lifespan of the majority of the 41‐recombinant inbred (RI) lines studied by Liao et al. (Aging Cell, 2010, 9, 92). In an appropriately power longevity study (n > 30 mice/g
Autor:
Stephanie L. Dickinson, Xiwei Chen, Karla Garrett Garrett, David B. Allison, Arlan Richardson, Archana Unnikrishnan, Michelle Ranjo-Bishop, Keisuke Ejima, Stephanie Matyi
Dietary restriction (DR) was reported to either have no effect or reduced the lifespan of the majority of the 41-recombinant inbred (RI)-lines studied (Liao et al., 2010). In an appropriately power longevity study (n > 30 mice/group), we measured the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a080a18cf3cc232dd298ed878c168704
https://doi.org/10.1101/2021.06.25.449984
https://doi.org/10.1101/2021.06.25.449984
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Since the initial suggestion that rapamycin, an inhibitor of target of rapamycin (TOR) nutrient signaling, increased lifespan comparable to dietary restriction, investigators have viewed rapamycin as a potential dietary restriction mimetic. Both diet
Autor:
Archana Unnikrishnan
Publikováno v:
Innovation in Aging
Stem cells play a critical role in the maintenance of tissue function and their proliferative/regenerative capacity is essential to this role. Because stem cells persist over the lifespan of an animal, they are susceptible to gradual accumulation of
Autor:
Jordan Jackson, Michelle Ranjo-Bishop, Archana Unnikrishnan, Michael B Stout, Shivani N. Mann, Stephanie Matyi, Arlan Richardson, Kavitha Kurup, Willard M. Freeman
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0237199 (2021)
PLoS ONE
PLoS ONE
Nutritional manipulations early in life have been shown to influence growth rate and elicit long lasting effects which in turn has been found to impact lifespan. Therefore, we studied the long-term effects of pre-weaning dietary restriction implement
Autor:
Willard M. Freeman, Niran Hadad, Alicia R. Rothman, Derek M. Huffman, Samim Ali Mondal, Molly Nelson Holte, Shivani N. Mann, Archana Unnikrishnan, Michael B. Stout, Roshini Sathiaseelan, John R. Hawse, Martin-Paul Agbaga, Malayannan Subramaniam
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Metabolic dysfunction underlies several chronic diseases, many of which are exacerbated by obesity. Dietary interventions can reverse metabolic declines and slow aging, although compliance issues remain paramount. 17α-estradiol treatment improves me