Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Archana Shankar"'
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Akademický článek
Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression
Autor: Trine Line Hauge Okholm, Shashank Sathe, Samuel S. Park, Andreas Bjerregaard Kamstrup, Asta Mannstaedt Rasmussen, Archana Shankar, Zong Ming Chua, Niels Fristrup, Morten Muhlig Nielsen, Søren Vang, Lars Dyrskjøt, Stefan Aigner, Christian Kroun Damgaard, Gene W. Yeo, Jakob Skou Pedersen
Publikováno v: Genome Medicine, Vol 12, Iss 1, Pp 1-22 (2020)
Abstract Background Circular RNAs (circRNAs) are stable, often highly expressed RNA transcripts with potential to modulate other regulatory RNAs. A few circRNAs have been shown to bind RNA-binding proteins (RBPs); however, little is known about the p
Externí odkaz: https://doaj.org/article/07a2b5a8c7034ce9ae1a8efb8d815836
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4
MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy
Autor: Kathryn H. Morelli, Wenhao Jin, Shashank Shathe, Assael A. Madrigal, Krysten L. Jones, Joshua L. Schwartz, Tristan Bridges, Jasmine R. Mueller, Archana Shankar, Isaac A. Chaim, John W. Day, Gene W. Yeo
Publikováno v: Sci Transl Med
Myotonic dystrophy type 1 (DM1) is a multisystem, autosomal-dominant inherited disorder caused by CTG microsatellite repeat expansions (MREs) in the 3′ untranslated region of the dystrophia myotonica-protein kinase ( DMPK ) gene. Despite its promin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6fa1febd240558019bfb8e656619b8
https://europepmc.org/articles/PMC9645119/
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5
Complete Tolerogenic Adjuvant Stimulates Regulatory T Cell Response to Immunization
Autor: Guoxing Zheng, Yajun Geng, Zhaoqi Yan, Soo Min Shin, Kanak Joshi, Anjali Panicker, Archana Shankar, Ramya Elangovan, Jason Koehler, Varun Gnanasekar, Jessica Ann Gilles, Gnanasekar Munirathinam, Aoshuang Chen
Publikováno v: Journal of immunology (Baltimore, Md. : 1950).
We have determined in mice the minimum composition required for forming a vaccine adjuvant that stimulates a regulatory T (Treg) cell response to immunization, and we named the adjuvant “complete tolerogenic adjuvant.” This new kind of adjuvant m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06448ecb7b45f0193c03d3933773d3bf
https://pubmed.ncbi.nlm.nih.gov/36602931
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6
A role for alternative splicing in circadian control of exocytosis and glucose homeostasis
Autor: Akihiko Taguchi, Biliana Marcheva, Gene W. Yeo, Emily C. Wheeler, Patrick E. MacDonald, Chiaki Omura, Marsha V. Newman, Yumiko Kobayashi, Eugene Wyatt, Mark Perelis, Archana Shankar, Jocelyn E. Manning Fox, Elizabeth M. McNally, Hee Kyung Hong, Benjamin J. Weidemann, Haopeng Lin, Kathryn Moynihan Ramsey, Joseph Bass
Publikováno v: Genes Dev
The circadian clock is encoded by a negative transcriptional feedback loop that coordinates physiology and behavior through molecular programs that remain incompletely understood. Here, we reveal rhythmic genome-wide alternative splicing (AS) of pre-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4eb5d12e23aa7ee90970e13a53dc3e
https://doi.org/10.1101/gad.338178.120
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9
Identification and Characterization of a Minimal Functional Splicing Regulatory Protein, PTBP1
Autor: Enoch Kim, Niroshika Keppetipola, Adrian Lino Hernandez Lopez, Archana Shankar, Robert Jordan Ontiveros, Luis Hernandez, Haylena Nguyen
Publikováno v: Biochemistry
Polypyrimidine tract binding protein 1 (PTBP1) is a well-studied RNA binding protein that serves as an important model for understanding molecular mechanisms underlying alternative splicing regulation. PTBP1 has four RNA binding domains (RBDs) connec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7477e46dcf62a3455e3b7e7f2e16abbc
https://europepmc.org/articles/PMC7821650/
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10
Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression
Autor: Zong Ming Chua, Andreas Bjerregaard Kamstrup, Lars Dyrskjøt, Trine Line Hauge Okholm, Samuel S. Park, Søren Vang, Asta Mannstaedt Rasmussen, Archana Shankar, Niels Fristrup, Gene W. Yeo, Christian Kroun Damgaard, Jakob Skou Pedersen, Stefan Aigner, Morten Nielsen, Shashank Sathe
Publikováno v: Okholm, T L H, Sathe, S, Park, S S, Kamstrup, A B, Rasmussen, A M, Shankar, A, Chua, Z M, Fristrup, N, Nielsen, M M, Vang, S, Dyrskjøt, L, Aigner, S, Damgaard, C K, Yeo, G W & Pedersen, J S 2020, ' Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression ', Genome Medicine, vol. 12, no. 112, 112 . https://doi.org/10.1186/s13073-020-00812-8
Genome medicine, vol 12, iss 1
Genome Medicine
Genome Medicine, Vol 12, Iss 1, Pp 1-22 (2020)
Background Circular RNAs (circRNAs) are stable, often highly expressed RNA transcripts with potential to modulate other regulatory RNAs. A few circRNAs have been shown to bind RNA-binding proteins (RBPs); however, little is known about the prevalence
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a54ae74f87ccea3fb3366dcb515b51
https://pure.au.dk/ws/files/202316983/Okholm_et_al_2020_Genome_Medicine.pdf
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