Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Archana Krovi"'
Autor:
Talisa S. Kinsale, Mackenzie L. Cottrell, Linying Li, Rhonda Brand, Greg Gatto, Ellen Luecke, Chasity Norton, Archana Krovi, Julie B. Dumond, Gauri Rao, Shekhar Yeshwante, Brian Van Horne, Ariane Van Der Straten, Angela D. M. Kashuba, Leah M. Johnson
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 201 (2024)
Long-acting injectable cabotegravir is more effective than daily oral PrEP at preventing HIV transmission due to improved adherence, but requires bi-monthly large-volume intramuscular injections. Subcutaneous (SC) contraceptive implants can be formul
Externí odkaz:
https://doaj.org/article/5e3b180f2a7545f595dc9df71e45e098
Autor:
Michele B. Daly, Andres Wong-Sam, Linying Li, Archana Krovi, Gregory J. Gatto, Chasity Norton, Ellen H. Luecke, Victoria Mrotz, Catalina Forero, Mackenzie L. Cottrell, Amanda P. Schauer, Joy Gary, Josilene Nascimento-Seixas, James Mitchell, Ariane van der Straten, Walid Heneine, J. Gerardo Garcίa-Lerma, Charles W. Dobard, Leah M. Johnson
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2676 (2023)
The prevention of HIV and unintended pregnancies is a public health priority. Multi-purpose prevention technologies capable of long-acting HIV and pregnancy prevention are desirable for women. Here, we utilized a preclinical macaque model to evaluate
Externí odkaz:
https://doaj.org/article/3ac783c0b3c04b168eab70e7aa6df9d0
Autor:
Linying Li, Chanhwa Lee, Daniela F. Cruz, Sai Archana Krovi, Michael G. Hudgens, Mackenzie L. Cottrell, Leah M. Johnson
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1226 (2022)
Controlled drug delivery systems can provide sustained release profiles, favorable pharmacokinetics, and improved patient adherence. Here, a reservoir-style implant comprising a biodegradable polymer, poly(ε-caprolactone) (PCL), was developed to del
Externí odkaz:
https://doaj.org/article/0186f279a37a4c7a8f7d3e78a736a321
Autor:
Sai Archana Krovi, Maria M. Moreno Caffaro, Shyam Aravamudhan, Ninell P. Mortensen, Leah M. Johnson
Publikováno v:
Nanomaterials, Vol 12, Iss 15, p 2699 (2022)
Microplastics (MPs) and nanoplastics (NPs) exist in certain environments, beverages, and food products. However, the ultimate risk and consequences of MPs and NPs on human health remain largely unknown. Studies involving the biological effects of sma
Externí odkaz:
https://doaj.org/article/90952f12d15048eb8e698faab21ac5ef
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1057 (2020)
A critical need exists to develop diverse biomedical strategies for the widespread use of HIV Pre-Exposure Prophylaxis (HIV PrEP). This manuscript describes a subcutaneous reservoir-style implant for long-acting delivery of tenofovir alafenamide (TAF
Externí odkaz:
https://doaj.org/article/73cb1c8ef2e4442085f655fd6d3a2f58
Autor:
Zayda L Piedra-Quintero, Mireia Guerau-de-Arellano, Abriana Kroboth, Meital Eckshtain-Levi, Rebeca T Stiepel, Sai Archana Krovi, Kristy M. Ainslie, Christopher J Genito, Eric M. Bachelder
Publikováno v:
Bioconjugate Chemistry. 32:1629-1640
Macrophage-mediated inflammation drives autoimmune and chronic inflammatory diseases. Treatment with anti-inflammatory agents can be an effective strategy to reduce this inflammation; however, high concentrations of these agents can have immune-dampe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ea41cbd476927593295c78c1ea6c92
https://doi.org/10.1021/acs.bioconjchem.1c00200
https://doi.org/10.1021/acs.bioconjchem.1c00200
Autor:
Leah M. Johnson, Sai Archana Krovi, Linying Li, Natalie Girouard, Zach R. Demkovich, Daniel Myers, Ben Creelman, Ariane van der Straten
Publikováno v:
Pharmaceutics, Vol 11, Iss 7, p 315 (2019)
Long-acting (LA) HIV pre-exposure prophylaxis (PrEP) offers the potential to improve adherence by lowering the burden of daily or on-demand regimens of antiretroviral (ARV) drugs. This paper details the fabrication and in vitro performance of a subcu
Externí odkaz:
https://doaj.org/article/883073d8b1b24b6a82e05b259999c461
Autor:
Ariane van der Straten, Gregory Gatto, Mackenzie L. Cottrell, Sai Archana Krovi, Leah M. Johnson, Rhonda M. Brand, Linying Li, Chasity Antoninette Norton
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 340
Women worldwide confront two major reproductive health challenges: the need for contraception and protection from sexually transmitted infections, including Human Immunodeficiency Virus (HIV). Multipurpose Prevention Technologies (MPTs) that simultan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf28ab42f0d42f2f8d1c96283745cb4
https://pubmed.ncbi.nlm.nih.gov/34678316
https://pubmed.ncbi.nlm.nih.gov/34678316
Publikováno v:
Pharmaceutics, Vol 12, Iss 1057, p 1057 (2020)
Pharmaceutics
Volume 12
Issue 11
Pharmaceutics
Volume 12
Issue 11
A critical need exists to develop diverse biomedical strategies for the widespread use of HIV Pre-Exposure Prophylaxis (HIV PrEP). This manuscript describes a subcutaneous reservoir-style implant for long-acting delivery of tenofovir alafenamide (TAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88aaccfc7f2c011a5928f5c1e844e115
https://www.mdpi.com/1999-4923/12/11/1057
https://www.mdpi.com/1999-4923/12/11/1057
Autor:
Alexander L. Kovach, Timothy R. Fennell, Ninell P. Mortensen, Jeffrey Brent Mecham, Shyam Aravamudhan, Leah M. Johnson, Maria Moreno Caffaro, Sai Archana Krovi
Publikováno v:
Nanoscale advances. 3(2)
Fluorescent nanoparticles (NPs) comprising polyethylene terephthalate (PET) with a hydrodynamic diameter of 158 ± 2 nm were synthesized in a bottom-up approach. Concentration-dependent uptake and cytotoxicity of PET NPs in macrophages are shown. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51b6c4cf243723c78e48cebafe0cfcb
https://pubmed.ncbi.nlm.nih.gov/36131728
https://pubmed.ncbi.nlm.nih.gov/36131728