Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Archana Kapoor"'
Autor:
Mithlesh Yadav, Suraj N. Mali, Bharti Sharma, Haya Yasin, Rohit Pal, Gurubasavaraja Swamy Purawarga Matada, Archana Kapoor
Publikováno v:
Chemical Physics Impact, Vol 9, Iss , Pp 100705- (2024)
This study reports the synthesis and characterization of a novel series of 5-nitro-N-phenyl-3-(phenylamino)-1H-indazole-1-carboxamide derivatives (5a-5v) obtained through the reaction of 3-chloro-5-nitro-N-phenyl-1H-indazole-1-carboxamide (4) with di
Externí odkaz:
https://doaj.org/article/11de1dff598042a98ed188f2bdaac63d
Publikováno v:
Current Chemistry Letters, Vol 13, Iss 1, Pp 225-240 (2024)
The study aimed to explore the anticancer efficacy of indazole pharmacophore by analyzing a series of 109 derivatives of indazole as Tyrosine Threonine Kinase (TTK) inhibitors through quantitative activity relationship analysis using 2D and 3D QSAR t
Externí odkaz:
https://doaj.org/article/e7a7111bcc564655b7fd60bc3b8e8b62
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 9, Iss 1, Pp 1-15 (2023)
Highlights Comparative evaluation of melt and solvent evaporation techniques for synthesis of dithranol nanosponges. The particle characteristics were investigated using FTIR, DSC, PXRD and surface morphology. Tuning of size and crystallinity of nano
Externí odkaz:
https://doaj.org/article/241ef0fc8e1d436ab789a42c8b0ce903
Formulation, Characterization, Anti-Inflammatory and Cytotoxicity Study of Sesamol-Laden Nanosponges
Autor:
Anroop B. Nair, Pooja Dalal, Varsha Kadian, Sunil Kumar, Archana Kapoor, Minakshi Garg, Rekha Rao, Bandar Aldhubiab, Nagaraja Sreeharsha, Rashed M. Almuqbil, Mahesh Attimarad, Heba S. Elsewedy, Pottathil Shinu
Publikováno v:
Nanomaterials, Vol 12, Iss 23, p 4211 (2022)
Sesamol (SES) possesses remarkable chemotherapeutic activity, owing to its anti-inflammatory and antioxidant potential. However, the activity of SES is mainly hampered by its poor physicochemical properties and stability issues. Hence, to improve the
Externí odkaz:
https://doaj.org/article/b587ef382e784bdcb05f78457ee1e2b0
Autor:
Wataru Nishimura, Archana Kapoor, Ilham El Khattabi, Wanzhu Jin, Kazuki Yasuda, Susan Bonner-Weir, Arun Sharma
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142286 (2015)
Early in pancreatic development, epithelial cells of pancreatic buds function as primary multipotent progenitor cells (1°MPC) that specify all three pancreatic cell lineages, i.e., endocrine, acinar and duct. Bipotent "Trunk" progenitors derived fro
Externí odkaz:
https://doaj.org/article/e10f0eefb4ee46629e5b2ae7dc92dfd0
Autor:
Didier Vingadassalom, Kenneth G Campellone, Michael J Brady, Brian Skehan, Scott E Battle, Douglas Robbins, Archana Kapoor, Gail Hecht, Scott B Snapper, John M Leong
Publikováno v:
PLoS Pathogens, Vol 6, Iss 8, p e1001056 (2010)
Upon infection of mammalian cells, enterohemorrhagic E. coli (EHEC) O157:H7 utilizes a type III secretion system to translocate the effectors Tir and EspF(U) (aka TccP) that trigger the formation of F-actin-rich 'pedestals' beneath bound bacteria. Es
Externí odkaz:
https://doaj.org/article/ef15d42bff434646ac26668f7b7550c6
Autor:
Grace L Chen, Runa Mithani, Archana Kapoor, Sophia Lu, Laila El Asmar, Catherine A Panozzo, Christine A Shaw, Sonia K Stoszek, Allison August
Publikováno v:
Open Forum Infectious Diseases. 9
Background Respiratory syncytial virus (RSV) is a public health burden; no vaccine is currently available. An mRNA-based RSV vaccine (mRNA-1345) encoding the RSV prefusion stabilized F (preF) glycoprotein is under clinical investigation. Methods A ph
Publikováno v:
International Journal of Life Science and Pharma Research.
Recently, QSAR technique and molecular docking have become widespread in designing new series of compounds, depending upon the different models developed, before actually synthesizing and testing them. Due to the diverse activity profile of substitut
Publikováno v:
AAPS PharmSciTech. 23(4)
The present piece of research work is framed for improving the solubility of ketoprofen by forming co-crystal using fumaric acid as a coformer. Co-crystal of ketoprofen and fumaric acid was prepared by simple solvent-assisted grinding method, contain
Publikováno v:
European Journal of Medicinal Chemistry. 242:114655
Monoamine oxidase enzyme is necessary for the management of brain functions. It oxidatively metabolizes monoamines and produces ammonia, aldehyde and hydrogen peroxide as by-products. Excessive production of by-products of monoamine metabolism genera