Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Archana, Sanjay"'
Autor:
Sanja Novak, Josip Madunic, Laura Shum, Milan Vucetic, Xi Wang, Hitoshi Tanigawa, Mallika Ghosh, Archana Sanjay, Ivo Kalajzic
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Bone regeneration depends on a pool of bone/cartilage stem/progenitor cells and signaling mechanisms regulating their differentiation. Using in vitro approach, we have shown that PDGF signaling through PDGFRβ inhibits BMP2-induced osteogene
Externí odkaz:
https://doaj.org/article/a7c137547cfb430cba4dd638240ac905
Autor:
Laura Doherty, Archana Sanjay
Publikováno v:
JBMR Plus, Vol 4, Iss 7, Pp n/a-n/a (2020)
ABSTRACT Leucine‐rich repeat‐containing G protein‐coupled receptors (LGRs) are adult stem cell markers that have been described across various stem cell niches, and expression of LGRs and their corresponding ligands (R‐spondins) has now been
Externí odkaz:
https://doaj.org/article/5df1e939a9ae46229db182f0407af1bd
Publikováno v:
Bone Reports, Vol 10, Iss , Pp - (2019)
Our previous studies showed that in a mouse model in which PI3K-AKT activation was increased (YF mice), osteoclast numbers and levels of SDF-1, a chemokine, were augmented. The purpose of this study was to delineate the role of PI3K activation in reg
Externí odkaz:
https://doaj.org/article/dec485a01f5f4b86bd4a2ba118ff7c29
Autor:
Xi Wang, Brya G Matthews, Jungeun Yu, Sanja Novak, Danka Grcevic, Archana Sanjay, Ivo Kalajzic
Publikováno v:
JBMR Plus, Vol 3, Iss 5, Pp n/a-n/a (2019)
ABSTRACT BMPs are used in various clinical applications to promote bone formation. The limited success of the BMPs in clinical settings and supraphysiological doses required for their effects prompted us to evaluate the influence of other signaling m
Externí odkaz:
https://doaj.org/article/ca0c9b7a2d184a998b9ed0a5c19d928d
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223846 (2019)
Insufficient and delayed fracture healing remain significant public health problems with limited therapeutic options. Phosphoinositide 3-kinase (PI3K) signaling, a major pathway involved in regulation of fracture healing, promotes proliferation, migr
Externí odkaz:
https://doaj.org/article/382406ee55974948b1ca3c0d5d2de0b1
Autor:
Laura Doherty, Matthew Wan, Anna Peterson, Daniel W. Youngstrom, Justin S. King, Ivo Kalajzic, Kurt D. Hankenson, Archana Sanjay
Despite the remarkable regenerative capacity of skeletal tissues, nonunion of bone and failure of fractures to heal properly presents a significant clinical concern. Stem and progenitor cells are present in bone and become activated following injury;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d826d781ba55c235f83147f155cbb2
https://doi.org/10.1101/2022.12.09.519810
https://doi.org/10.1101/2022.12.09.519810
Publikováno v:
Bone.
Bone remodeling occurs through the interactions of three major cell lineages, osteoblasts, which mediates bone formation, osteocytes, which derive from osteoblasts, sense mechanical force and direct bone turnover, and osteoclasts, which mediate bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bffcf7b9146b9eff4965b4dac87bbe
https://pubmed.ncbi.nlm.nih.gov/34942359
https://pubmed.ncbi.nlm.nih.gov/34942359
Autor:
Vanessa Scanlon, Do Yu Soung, Naga Suresh Adapala, Elise Morgan, Marc F Hansen, Hicham Drissi, Archana Sanjay
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138194 (2015)
Mice in which Cbl is unable to bind PI3K (YF mice) display increased bone volume due to enhanced bone formation and repressed bone resorption during normal bone homeostasis. We investigated the effects of disrupted Cbl-PI3K interaction on fracture he
Externí odkaz:
https://doaj.org/article/73f71ab2ae8e4d8dafaf09d2c2491d1c
Publikováno v:
Bone
Effective bone resorption by osteoclasts is critical for balanced bone remodeling. We have previously reported that mice harboring a substitution mutation of tyrosine 737 to phenylalanine in the adapter protein Cbl (Cbl Y737F , YF) have increased bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7b35b5e5d59917dd18b8f800441922
https://doi.org/10.1016/j.bone.2019.07.009
https://doi.org/10.1016/j.bone.2019.07.009
Autor:
Dr. Archana Sanjay Desai
Education is one of the most effective force that can save our besieged environment. Environmental Ethics is the scientific study of various issues related to the rights of individual on the environment. It is the moral relationship of human beings w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9cebcd5e7586533090997f1b8e5867