Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Arben Nace"'
Autor:
Daniel Aldea, Blerina Kokalari, Yuji Atsuta, Heather L Dingwall, Ying Zheng, Arben Nace, George Cotsarelis, Yana G Kamberov
Publikováno v:
PLoS Genetics, Vol 19, Iss 2, p e1010614 (2023)
Enhancers are context-specific regulators of expression that drive biological complexity and variation through the redeployment of conserved genes. An example of this is the enhancer-mediated control of Engrailed 1 (EN1), a pleiotropic gene whose exp
Externí odkaz:
https://doaj.org/article/dc0bd058c24343faa8ee351712b38626
Autor:
Allen Oak, Chengxiang Fan, Ying Zheng, Arben Nace, Ruifeng Yang, Anisa Ray, Jen-Chih Hsieh, George Cotsarelis
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 23-23 (2023)
OBJECTIVES/GOALS: Current clinical practice recommends occlusive dressings (e.g., film and hydrocolloid) for wounds with variable regenerative capacities. However, clinical evidence suggests that occlusion may hinder regeneration. Our objective was t
Externí odkaz:
https://doaj.org/article/09f704f26f234c21b0ff4d7917b80a2d
Autor:
Daniel Aldea, Blerina Kokalari, Yuji Atsuta, Heather L. Dingwall, Ying Zheng, Arben Nace, George Cotsarelis, Yana G. Kamberov
SummaryEnhancers are context-specific regulators of expression that drive biological complexity and variation through the redeployment of conserved genes. An example of this is the enhancer-mediated control of the transcription of Engrailed 1 (EN1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cfff8cef2fed77f4aa195e7c60870db
https://doi.org/10.1101/2022.09.14.508033
https://doi.org/10.1101/2022.09.14.508033
Autor:
George Cotsarelis, Mingyao Li, Christian Hopkins, B. Kim, Jian Hu, Ruth Choa, Patrick Seale, Elizabeth A. Jacobsen, Arben Nace, John T. Seykora, Andy J. Minn, Mariko Okumura, Zoltan Arany, Garret A. FitzGerald, Shogo Wada, Hu Meng, Taku Kambayashi, Tanner F. Robertson, Ruth-Anne Langan Pai, Malay Haldar, Edward M. Behrens, Rebecca M. May, Junichiro Tohyama
Publikováno v:
Science
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Sweat out the fat with TSLP! Thymic stromal lymphopoietin (TSLP) is a cytokine that can promote immune responses that characterize allergic diseases. Choa et al . found that mice engineered to produce elevated TSLP displayed selective white adipose t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28009fce04a3ca9d720ff5e80907927c
https://europepmc.org/articles/PMC8917823/
https://europepmc.org/articles/PMC8917823/
Autor:
Ruth Choa, Junichiro Tohyama, Shogo Wada, Hu Meng, Mariko Okumura, Rebecca May, Tanner Robertson, Ruth-Anne Pai, Arben Nace, Christian Hopkins, Elizabeth Jacobsen, Malay Haldar, Garret FitzGerald, Edward Behrens, Andy Minn, Patrick Seale, George Cotsarelis, Brian Kim, John Seykora, Zoltan Arany, Taku Kambayashi
Publikováno v:
The Journal of Immunology. 206:113.01-113.01
Obesity is a serious public health concern. Emerging studies indicate that the immune system can regulate weight and energy homeostasis. Here we show that the cytokine Thymic Stromal Lymphopoietin (TSLP) stimulates T cells to induce selective white a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b34bfce5039406f632198d4bdb501148
https://doi.org/10.4049/jimmunol.206.supp.113.01
https://doi.org/10.4049/jimmunol.206.supp.113.01
Autor:
Ruth Choa, Shogo Wada, Hu Meng, Ruth-Anne Langan Pai, Mariko Okumura, Junichiro Tohyama, Arben Nace, Christian Hopkins, Malay Haldar, Patrick Seale, George Cotsarelis, John Seykora, Garret Fitzgerald, Zoltan Arany, Taku Kambayashi
Publikováno v:
The Journal of Immunology. 204:145.8-145.8
Within the past 30 years, obesity and associated disorders such as Type II diabetes are rapidly becoming world-wide epidemics. Type II diabetes, caused by the loss of insulin sensitivity, accounts for $327 billion annually in the U.S. Recent studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b178c0d44737699539d123be76b81ee3
https://doi.org/10.4049/jimmunol.204.supp.145.8
https://doi.org/10.4049/jimmunol.204.supp.145.8
Publikováno v:
Journal of Investigative Dermatology. 139:S160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d126995ea30a8ea15b95ec97f8f3048e
https://doi.org/10.1016/j.jid.2019.03.1001
https://doi.org/10.1016/j.jid.2019.03.1001
Autor:
David M. Ornitz, Phillip D. Holler, Oh Sang Kwon, Zhikun Zhang, George Cotsarelis, Maksim V. Plikus, Arben Nace, Sarah E. Millar, Xiaohong Zhang, Mayumi Ito, Sheena Baratono, Fen Wang, Michelle Spata, Chang D Kim, Elsa Treffeisen, Zaixin Yang
Publikováno v:
Nature Medicine. 19:916-923
Understanding molecular mechanisms for regeneration of hair follicles provides new opportunities for developing treatments for hair loss and other skin disorders. Here we show that fibroblast growth factor 9 (Fgf9), initially secreted by γδ T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f547421596d3c0583d754bc7b3923c9
https://doi.org/10.1038/nm.3181
https://doi.org/10.1038/nm.3181
Autor:
John Scholler, Joseph A. Fraietta, Shannon E. McGettigan, Avery D. Posey, Neeraja Idamakanti, Boris Engels, Prachi R. Patel, Andreas Loew, Christopher C. Kloss, Reshma Singh, Tucker Ezell, Akemi Kosaka, Hideho Okada, Taylor Chen, Alexandria P. Cogdill, Tzvete Dentchev, Arben Nace, Alina C. Boesteanu, Melissa Ramones, John T. Seykora, Jennifer Brogdon, Marcela V. Maus, Laura A. Johnson, Carl H. June, Na Li, Pramod Thekkat, Takayuki Ohkuri, Gabriela Plesa, Li Zhou
Publikováno v:
Science translational medicine, vol 7, iss 275
Chimeric antigen receptors (CARs) are synthetic molecules designed to redirect T cells to specific antigens. CAR-modified T cells can mediate long-term durable remissions in B cell malignancies, but expanding this platform to solid tumors requires th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10b2f8b186205e87d715f073694796e
https://escholarship.org/uc/item/6g44c974
https://escholarship.org/uc/item/6g44c974
Autor:
Wei Guo, Shujing Liu, Arben Nace, Ying Zheng, Meenhard Herlyn, George Cotsarelis, Ling Li, Michelle Burrows, Ruifeng Yang, Rutao Cui, Xiaowei Xu, Zhi Wei
Publikováno v:
Nature communications
Direct reprogramming provides a fundamentally new approach for the generation of patient-specific cells. Here, by screening a pool of candidate transcription factors, we identify that a combination of the three factors, MITF, SOX10 and PAX3, directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47793da11b8d20ded273698da1e2549b
https://doi.org/10.1038/ncomms6807
https://doi.org/10.1038/ncomms6807