Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Arbel D. Tadmor"'
Autor:
Gita Mahmoudabadi, Kelsey Homyk, Adam B. Catching, Ana Mahmoudabadi, Helen Bermudez Foley, Arbel D. Tadmor, Rob Phillips
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
Metagenomic studies have revolutionized the study of novel phages. However these studies trade depth of coverage for breadth. We show that the targeted sequencing of a small region of a phage terminase family can provide sufficient sequence diversity
Externí odkaz:
https://doaj.org/article/394e9a90a94e4a30a70d306ec98c79aa
Autor:
Barbara Schrörs, Sebastian Boegel, Christian Albrecht, Thomas Bukur, Valesca Bukur, Christoph Holtsträter, Christoph Ritzel, Katja Manninen, Arbel D. Tadmor, Mathias Vormehr, Ugur Sahin, Martin Löwer
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Tumor models are critical for our understanding of cancer and the development of cancer therapeutics. The 4T1 murine mammary cancer cell line is one of the most widely used breast cancer models. Here, we present an integrated map of the g
Externí odkaz:
https://doaj.org/article/a4d91ac8c0444717b82ad54389e39553
Autor:
Arbel D. Tadmor, Rob Phillips
Publikováno v:
Bioinformatics
Motivation Metagenomes offer a glimpse into the total genomic diversity contained within a sample. Currently, however, there is no straightforward way to obtain a non-redundant list of all putative homologs of a set of reference sequences present in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08610af968491373004f0ce7fc377a40
https://doi.org/10.1093/bioinformatics/btab703
https://doi.org/10.1093/bioinformatics/btab703
Autor:
Zhiqin Huang, Pramod K. Srivastava, Song Liu, Jason A. Greenbaum, Dirk Jäger, Jiaqian Wang, Ognjen Milicevic, Willem-Jan Krebber, Barbara Schrörs, Sean Michael Boyle, Michal Bassani-Sternberg, Ana M. Mijalkovic Lazic, Amit A. Lugade, Kristen K. Dang, Han Si, Alessandro Sette, Jeffrey P. Ward, Irsan Kooi, Michael F. Princiotta, Begonya Comin-Anduix, Thierry Schuepbach, Pia Kvistborg, Julia Kodysh, William Chour, Vladimir B. Kovacevic, Jan H. Kessler, Ariella Sasson, Antoni Ribas, Brian Stevenson, Sriram Sridhar, Prateek Tanden, Robert D. Schreiber, Jason Perera, Kathleen C. F. Sheehan, Hira Rizvi, Sachet A. Shukla, Baikang Pei, Han Chang, Bo Li, Ion I. Mandoiu, Cristina Puig-Saus, Beatriz M. Carreno, Si Qiu, Jennifer M. Shelton, Patrick Jongeneel, Qiang Hu, Taha Merghoub, Matthew D. Hellmann, James P. Conway, Francisco Arcila, Ton N. Schumacher, Mathias Vormehr, Christopher A. Morehouse, Patrice Manning, Jonathon Blake, Pornpimol Charoentong, Angela Frentzen, Christopher A. Miller, Michael A. Kuziora, Bin Song, Lei Wei, Martin Löwer, Gabor Bartha, Justin Guinney, Niels Halama, Rolf Hilker, Yinong Sebastian, Veliborka Josipovic, Jason Harris, Geng Liu, Guilhem Richard, Arjun A. Rao, Nikola M. Skundric, Markus Mueller, Daniel K. Wells, Tatiana Shcheglova, Inka Zörnig, Weixuan Fu, John Sidney, Nadine Defranoux, Gabriela Steiner, Joseph D. Szustakowski, Arbel D. Tadmor, Maxim N. Artyomov, Jianmin Wang, George Coukos, Brandon W. Higgs, Milica R. Kojicic, Siranush Sarkizova, Daphne van Beek, Naibo Yang, Robert Ziman, Mignonette H. Macabali, Thomas Yu, Nicolas Guex, Nina Bhardwaj, Lorenzo F. Fanchi, Bjoern Peters, Christian Iseli, Song Wu, Maren Lang, Juliet Forman, Marit M. van Buuren, David Balli, Steven L. C. Ketelaars, Nir Hacohen, Ekaterina Esaulova, Maarten Slagter, Todd Creasy, Robert A. Petit, Yi-Hsiang Hsu, Ravi Gupta, Katie M. Campbell, Pascal Gellert, David Haussler, Jesse M. Zaretsky, Sofie R. Salama, Vanessa M. Hubbard-Lucey, Joel Greshock, Zeynep Kosaloglu Yalcin, Cornelis J. M. Melief, Priyanka Shah, Ioannis Xenarios, Nevena M. Ilic Raicevic, Andrew Lamb, Suchit Jhunjhunwala, Aly A. Khan, David Gfeller, James R. Heath, Richard Chen, Jia M. Chen, Alphonsus H. C. Ng, Elham Sherafat, Ana Belen Blazquez, Leo J. Lee, Beata Berent-Maoz, Cheryl Selinsky, Jasreet Hundal, Eduardo Cortes, Xengie Doan, Sahar Al Seesi, Adam Kolom, Fred Ramsdell, Nicolas Robine, Andrew J. Rech
Many approaches to identify therapeutically relevant neoantigens couple tumor sequencing with bioinformatic algorithms and inferred rules of tumor epitope immunogenicity. However, there are no reference data to compare these approaches, and the param
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b788124c42a6ace5b9cb5efa2f3572c
https://resolver.caltech.edu/CaltechAUTHORS:20201019-121956456
https://resolver.caltech.edu/CaltechAUTHORS:20201019-121956456
Publikováno v:
Nature Biomedical Engineering. 2:566-569
Bringing truly personalized cancer vaccination with tumour neoantigens to the clinic will require overcoming the challenges of optimized vaccine design, manufacturing and affordability, and identification of the most suitable clinical setting.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2edc3ce93165c33b58b7ef6b3edc3f4b
https://doi.org/10.1038/s41551-018-0266-2
https://doi.org/10.1038/s41551-018-0266-2
Autor:
Jochen Utikal, Isabel Vogler, Özlem Türeci, Tana Omokoko, Christoph Höller, Matthias Miller, Björn-Philipp Kloke, Inga Ortseifer, Sebastian Attig, Goran Martic, Barbara Schrörs, Andrea Breitkreuz, Christoph Huber, Janina Buck, Valesca Bukur, Alexander Hohberger, Andreas Kuhn, Anna Paruzynski, Martina Zillgen, Meike Witt, Sandra Heesch, Jan Diekmann, Stefanie Bolte, Evelyna Derhovanessian, Christoffer Gebhardt, Ulrich Luxemburger, Alexandra-Kemmer Brück, Petra Simon, Arbel D. Tadmor, Patrick Sorn, Stephan Grabbe, Felicitas Müller, Sebastian Kreiter, Martin Suchan, David Langer, Mathias Vormehr, Christian Albrecht, Mustafa Diken, Eva Godehardt, Claudia Tolliver, Romina Nemecek, Martin Löwer, Katharina H Schreeb, Barbara Kasemann, Richard Rae, Carmen Loquai, Olga Waksmann, Andrée Rothermel, Ugur Sahin, Janko Ciesla
Publikováno v:
Nature. 547:222-226
T cells directed against mutant neo-epitopes drive cancer immunity. However, spontaneous immune recognition of mutations is inefficient. We recently introduced the concept of individualized mutanome vaccines and implemented an RNA-based poly-neo-epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb4ccb9b5ff2d67566919b8a33f73443
https://doi.org/10.1038/nature23003
https://doi.org/10.1038/nature23003
Autor:
Rob Phillips, Arbel D. Tadmor, Kelsey Homyk, Allison Cheung, Helen B. Foley, Gita Mahmoudabadi, Ana Mahmoudabadi, Adam Catching
Metagenomic studies have revolutionized the study of novel phages. However these studies trade the depth of coverage for breadth. In this study we show that the targeted sequencing of a phage genomic region as small as 200-300 base pairs, can provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26aa42117bcac4e8a7dd06abf24f593b
Autor:
Marij J. P. Welters, Dominik Maurer, Ulrik Lassen, Martin Löwer, Bernhard Rossler, Ugur Sahin, Andreas von Deimling, Toni Weinschenk, Christian H. Ottensmeier, Elisa Rusch, Colette Song, Valérie Dutoit, Jordi Rodon, Norbert Hilf, Hans Skovgaard Poulsen, Nina Pawlowski, Francisco Martínez-Ricarte, Judith R. Kroep, Juan Sahuquillo, Claudia Wagner, Edward W. Green, Sonja Dorner, Cedrik M. Britten, Franziska Hoffgaard, Jens Fritsche, Ghazaleh Tabatabai, Stefan Stevanovic, Harpreet Singh-Jasuja, Marco Skardelly, Sabrina Kuttruff-Coqui, Hans-Georg Rammensee, Katharina Kiesel, Alexander Ulges, Carsten Reinhardt, Michael Platten, Alexandra Kemmer-Brück, Bracha Shraibman, Denis Migliorini, Sebastian Kreiter, Jordi Piro, Oliver Schoor, Valesca Bukur, Katrin Frenzel, Berta Ponsati, David Capper, Jorg Ludwig, Monika Stieglbauer, Regina Mendrzyk, Miriam Meyer, Sjoerd H. van der Burg, Evelyna Derhovanessian, Pierre-Yves Dietrich, Arie Admon, Arbel D. Tadmor, Manja Idorn, Wolfgang Wick, Hideho Okada, Per thor Straten, Sandra Heesch, Lukas Bunse, Christoph Huber, Katy J. McCann, Cécile Gouttefangeas, John C. Castle
Publikováno v:
Nature, 565(7738), 240
Nature, Vol. 565, No 7738 (2019) pp. 240-245
Nature, Vol. 565, No 7738 (2019) pp. 240-245
Patients with glioblastoma currently do not sufficiently benefit from recent breakthroughs in cancer treatment that use checkpoint inhibitors1,2. For treatments using checkpoint inhibitors to be successful, a high mutational load and responses to neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b11cf9d2f3e8456103640b3a57a625
https://hdl.handle.net/1887/119498
https://hdl.handle.net/1887/119498
Autor:
Özlem Türeci, Christoph Huber, Jan Diekmann, Sebastian Kreiter, Sebastian Boegel, Niels van de Roemer, John C. Castle, Martin Löwer, Stephen P. Schoenberger, Fulvia Vascotto, Ugur Sahin, Mathias Vormehr, Mustafa Diken, Arbel D. Tadmor, Barbara Schrörs
Publikováno v:
Nature. 520:692-696
Tumour-specific mutations are ideal targets for cancer immunotherapy as they lack expression in healthy tissues and can potentially be recognized as neo-antigens by the mature T-cell repertoire. Their systematic targeting by vaccine approaches, howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b76ca4953d7bf7d51d96061cc55747
https://doi.org/10.1038/nature14426
https://doi.org/10.1038/nature14426
Autor:
Yuval Ebenstein, Deepak Kumar Sinha, Carole Gauron, Zhiping Feng, Arbel D. Tadmor, David Bensimon, Shuo Lin, Sophie Vriz, Bertrand Ducos, Lijun Xu, Thomas Le Saux, Shimon Weiss, Ludovic Jullien
Publikováno v:
Development. 139:3355-3362
All-trans retinoic acid (RA) is a key player in many developmental pathways. Most methods used to study its effects in development involve continuous all-trans RA activation by incubation in a solution of all-trans RA or by implanting all-trans RA-so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42075c148608d34d6cb15aa1eb9c7f7d
https://doi.org/10.1242/dev.077776
https://doi.org/10.1242/dev.077776