Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Araz, Marachelian"'
Autor:
Danny Lascano, Michael J. Zobel, William G. Lee, Stephanie Y. Chen, Abigail Zamora, Grace E. Asuelime, So Yung Choi, Antonios Chronopoulos, Shahab Asgharzadeh, Araz Marachelian, Jinseok Park, Michael A. Sheard, Eugene S. Kim
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract C–C motif chemokine ligand 2 (CCL2) is a monocyte chemoattractant that promotes metastatic disease and portends a poor prognosis in many cancers. To determine the potential of anti-CCL2 inhibition as a therapy for recurrent metastatic dise
Externí odkaz:
https://doaj.org/article/179f9be33fdc468ab4b9283cf07129ea
Autor:
Esther R. Berko, Gabriela M. Witek, Smita Matkar, Zaritza O. Petrova, Megan A. Wu, Courtney M. Smith, Alex Daniels, Joshua Kalna, Annie Kennedy, Ivan Gostuski, Colleen Casey, Kateryna Krytska, Mark Gerelus, Dean Pavlick, Susan Ghazarian, Julie R. Park, Araz Marachelian, John M. Maris, Kelly C. Goldsmith, Ravi Radhakrishnan, Mark A. Lemmon, Yaël P. Mossé
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Activating point mutations in Anaplastic Lymphoma Kinase (ALK) have positioned ALK as the only mutated oncogene tractable for targeted therapy in neuroblastoma. Cells with these mutations respond to lorlatinib in pre-clinical studies, provid
Externí odkaz:
https://doaj.org/article/c0e4bcb6136d4cc7a5072df22f3d7275
Autor:
Kelly C. Goldsmith, Julie R. Park, Kimberly Kayser, Jemily Malvar, Yueh-Yun Chi, Susan G. Groshen, Judith G. Villablanca, Kateryna Krytska, Lillian M. Lai, Patricia T. Acharya, Fariba Goodarzian, Bruce Pawel, Hiroyuki Shimada, Susan Ghazarian, Lisa States, Lynley Marshall, Louis Chesler, Meaghan Granger, Ami V. Desai, Rajen Mody, Daniel A. Morgenstern, Suzanne Shusterman, Margaret E. Macy, Navin Pinto, Gudrun Schleiermacher, Kieuhoa Vo, Holger C. Thurm, Joseph Chen, Marlon Liyanage, Gerson Peltz, Katherine K. Matthay, Esther R. Berko, John M. Maris, Araz Marachelian, Yael P. Mossé
Publikováno v:
Nature Medicine. 29:1092-1102
Neuroblastomas harbor ALK aberrations clinically resistant to crizotinib yet sensitive pre-clinically to the third-generation ALK inhibitor lorlatinib. We conducted a first-in-child study evaluating lorlatinib with and without chemotherapy in childre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05cb1069b5caae85576f8251b56aaa50
https://doi.org/10.1038/s41591-023-02297-5
https://doi.org/10.1038/s41591-023-02297-5
Autor:
Kevin Campbell, Susan Groshen, Angela C. Evans, Stephen Wilson, Aimy Sebastian, Gabriela G. Loots, Araz Marachelian, Myriam Armant, Sharmistha Pal, Daphne A. Haas-Kogan, Julie R. Park, Meaghan Granger, Katherine K. Matthay, Matthew A. Coleman, Steven G. DuBois
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:1115-1128
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed9bb2e21be600a1d207d8917ee17e00
https://doi.org/10.1016/j.ijrobp.2022.11.045
https://doi.org/10.1016/j.ijrobp.2022.11.045
Publikováno v:
Journal of Clinical and Translational Science, Vol 5, Pp 101-101 (2021)
ABSTRACT IMPACT: Preliminary results will inform the formal evaluation of the reliability of point-of-care ultrasound (POCUS) done by the gastroenterologist compared to standard of care methods such as MR-Enterography. OBJECTIVES/GOALS: Evaluation of
Externí odkaz:
https://doaj.org/article/bd3943ffe7cb475a89b17d4cf59160ef
Autor:
Araz Marachelian, Katherine K. Matthay, Denice Tsao-Wei, Chunqiao Luo, Scarlett Czarnecki, Najee Boucher, Hiroyuki Shimada, Fariba Goodarzian, Hollie Lai, Jesse Courtier, Randall Hawkins, Lars M. Wagner, Greg Yanik, Susan L. Cohn, Margaret E. Macy, Julie R. Park, Brian Weiss, M. Meaghan Granger, Kelly Goldsmith, Clare J. Twist, John M. Maris, Rochelle Bagatell, Susan Groshen, Renee McGovern, Joel M. Reid, Rachel A. Kudgus, Elizabeth Fox, Yael P. Mosse, Steven G. DuBois
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f9c0236f5d8ab34c60e9edd6137a2d
https://doi.org/10.1158/1078-0432.22469513.v1
https://doi.org/10.1158/1078-0432.22469513.v1
Autor:
Araz Marachelian, Katherine K. Matthay, Denice Tsao-Wei, Chunqiao Luo, Scarlett Czarnecki, Najee Boucher, Hiroyuki Shimada, Fariba Goodarzian, Hollie Lai, Jesse Courtier, Randall Hawkins, Lars M. Wagner, Greg Yanik, Susan L. Cohn, Margaret E. Macy, Julie R. Park, Brian Weiss, M. Meaghan Granger, Kelly Goldsmith, Clare J. Twist, John M. Maris, Rochelle Bagatell, Susan Groshen, Renee McGovern, Joel M. Reid, Rachel A. Kudgus, Elizabeth Fox, Yael P. Mosse, Steven G. DuBois
Supplemental Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd4fef903a7a83553b2ad1b6b1ee58b
https://doi.org/10.1158/1078-0432.22469510.v1
https://doi.org/10.1158/1078-0432.22469510.v1
Autor:
Katherine K. Matthay, Araz Marachelian, Judith G. Villablanca, Denice Tsao-Wei, Scarlett Czarnecki, Hiroyuki Shimada, Fariba Goodarzian, Hollie Jackson, Jesse Courtier, Randall Hawkins, Gregory A. Yanik, M. Meaghan Granger, Susan L. Cohn, Brian Weiss, Kathy Giacomini, Eugene Chen, Ethan Geier, Xiaodong Yang, Daphne A. Haas-Kogan, Julie R. Park, Susan Groshen, Steven G. DuBois
Purpose: 131I-metaiodobenzylguanidine (MIBG) is a radiopharmaceutical with activity in neuroblastoma. Vorinostat is a histone deacetylase inhibitor that has radiosensitizing properties. The goal of this phase I study was to determine the MTDs of vori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3554100df37e38a8e97ee7720709512e
https://doi.org/10.1158/1078-0432.c.6524513
https://doi.org/10.1158/1078-0432.c.6524513
Autor:
Araz Marachelian, Katherine K. Matthay, Denice Tsao-Wei, Chunqiao Luo, Scarlett Czarnecki, Najee Boucher, Hiroyuki Shimada, Fariba Goodarzian, Hollie Lai, Jesse Courtier, Randall Hawkins, Lars M. Wagner, Greg Yanik, Susan L. Cohn, Margaret E. Macy, Julie R. Park, Brian Weiss, M. Meaghan Granger, Kelly Goldsmith, Clare J. Twist, John M. Maris, Rochelle Bagatell, Susan Groshen, Renee McGovern, Joel M. Reid, Rachel A. Kudgus, Elizabeth Fox, Yael P. Mosse, Steven G. DuBois
Purpose:In phase I testing, alisertib tablets with irinotecan and temozolomide showed significant antitumor activity in patients with neuroblastoma. This study sought to confirm activity of this regimen; evaluate an alisertib oral solution; and evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2485f3121b3fe9d725c459bf2c01de63
https://doi.org/10.1158/1078-0432.c.6527279.v1
https://doi.org/10.1158/1078-0432.c.6527279.v1
Autor:
Robert C. Seeger, Richard Sposto, Shahab Asgharzadeh, Susan Groshen, Katherine K. Matthay, Meaghan Granger, Kelly Goldsmith, Brian D. Weiss, Rebekah Kennedy, Scarlett Czarnecki, Sabrina Young, Nora Bedrossian, Richard Gallego, Jaime A. Parra, Hung C. Tran, Hiroyuki Shimada, Hollie A. Lai, Fariba Goodarzian, Betty Liu, Cathy W. Liu, Judith G. Villablanca, Araz Marachelian
Supplementary Figure Legends for A1-A3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00dce7f361a6740c645a34524574b2e8
https://doi.org/10.1158/1078-0432.22467864
https://doi.org/10.1158/1078-0432.22467864