Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Aravinda M. de Silva"'
Autor:
Teresa C. Smith, Daniel O. Espinoza, Yerun Zhu, Jaime A. Cardona-Ospina, Natalie M. Bowman, Sylvia Becker-Dreps, Nadine Rouphael, Alfonso J. Rodriguez-Morales, Filemon Bucardo, Srilatha Edupuganti, Lakshmanane Premkumar, Mark J. Mulligan, Aravinda M. de Silva, Matthew H. Collins
Publikováno v:
EBioMedicine, Vol 98, Iss , Pp 104875- (2023)
Summary: Background: Autochthonous transmission of Zika virus (ZIKV) has been reported in 87 countries since 2015. Although most infections are mild, there is risk of Guillain-Barré syndrome and adverse pregnancy outcomes. Vaccines are urgently need
Externí odkaz:
https://doaj.org/article/5465d21883fc4ebaa927c21e1dac60cb
Autor:
Cameron Adams, Ramesh Jadi, Bruno Segovia-Chumbez, Jedas Daag, Michelle Ylade, Freddy A. Medina, Tyler M. Sharp, Jorge L. Munoz-Jordan, In-Kyu Yoon, Jacqueline Deen, Anna Lena Lopez, Aravinda M. de Silva, Lakshmanane Premkumar
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 12, Pp 3073-3081 (2021)
Zika virus (ZIKV) is a member of the Flaviviridae family, which includes other clinically notable viruses such as the 4 dengue virus serotypes (DENV-1–4). Distinguishing DENVs from ZIKV using the established serologic assays widely used for monitor
Externí odkaz:
https://doaj.org/article/dc3f161b10e44300a1e07f7361479c9c
Autor:
Mahesha N. Nadugala, Chandima Jeewandara, Ramesh S. Jadi, Gathsaurie N. Malavige, Aravinda M. de Silva, Prasad H. Premaratne, Charitha L. Goonasekara
Publikováno v:
BMC Immunology, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background The natural antibody responses to B-cell epitopes from dengue structural proteins were assessed using immune sera from people having well-defined past dengue infections with one of the four serotypes. Method Based on an immune-com
Externí odkaz:
https://doaj.org/article/62cb0d3bee6147188c7afeb6f4b99cde
Autor:
Luther A. Bartelt, Alena J. Markmann, Bridget Nelson, Jessica Keys, Heather Root, Heather I. Henderson, JoAnn Kuruc, Caroline Baker, D. Ryan Bhowmik, Yixuan J. Hou, Lakshmanane Premkumar, Caleb Cornaby, John L. Schmitz, Susan Weiss, Yara Park, Ralph Baric, Aravinda M. de Silva, Anne Lachiewicz, Sonia Napravnik, David van Duin, David M. Margolis
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT COVID-19 convalescent plasma (CCP) was an early and widely adopted putative therapy for severe COVID-19. Results from randomized control trials and observational studies have failed to demonstrate a clear therapeutic role for CCP for severe
Externí odkaz:
https://doaj.org/article/30319211eb6a4c8d9594c677f95587db
Autor:
Longping V. Tse, Rita M. Meganck, Stephanie Dong, Lily E. Adams, Laura J. White, Michael L. Mallory, Ramesh Jadi, Aravinda M. de Silva, Ralph S. Baric
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Maturation of dengue viruses (DENVs) alters the structure, immunity, and infectivity of the virion and highly mature particles represent the dominant form in vivo. The production of highly mature virions principally relies on the structure a
Externí odkaz:
https://doaj.org/article/60abca8488114aa194c89a1d68e2e9f3
Autor:
Cesar A. Lopez, Clark H. Cunningham, Sierra Pugh, Katerina Brandt, Usaphea P. Vanna, Matthew J. Delacruz, Quique Guerra, D. Ryan Bhowmik, Samuel J. Goldstein, Yixuan J. Hou, Margaret Gearhart, Christine Wiethorn, Candace Pope, Carolyn Amditis, Kathryn Pruitt, Cinthia Newberry-Dillon, John L. Schmitz, Lakshmanane Premkumar, Adaora A. Adimora, Ralph S. Baric, Michael Emch, Ross M. Boyce, Allison E. Aiello, Bailey K. Fosdick, Daniel B. Larremore, Aravinda M. de Silva, Jonathan J. Juliano, Alena J. Markmann
Publikováno v:
mSphere, Vol 7, Iss 3 (2022)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of deaths around the world within the past 2 years. Transmission within the United States has been heterogeneously distributed by geography and social factors w
Externí odkaz:
https://doaj.org/article/f90bbb5227dc48ee91cfe5a8e9c264aa
Autor:
Usha K. Nivarthi, Jesica Swanstrom, Matthew J. Delacruz, Bhumi Patel, Anna P. Durbin, Steve S. Whitehead, Beth D. Kirkpatrick, Kristen K. Pierce, Sean A. Diehl, Leah Katzelnick, Ralph S. Baric, Aravinda M. de Silva
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Multivalent vaccines that confer protection to multiple serotypes of Dengue virus have been established. Here the authors examine the presence of vaccine induced multivalent antibodies and how these link to protection in a human challenge model of De
Externí odkaz:
https://doaj.org/article/3754cf1077b043a0a2eef363edc7666d
Autor:
Omar Zepeda, Daniel O. Espinoza, Evelin Martinez, Kaitlyn A. Cross, Sylvia Becker-Dreps, Aravinda M. de Silva, Natalie M. Bowman, Lakshmanane Premkumar, Elizabeth M. Stringer, Filemón Bucardo, Matthew H. Collins
Publikováno v:
Viruses, Vol 15, Iss 3, p 796 (2023)
Objective: To understand the dynamics of Zika virus (ZIKV)-specific antibody immunity in children born to mothers in a flavivirus-endemic region during and after the emergence of ZIKV in the Americas. Methods: We performed serologic testing for ZIKV
Externí odkaz:
https://doaj.org/article/f5aef308e15c495daf2ebb2670dfef55
Autor:
Hasitha A. Tissera, Bernard D.W. Jayamanne, Rajendra Raut, Sakunthala M.D. Janaki, Yesim Tozan, Preshila C. Samaraweera, Prasad Liyanage, Azhar Ghouse, Chaturaka Rodrigo, Aravinda M. de Silva, Sumadhya D. Fernando
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 4, Pp 682-691 (2020)
In 2017, a dengue epidemic of unexpected magnitude occurred in Sri Lanka. A total of 186,101 suspected cases and 440 dengue-related deaths occurred. We conducted a comprehensive analysis of this epidemic by comparing national surveillance data for 20
Externí odkaz:
https://doaj.org/article/095eed7c9a064ce389768cba303c65e2
Autor:
Heather B. Root, Matt Gilleskie, Chih-Huan Lu, Andrew Gilmore, Mariama Evans, Bridget G. Nelson, William Johnson, Brian Gurney, JoAnn Kuruc, Alena J. Markmann, Amir H. Barzin, David A. Wohl, William A. Fischer, Yara A. Park, Susan Weiss, Sonia Napravnik, Ralph Baric, Aravinda M. de Silva, Anne M. Lachiewicz, David van Duin, David M. Margolis, Michael E. Herce, Luther A. Bartelt
Publikováno v:
PLoS ONE, Vol 17, Iss 12 (2022)
Amidst the therapeutic void at the onset of the COVID-19 pandemic, a critical mass of scientific and clinical interest coalesced around COVID-19 convalescent plasma (CCP). To date, the CCP literature has focused largely on safety and efficacy outcome
Externí odkaz:
https://doaj.org/article/dea6d94224054a2c874343f3981d4cb1