Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Aravind R. Gade"'
Autor:
Yuling Han, Jiajun Zhu, Liuliu Yang, Benjamin E. Nilsson-Payant, Romulo Hurtado, Lauretta A. Lacko, Xiaolu Sun, Aravind R. Gade, Christina A. Higgins, Whitney J. Sisso, Xue Dong, Maple Wang, Zhengming Chen, David D. Ho, Geoffrey S. Pitt, Robert E. Schwartz, Benjamin R. tenOever, Todd Evans, Shuibing Chen
Publikováno v:
Circulation Research. 130:963-977
Background: Increasing evidence suggests that cardiac arrhythmias are frequent clinical features of coronavirus disease 2019 (COVID-19). Sinus node damage may lead to bradycardia. However, it is challenging to explore human sinoatrial node (SAN) path
Autor:
Karan H. Muchhala, Eda Koseli, Aravind R. Gade, Kareem Woods, Suha Minai, Minho Kang, A Rory McQuiston, William L. Dewey, Hamid I. Akbarali
Publikováno v:
J Neuroimmune Pharmacol
The gastrointestinal epithelium is critical for maintaining a symbiotic relationship with commensal microbiota. Chronic morphine exposure can compromise the gut epithelial barrier in mice and lead to dysbiosis. Recently, studies have implicated morph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474271ff440659006813732d4a10e2c2
https://europepmc.org/articles/PMC9343479/
https://europepmc.org/articles/PMC9343479/
Publikováno v:
The Journal of General Physiology
The auxiliary proteins CaM and FHF bind to the C-terminal domain of voltage-gated sodium channels to limit the persistent inward currents associated with cardiac arrhythmias. Gade et al. reveal that CaM and FHF exert their effects by stabilizing an i
Autor:
Minho Kang, Aravind R. Gade, William L. Dewey, Kurt F. Hauser, Sukhada Bhave, Hamid I. Akbarali
Publikováno v:
The FASEB Journal. 31:2649-2660
Morphine is one of the most widely used drugs for the treatment of pain. However, side effects, including persistent constipation and antinociceptive tolerance, limit its clinical efficacy. Prolonged morphine treatment results in a “leaky” gut, p
Autor:
Geoffrey S. Pitt, Aravind R. Gade, Xiaolu Sun, Daniel S. Sinden, David E. Cohen, Curtis J. Bare, Corey D. Holman
Fibroblast growth factor (FGF)13, a nonsecreted, X-linked, FGF homologous factor, is differentially expressed in adipocytes in response to diet, yet Fgf13’s role in metabolism has not been explored. Heterozygous Fgf13 knockouts fed normal chow and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391c6bb6dad38bbcfaf6dbdc7e3bd37a
https://europepmc.org/articles/PMC6994920/
https://europepmc.org/articles/PMC6994920/
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 308:G532-G539
Hydrogen sulfide (H2S) is an endogenous gaseous mediator affecting many physiological and pathophysiological conditions. Enhanced expression of H2S and reactive nitrogen/oxygen species (RNS/ROS) during inflammation alters cellular excitability via mo
Publikováno v:
Molecular Pharmacology. 83:294-306
The ATP-sensitive potassium channel (K(ATP)) in mouse colonic smooth muscle cell is a complex containing a pore-forming subunit (Kir6.1) and a sulfonylurea receptor subunit (SUR2B). These channels contribute to the cellular excitability of smooth mus
Autor:
John R. Grider, Fayez A. Khan, M. Imad Damaj, Hamid I. Akbarali, Aravind R. Gade, Minho Kang, William L. Dewey
Opioid-induced constipation is a major side effect that persists with long-term opioid use. Previous studies demonstrated that nicotine-induced contractions are enhanced after long-term morphine exposure in guinea pig ileum. In the present study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7b886e669c3f8a1a7f5f7f1f975b2b
https://europepmc.org/articles/PMC4885510/
https://europepmc.org/articles/PMC4885510/
Publikováno v:
The FASEB Journal. 29
Autor:
Sukhada Bhave, Hamid I. Akbarali, William L. Dewey, Karan H. Muchhala, Minho Kang, Essie Komla, Kensuke Sakakibara, Aravind R. Gade, Ryan A. Mischel
Publikováno v:
Gastroenterology. 150:S594-S595