Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Aravind, Cherukuri"'
Autor:
Aravind, Cherukuri, David M, Rothstein
Publikováno v:
Current Opinion in Organ Transplantation. 27:385-391
Regulatory B cells (Bregs) play a prominent role in various disease settings. While progress has been hindered by the lack of a specific Breg marker, new findings highlight their role modulating the alloimmune response and promoting allograft surviva
Autor:
Akhil Sharma, MD, Aravind Cherukuri, MD, PhD, Rajil B. Mehta, MD, Puneet Sood, MD, Sundaram Hariharan, MD
Publikováno v:
Transplantation Direct, Vol 5, Iss 2, p e424 (2019)
Background. High calcineurin inhibitor (CNI) intrapatient variability (IPV) has been associated with poor kidney allograft outcomes. However, the relationship between early allograft histological changes, their progression, and CNI-IPV is less well s
Externí odkaz:
https://doaj.org/article/f44e078390ee43f1b6f9cbaa22ac8e8b
Autor:
Charbel Elias, Aravind Cherukuri
Publikováno v:
Transplantation.
Autor:
Aravind Cherukuri, Khodor I. Abou-Daya, Raad Chowdhury, Rajil B. Mehta, Sundaram Hariharan, Parmjeet Randhawa, David M. Rothstein
Publikováno v:
Kidney international.
Borderline rejection (BL) in renal transplantation is associated with decreased allograft survival, yet many patients with BL maintain stable graft function. Identifying patients with early BL at-risk for shortened allograft survival would allow for
Publikováno v:
Immunological reviews
Regulatory B cells (Bregs) ameliorate autoimmune disease and prevent allograft rejection. Conversely, they hinder effective clearance of pathogens and malignancies. Breg activity is mainly attributed to IL-10 expression, but also utilizes additional
Autor:
Johnny Bou Saba, Aravind Cherukuri
Publikováno v:
Kidney international. 102(2)
In this issue, Burton et al. describe a convincing method to identify and enumerate human leukocyte antigen-specific B cells and subsets using biotinylated human leukocyte antigen proteins. Importantly, they demonstrate that these antigen-specific B
401.3: Microvascular Inflammation in Renal Transplant Recipients Without Antibody Mediated Rejection
Publikováno v:
Transplantation. 106:S374-S374
Autor:
Aravind Cherukuri, Rajil Mehta, Amit D. Tevar, Akhil Sharma, Adriana Zeevi, Puneet Sood, David M. Rothstein, Sundaram Hariharan
Publikováno v:
Kidney International. 96:202-213
Post-transplant donor specific antibody (DSA) is associated with poor renal allograft outcomes. However, variable timing of DSA assessment and inclusion of patients who undergo desensitization treatments have hindered our understanding of its consequ
Publikováno v:
Clin Lab Med
B cells shape the alloimmune response through polarized subsets. These cells inhibit or promote immune responses by expressing suppressive or proinflammatory cytokines. Their summed activity dictates the influence of B cells on the alloimmune respons
Autor:
Richard Baker, Aravind Cherukuri, Kanishka Mohib, Amit D. Tevar, David M. Rothstein, Sundaram Hariharan, Hans J. Stauss, M Harber, Leting Zheng, Douglas Landsittel, Ciara N. Magee, Fadi G. Lakkis, Rajil Mehta, Alan D. Salama
Publikováno v:
Science Translational Medicine. 13
Early immunological biomarkers that predict rejection and chronic allograft loss are needed to inform preemptive therapy and improve long-term outcomes. Here, we prospectively examined the ratio of interleukin-10 (IL-10) to tumor necrosis factor-α (