Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Arati S Desai"'
Autor:
Igor Makhlin, Ryan D Salinas, Daniel Zhang, Fadi Jacob, Gou-li Ming, Hongjun Song, Deeksha Saxena, Jay F Dorsey, MacLean P Nasrallah, Jennifer JD Morrissette, Zev A Binder, Donald M O'Rourke, Arati S Desai, Steven Brem, Stephen J Bagley
Publikováno v:
CNS Oncology, Vol 8, Iss 3 (2019)
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and carries a dismal prognosis. The EGFR gene is among the most commonly deranged genes in GBM and thus an important therapeutic target. We report the case of a young femal
Externí odkaz:
https://doaj.org/article/03959e296e524237be76b58b81c7e0c8
Autor:
Spyridon Bakas, Chiharu Sako, Hamed Akbari, Michel Bilello, Aristeidis Sotiras, Gaurav Shukla, Jeffrey D. Rudie, Natali Flores Santamaría, Anahita Fathi Kazerooni, Sarthak Pati, Saima Rathore, Elizabeth Mamourian, Sung Min Ha, William Parker, Jimit Doshi, Ujjwal Baid, Mark Bergman, Zev A. Binder, Ragini Verma, Robert A. Lustig, Arati S. Desai, Stephen J. Bagley, Zissimos Mourelatos, Jennifer Morrissette, Christopher D. Watt, Steven Brem, Ronald L. Wolf, Elias R. Melhem, MacLean P. Nasrallah, Suyash Mohan, Donald M. O’Rourke, Christos Davatzikos
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-12 (2022)
Measurement(s) Magnetic Resonance Imaging Technology Type(s) Magnetic Resonance Imaging of the Brain with and without Contrast Sample Characteristic - Organism Homo sapiens Sample Characteristic - Environment brain Sample Characteristic - Location Un
Externí odkaz:
https://doaj.org/article/5d5b415e3a86419991ae9fdec07415bc
Autor:
Anahita Fathi Kazerooni, Sanjay Saxena, Erik Toorens, Danni Tu, Vishnu Bashyam, Hamed Akbari, Elizabeth Mamourian, Chiharu Sako, Costas Koumenis, Ioannis Verginadis, Ragini Verma, Russell T. Shinohara, Arati S. Desai, Robert A. Lustig, Steven Brem, Suyash Mohan, Stephen J. Bagley, Tapan Ganguly, Donald M. O’Rourke, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Multi-omic data, i.e., clinical measures, radiomic, and genetic data, capture multi-faceted tumor characteristics, contributing to a comprehensive patient risk assessment. Here, we investigate the additive value and independent reproducibili
Externí odkaz:
https://doaj.org/article/2e0a631fb2f84bd8ab1d9f8f31d56f26
Autor:
Joseph S. Durgin, Fraser Henderson, MacLean P. Nasrallah, Suyash Mohan, Sumei Wang, Simon F. Lacey, Jan Joseph Melenhorst, Arati S. Desai, John Y. K. Lee, Marcela V. Maus, Carl H. June, Steven Brem, Roddy S. O’Connor, Zev Binder, Donald M. O’Rourke
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Autologous chimeric antigen receptor (CAR) T cells targeted to epidermal growth factor receptor variant III (CAR T-EGFRvIII) have been developed and administered experimentally to treat patients with IDH1 wildtype recurrent glioblastoma (rGBM) (NCT02
Externí odkaz:
https://doaj.org/article/28e7edd3d6b7457386c94ed075c82476
Autor:
Erica L. Carpenter, Arati S. Desai, Steven Brem, Andrew J. Cucchiara, Donald M. O'Rourke, Zev A. Binder, Jennifer J.D. Morrissette, MacLean P. Nasrallah, Stephanie S. Yee, Theresa Christensen, Samantha Guiry, Timothy Prior, Jasmin Hussain, Whitney Sarchiapone, Scott Levy, Jeffrey B. Ware, Jacob E. Till, Jazmine J. Mays, S. Ali Nabavizadeh, Stephen J. Bagley
Tissue fusion transcript panel gene coverage (55 genes)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19638daa588e5670ddaf2cec5bd2e0d5
https://doi.org/10.1158/1078-0432.22477848.v1
https://doi.org/10.1158/1078-0432.22477848.v1
Autor:
Erica L. Carpenter, Arati S. Desai, Steven Brem, Andrew J. Cucchiara, Donald M. O'Rourke, Zev A. Binder, Jennifer J.D. Morrissette, MacLean P. Nasrallah, Stephanie S. Yee, Theresa Christensen, Samantha Guiry, Timothy Prior, Jasmin Hussain, Whitney Sarchiapone, Scott Levy, Jeffrey B. Ware, Jacob E. Till, Jazmine J. Mays, S. Ali Nabavizadeh, Stephen J. Bagley
Purpose:The clinical utility of plasma cell-free DNA (cfDNA) has not been assessed prospectively in patients with glioblastoma (GBM). We aimed to determine the prognostic impact of plasma cfDNA in GBM, as well as its role as a surrogate of tumor burd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a91c2d19a3301d7ef331635b3e66b0
https://doi.org/10.1158/1078-0432.c.6529773
https://doi.org/10.1158/1078-0432.c.6529773
Autor:
Erica L. Carpenter, Arati S. Desai, Steven Brem, Andrew J. Cucchiara, Donald M. O'Rourke, Zev A. Binder, Jennifer J.D. Morrissette, MacLean P. Nasrallah, Stephanie S. Yee, Theresa Christensen, Samantha Guiry, Timothy Prior, Jasmin Hussain, Whitney Sarchiapone, Scott Levy, Jeffrey B. Ware, Jacob E. Till, Jazmine J. Mays, S. Ali Nabavizadeh, Stephen J. Bagley
Plasma cell-free DNA (cfDNA) concentration (ng/mL) is correlated with (A), total radiographic tumor burden (contrast-enhancing tumor + T2/FLAIR non-enhancing tumor) and (B), contrast-enhancing tumor burden at the first post-radiation MRI scan in pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba4638fe7aa521e90713a9067acdfb2
https://doi.org/10.1158/1078-0432.22477854
https://doi.org/10.1158/1078-0432.22477854
Autor:
Stephen J. Bagley, Zev A. Binder, Arati S. Desai, Maclean P. Nasrallah, Eileen Maloney, Steven Brem, Robert Lustig, Goldie Kurtz, Michelle Alonso-Basanta, Suyash Mohan, Wei-Ting Hwang, Oliver Y. Tang, Meghan Logun, Meghna Bhattacharyya, Kelly Markowitz, Devora Delman, Amy Marshall, Cecile Alanio, Gregory L. Beatty, Jennifer L. Brogdon, Elizabeth Hexner, Donald M. O'Rourke
Treatment efficacy with chimeric antigen receptor (CAR) T cell therapy in glioblastoma (GBM) is undermined by an immunosuppressive tumor microenvironment (TME). We previously showed that CAR T cell therapy targeting epidermal growth factor receptor v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91a30f0fa5828a2c7ff7e2eb9c340b21
https://doi.org/10.21203/rs.3.rs-2742648/v1
https://doi.org/10.21203/rs.3.rs-2742648/v1
Autor:
Lauren Reed-Guy, Arati S Desai, Richard E Phillips, Desiree Croteau, Karen Albright, Meghan O’Neill, Steven Brem, Donald M O’Rourke, Nduka M Amankulor, Stephen J Bagley
Publikováno v:
Neuro Oncol
Background Glioblastoma (GBM) is associated with a high incidence of venous thromboembolism (VTE), but there are little data to guide anticoagulation in patients with GBM, in whom the risks of VTE must be balanced against the risk of intracranial hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd3ff495bae2924e99402758b65f2d6
https://doi.org/10.1093/neuonc/noac125
https://doi.org/10.1093/neuonc/noac125
Autor:
Robert D. Schwab, Stephen Bagley, Zev Binder, Robert Lustig, Donald O’Rourke, Steven Brem, Arati S. Desai, MacLean Nasrallah
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 45-45 (2018)
OBJECTIVES/SPECIFIC AIMS: In patients with recurrent glioblastoma (GBM) who undergo a second surgery following standard chemoradiotherapy, histopathologic examination of the resected tissue often reveals a combination of viable tumor and treatment-re
Externí odkaz:
https://doaj.org/article/d5fb791f26ca4bae9b539b7ae80dfd0e