Výsledky vyhledávání - "Arati D. Naik"

Non-destructive and Selective Imaging of the Functionally Active, Pro-invasive Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Enzyme in Cancer Cells

Autor: Amolkumar Karwa, Carolyn J. Sympson, Michael A. Brown, John N. Freskos, Vladislav S. Golubkov, Carol Pearcy Howard, Arati D. Naik, Sergey A. Shiryaev, Alex Y. Strongin, Albert G. Remacle

Publikováno v: Journal of Biological Chemistry. 288:20568-20580

Proteolytic activity of cell surface-associated MT1-matrix metalloproteinase (MMP) (MMP-14) is directly related to cell migration, invasion, and metastasis. MT1-MMP is regulated as a proteinase by activation and conversion of the latent proenzyme int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a713a9cfe3b9733c8698dcc9f7719d93
https://doi.org/10.1074/jbc.m113.471508

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Noninvasive imaging of cell death using an Hsp90 ligand

Autor: Danielle Park, Christine L. Hemenway, Amol Karwa, Beth Warner, Tania Massamiri, Lori K. Chinen, Arati D. Naik, Jan MacDonald, Pierre J. Dilda, Philip J. Hogg, Kah Tiong Kuan, Kevin Camphausen, Jason W. H. Wong, Anthony S. Don, Mary Dyszlewski

Publikováno v: J Am Chem Soc

Cell death plays a central role in normal physiology and in disease. Common to apoptotic and necrotic cell death is the eventual loss of plasma membrane integrity. We have produced a small organoarsenical compound, 4-(N-(S-glutathionylacetyl)amino)ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a458c6ed33823ccadcaccddeb1a9e6b3
https://pubmed.ncbi.nlm.nih.gov/21322555

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Abstract 5287: Non-invasive imaging of tumor cell death using a Hsp90 ligand

Autor: Philip J. Hogg, Christine L. Hemenway, Tania Massamiri, Lori Chinen, Danielle Park, Beth Warner, Pierre J. Dilda, Mary Dyszlewski, Anthony S. Don, Amol Karwa, Jason W. H. Wong, Kah-Tiong Kuan, Arati D. Naik

Publikováno v: Cancer Research. 71:5287-5287

Cell death plays an integral role in physiology, including turnover of cells in the gastrointestinal tract, the menstrual cycle and the immune system. Imbalance of this process is also associated with disease. Excessive cell death is characteristic o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa93f9ca38e29ee8ef2e2f2a6a09c783
https://doi.org/10.1158/1538-7445.am2011-5287

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