Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Arata, Shimo"'
Autor:
Yusuke Nakamura, Soo Chin Lee, Ching-Wan Chan, Mikael Hartman, Ern Yu Tan, Arata Shimo, Koichiro Tsugawa, Daisuke Shimizu, Kazuhiro Shimada, Akimitsu Yamada, Shinichi Baba, Yasuaki Sagara, Ayami Matsukata, Mai Onomura, Hisamitsu Zaha, Minoru Okazaki, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Yoshie Hasegawa, Hiroshi Matsumoto, Kana Miyahara, Takashi Ishikawa, Hiroyuki Takei, Tomoko Takamaru, Chie Watanabe, Takashi Kuwayama, Sadako Akashi-Tanaka, Seigo Nakamura, Hitoshi Zembutsu
Supplementary Figure S1.  ER status in breast cancer tissues was associated with Ki-67 response after tamoxifen therapy. (A) Ki-67 response was lower in the tissues in which the proportion of ER-positive cells was less than 2/3 than in the tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cda7d9e05983c54069e73f82173ebc
https://doi.org/10.1158/1078-0432.22465632
https://doi.org/10.1158/1078-0432.22465632
Autor:
Yusuke Nakamura, Soo Chin Lee, Ching-Wan Chan, Mikael Hartman, Ern Yu Tan, Arata Shimo, Koichiro Tsugawa, Daisuke Shimizu, Kazuhiro Shimada, Akimitsu Yamada, Shinichi Baba, Yasuaki Sagara, Ayami Matsukata, Mai Onomura, Hisamitsu Zaha, Minoru Okazaki, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Yoshie Hasegawa, Hiroshi Matsumoto, Kana Miyahara, Takashi Ishikawa, Hiroyuki Takei, Tomoko Takamaru, Chie Watanabe, Takashi Kuwayama, Sadako Akashi-Tanaka, Seigo Nakamura, Hitoshi Zembutsu
Supplementary Table S1 Association between all CYP2D6 genotype and ER status in pre-treatment tissue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbeb03daafb0aa3d97beff4ff255f1c
https://doi.org/10.1158/1078-0432.22465629
https://doi.org/10.1158/1078-0432.22465629
Autor:
Yusuke Nakamura, Soo Chin Lee, Ching-Wan Chan, Mikael Hartman, Ern Yu Tan, Arata Shimo, Koichiro Tsugawa, Daisuke Shimizu, Kazuhiro Shimada, Akimitsu Yamada, Shinichi Baba, Yasuaki Sagara, Ayami Matsukata, Mai Onomura, Hisamitsu Zaha, Minoru Okazaki, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Yoshie Hasegawa, Hiroshi Matsumoto, Kana Miyahara, Takashi Ishikawa, Hiroyuki Takei, Tomoko Takamaru, Chie Watanabe, Takashi Kuwayama, Sadako Akashi-Tanaka, Seigo Nakamura, Hitoshi Zembutsu
Purpose: CYP2D6 is the key enzyme responsible for the generation of the potent active metabolite of tamoxifen, “endoxifen.” There are still controversial reports questioning the association between CYP2D6 genotype and tamoxifen efficacy. Hence, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ce89ce8de2a1c253ff6b551d8c5a9d
https://doi.org/10.1158/1078-0432.c.6526092
https://doi.org/10.1158/1078-0432.c.6526092
Autor:
Hiroshi Onishi, Chihiro Udagawa, Michiaki Kubo, Seigo Nakamura, Sadako Akashi-Tanaka, Takashi Kuwayama, Chie Watanabe, Tomoko Takamaru, Hiroyuki Takei, Takashi Ishikawa, Kana Miyahara, Hiroshi Matsumoto, Yoshie Hasegawa, Yukihide Momozawa, Siew-Kee Low, Goro Kutomi, Hiroaki Shima, Fukino Satomi, Minoru Okazaki, Hisamitsu Zaha, Mai Onomura, Ayami Matsukata, Yasuaki Sagara, Shinichi Baba, Akimitsu Yamada, Kazuhiro Shimada, Daisuke Shimizu, Koichiro Tsugawa, Arata Shimo, Mikael Hartman, Ching-Wan Chan, Soo Chin Lee, Itaru Endo, Hitoshi Zembutsu
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201606 (2018)
PURPOSE:Although association studies of genetic variations with the clinical outcomes of breast cancer patients treated with tamoxifen have been reported, genetic factors which could determine individual response to tamoxifen are not fully clarified.
Externí odkaz:
https://doaj.org/article/df5059f5fb414b94b9b44bce028966f3
Autor:
Chihiro Udagawa, Sherwin Kuah, Tatsunori Shimoi, Ken Kato, Teruhiko Yoshida, Mari Hara Nakano, Arata Shimo, Yasuyuki Kojima, Reiko Yoshie, Koichiro Tsugawa, Taisei Mushiroda, Ern Yu Tan, Hitoshi Zembutsu
Publikováno v:
Biologicalpharmaceutical bulletin. 45(8)
Trastuzumab (herceptin) is an effective drug for human epidermal growth factor receptor type 2 (HER2)-positive cancer. However, cardiotoxicity remains a serious complication. In our previous genome-wide association study (GWAS), we identified potenti
Autor:
Arata Shimo, Ai Motoyoshi, Yoshihide Kanemaki, Hidefumi Mimura, Reiko Yoshie, Yasuyuki Kojima, Koichiro Tsugawa, Hisanori Kawamoto, Ei Haku, Akihiko Suto, Mizuho Tazo, Yukari Yabuki, Mari Hara Nakano, Mamoru Fukuda, Ichiro Maeda, Mariko Takishita, Ayaka Shimo, Ryoko Oi, Takako Kuroda, Tsuguo Iwatani, Tomoko Tsuruga
Publikováno v:
Journal of Cancer Therapy. 12:563-576
Objective: This study aimed to evaluate the feasibility, safety, and cosmetic outcomes of percutaneous cryoablation (PCA) of breast intraductal carcinoma (IDC) lesions, as well as post-cryoablation magnetic resonance imaging (MRI) as a follow-up tool
Autor:
Ei, Haku, Yasuyuki, Kojima, Kaori, Sakamaki, Mina, Kitajima, Mariko, Takishita, Nao, Sakamoto, Mizuho, Tazou, Mari, Nakano, Takako, Kuroda, Reiko, Yoshie, Tomoko, Tsuruga, Ayaka, Shimo, Arata, Shimo, Ai, Motoyoshi, Hisanori, Kawamoto, Mamoru, Fukuda, Koichiro, Tsugawa
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 47(10)
We investigated factors related to the recurrence and prognosis of patients with triple-negative breast cancer (TNBC)after neoadjuvant chemotherapy(NAC). Of the 545 patients who underwent surgery after NAC between January 2013 and December 2016, 131
Autor:
Ryosuke Hayami, Koichiro Tsugawa, Yasuyuki Kojima, Hisanori Kawamoto, Ei Haku, Kyoko Akiyama, Arata Shimo, Toru Nishikawa
Publikováno v:
Clinical Breast Cancer. 18:374-379
Background Although several studies have shown efficacy of nanoparticle albumin-bound (nab) paclitaxel use as a neoadjuvant treatment in breast cancer, dosage and schedules were varied or used in combination and the data are still limited for weekly
Autor:
Shinichi Baba, Takashi Kuwayama, Yusuke Nakamura, Hitoshi Zembutsu, Minoru Okazaki, Goro Kutomi, Fukino Satomi, Seigo Nakamura, Mikael Hartman, Kazuhiro Shimada, Sadako Akashi-Tanaka, Chie Watanabe, Tomoko Takamaru, Mai Onomura, Hiroshi Matsumoto, Arata Shimo, Kana Miyahara, Yasuaki Sagara, Hiroyuki Takei, Hiroaki Shima, Daisuke Shimizu, Soo Chin Lee, Ching Wan Chan, Hisamitsu Zaha, Akimitsu Yamada, Takashi Ishikawa, Ayami Matsukata, Yoshie Hasegawa, Ern Yu Tan, Koichiro Tsugawa
Publikováno v:
Clinical Cancer Research. 23:2019-2026
Purpose: CYP2D6 is the key enzyme responsible for the generation of the potent active metabolite of tamoxifen, “endoxifen.” There are still controversial reports questioning the association between CYP2D6 genotype and tamoxifen efficacy. Hence, w
Autor:
Hiromichi Gomi, Ai Motoyoshi, Mio Shinozaki, Yukinori Okada, Koichiro Tsugawa, Akiko Tanaka, Arata Shimo, Tatsuyuki Abe, Hisanori Kawamoto, Mariko Kobayashi, Yasuyuki Kojima, Ichiro Maeda
Publikováno v:
Journal of St. Marianna University. 8:91-101