Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Arash Y Tehrani"'
Autor:
Arash Y. Tehrani, Zoe White, Lin Wei Tung, Roy Ru Yi Zhao, Nadia Milad, Michael A. Seidman, Elodie Sauge, Marine Theret, Fabio M. V. Rossi, Mitra Esfandiarei, Casey van Breemen, Pascal Bernatchez
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract There are no therapeutics that directly enhance chronic endothelial nitric oxide (NO) release, which is typically associated with vascular homeostasis. In contrast, angiotensin II (AngII) receptor type 1 (AT1R) blockers (ARBs) can attenuate
Externí odkaz:
https://doaj.org/article/74994e0921e04e798d335b260db5ee31
Autor:
Arash Y. Tehrani, Zoe White, Nadia Milad, Mitra Esfandiarei, Michael A. Seidman, Pascal Bernatchez
Publikováno v:
Physiological Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)
Abstract Marfan syndrome (MFS) is a genetic disorder that results in accelerated aortic root widening and aneurysm. However, management of MFS patients with blood pressure (BP)‐lowering medications, such as angiotensin II (AngII) receptor blocker (
Externí odkaz:
https://doaj.org/article/e479c412085d46fe8795042de6d00b01
Publikováno v:
Nitric Oxide. 131:18-25
Low basal nitric oxide (NO) production is associated with a dysfunctional endothelium and vascular diseases. We have shown that some angiotensin II (AngII) receptor type 1 (AT1R) blockers (ARBs), a group of clinic-approved blood pressure (BP)-lowerin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33708a59fda3822bf4390a3a0394925b
https://doi.org/10.1016/j.niox.2022.12.002
https://doi.org/10.1016/j.niox.2022.12.002
Autor:
Nadia Milad, Zoe White, Arash Y. Tehrani, Stephanie Sellers, Fabio M.V. Rossi, Pascal Bernatchez
Publikováno v:
Skeletal Muscle, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Background Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin expression and leads to severe ambulatory and cardiac function decline. However, the dystrophin-deficient mdx murine model of DMD only develops a very mild form of
Externí odkaz:
https://doaj.org/article/4082bb3c366a4c5d9e48341a1ab378f2
Autor:
Zoe White, Nadia Milad, Arash Y Tehrani, William Wei-Han Chen, Graham Donen, Stephanie L Sellers, Pascal Bernatchez
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220903 (2019)
There is no cure or beneficial management option for Limb-Girdle muscular dystrophy (MD) type 2B (LGMD2B). Losartan, a blood pressure (BP) lowering angiotensin II (AngII) receptor type 1 (ATR1) blocker (ARB) with unique anti-transforming growth facto
Externí odkaz:
https://doaj.org/article/be524c11a5c04573acfffd11c054bb2a
Autor:
Elodie Sauge, Dmitri Pechkovsky, N.D. Prasad Atmuri, Arash Y. Tehrani, Zoe White, Ying Dong, Jessica Cait, Michael Hughes, Anthony Tam, Graham Donen, Christopher Yuen, Michael J.A. Walker, Kelly M. McNagny, Don D. Sin, Marco A. Ciufolini, Pascal Bernatchez
Publikováno v:
Vascular pharmacology. 147
Losartan is an anti-hypertensive angiotensin II (ANGII) type 1 receptor (AT1R) blocker (ARB) with many unexpected therapeutic properties, even in non-blood pressure (BP)-related diseases. Administered as a prodrug, losartan undergoes serial metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a2d6344d86c2b80063c7d3b67b3bbd
https://pubmed.ncbi.nlm.nih.gov/36179789
https://pubmed.ncbi.nlm.nih.gov/36179789
Publikováno v:
Nitric oxide : biology and chemistry. 116
Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1 gene, which encodes fibrillin-1, a protein essential for the formation and stabilization of elastic fibers as well as signaling homeostasis. Progressive aortic root
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a8e8c1ecefe62e5b22c08005861ced
https://pubmed.ncbi.nlm.nih.gov/34478846
https://pubmed.ncbi.nlm.nih.gov/34478846
Autor:
Pascal Bernatchez, Mitra Esfandiarei, Michael A. Seidman, Nadia Milad, Zoe White, Arash Y. Tehrani
Publikováno v:
Physiological Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)
Physiological Reports
Physiological Reports
Marfan syndrome (MFS) is a genetic disorder that results in accelerated aortic root widening and aneurysm. However, management of MFS patients with blood pressure (BP)‐lowering medications, such as angiotensin II (AngII) receptor blocker (ARB) losa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abee53b5f9de3d07e9f8485c539e452a
https://doaj.org/article/e479c412085d46fe8795042de6d00b01
https://doaj.org/article/e479c412085d46fe8795042de6d00b01
Autor:
Mitra Esfandiarei, Nicola Fameli, Yohan Y H Choi, Arash Y Tehrani, Jeremy G Hoskins, Cornelis van Breemen
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55333 (2013)
Agonist-stimulated smooth muscle Ca2+ waves regulate blood vessel tone and vasomotion. Previous studies employing cytoplasmic Ca2+ indicators revealed that these Ca2+ waves were stimulated by a combination of inositol 1,4,5-trisphosphate- and Ca2+ -i
Externí odkaz:
https://doaj.org/article/69fc7139b44d4c66929211ef7c553a42
Autor:
Monica Castro, Cornelis van Breemen, Arash Y. Tehrani, Mitra Esfandiarei, Pascal Bernatchez, Ester Hotova, T. Bucky Jones, Jason Z. Cui
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Marfan syndrome (MFS) is a connective tissue disorder that results in aortic root widening and aneurysm if unmanaged. We have previously reported doxycycline, a nonselective matrix metalloproteinases (MMPs) inhibitor, to attenuate aortic root widenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d312c43c2d8278859cb5f0aed7d9bb55
https://doi.org/10.1038/s41598-020-64071-8
https://doi.org/10.1038/s41598-020-64071-8