Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Arash, Rafii"'
Autor:
Alejandra Martinez, Gwenael Ferron, Fabrice Lécuru, Patrice Mathevet, Maha Ayyoub, Anne-Sophie Navarro, Arash Rafii, Anna Salvioni, Marie Michelas, Gaurav Thareja, Françoise Lauzeral-Vizcaino, Najeeb Halabi, Eliane Mery-Lamarche, Noemie Thebault, Clara-Maria Scarlata, Jonathan Khalifa
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Cervical cancer’s lymphatic spread primarily begins from the sentinel lymph nodes (SLNs), underlining their pivotal role in disease metastasis. However, these nodes’ immune gene expression profiles and immunoregulation mechanisms have
Externí odkaz:
https://doaj.org/article/8be0f11ddce545bb8838776ab4c78f1f
Autor:
Halema Al-Farsi, Iman Al-Azwani, Joel A. Malek, Lotfi Chouchane, Arash Rafii, Najeeb M. Halabi
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Mutated and non-mutated genes interact to drive cancer growth and metastasis. While research has focused on understanding the impact of mutated genes on cancer biology, understanding non-mutated genes that are essential to tumor d
Externí odkaz:
https://doaj.org/article/cef8992aa6344a3d8dbeb94ea4a73873
Autor:
Isra Marei, Omar Chidiac, Binitha Thomas, Jennifer Pasquier, Soha Dargham, Amal Robay, Muneera Vakayil, Mohammad Jameesh, Christopher Triggle, Arash Rafii, Amin Jayyousi, Jassim Al Suwaidi, Charbel Abi Khalil
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-17 (2022)
Abstract Background Elevated endothelial microparticles (EMPs) levels are surrogate markers of vascular dysfunction. We analyzed EMPs with apoptotic characteristics and assessed the angiogenic contents of microparticles in the blood of patients with
Externí odkaz:
https://doaj.org/article/d9f1b24459934fd4943b7174e6aff4d6
Autor:
Yasser Majeed, Najeeb Halabi, Aisha Y. Madani, Rudolf Engelke, Aditya M. Bhagwat, Houari Abdesselem, Maha V. Agha, Muneera Vakayil, Raphael Courjaret, Neha Goswami, Hisham Ben Hamidane, Mohamed A. Elrayess, Arash Rafii, Johannes Graumann, Frank Schmidt, Nayef A. Mazloum
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract The NAD+-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD+ boosters alleviate metabolic complications. We previously
Externí odkaz:
https://doaj.org/article/089c9cec17554b53999e1600d089c034
Autor:
Arthur Jacob, Jennifer Pasquier, Raphael Carapito, Frédéric Auradé, Anne Molitor, Philippe Froguel, Khalid Fakhro, Najeeb Halabi, Géraldine Viot, Seiamak Bahram, Arash Rafii
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Mandibulofacial dysostosis with microcephaly (MFDM) is a rare autosomal dominant genetic disease characterized by intellectual and growth retardations, as well as major microcephaly, induced by missense and splice site variants or
Externí odkaz:
https://doaj.org/article/d9d64217f70444de95fa1d71d02b591e
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract The concept of cancer as a cell-autonomous disease has been challenged by the wealth of knowledge gathered in the past decades on the importance of tumor microenvironment (TM) in cancer progression and metastasis. The significance of endothe
Externí odkaz:
https://doaj.org/article/74965d177f86438a8ecda1f4140663ba
Autor:
Jessica Hoarau-Véchot, Morgane Blot-Dupin, Léa Pauly, Cyril Touboul, Shahin Rafii, Arash Rafii, Jennifer Pasquier
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14173 (2022)
Ovarian cancer (OC) is a heterogeneous disease characterized by its late diagnosis (FIGO stages III and IV) and the importance of abdominal metastases often observed at diagnosis. Detached ovarian cancer cells (OCCs) float in ascites and form multice
Externí odkaz:
https://doaj.org/article/71639385de13405baeb3598dbf23ede8
Autor:
Thasni Karedath, Ikhlak Ahmed, Wafa Al Ameri, Fatima M. Al-Dasim, Simeon S. Andrews, Samson Samuel, Iman K. Al-Azwani, Yasmin Ali Mohamoud, Arash Rafii, Joel A. Malek
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-17 (2019)
Abstract Background Circular RNAs (circRNAs) that form through non-canonical backsplicing events of pre-mRNA transcripts are evolutionarily conserved and abundantly expressed across species. However, the functional relevance of circRNAs remains a top
Externí odkaz:
https://doaj.org/article/49ecec08064b48a4854176c6123b5d34
Autor:
Jessica Hoarau-Véchot, Cyril Touboul, Najeeb Halabi, Morgane Blot-Dupin, Raphael Lis, Charbel Abi Khalil, Shahin Rafii, Arash Rafii, Jennifer Pasquier
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background One main challenge in ovarian cancer rests on the presence of a relapse and an important metastatic disease, despite extensive surgical debulking and chemotherapy. The difficulty in containing metastatic cancer is partly due to th
Externí odkaz:
https://doaj.org/article/3d56a8a004d8412d8cab9f1d63d6cf73
Autor:
Lotfi Chouchane, Jean-Charles Grivel, Elmoubasher Abu Baker Abd Farag, Igor Pavlovski, Selma Maacha, Abbirami Sathappan, Hamad Eid Al-Romaihi, Sirin W.J. Abuaqel, Manar Mahmoud Ahmad Ata, Aouatef Ismail Chouchane, Sami Remadi, Najeeb Halabi, Arash Rafii, Mohammed H. Al-Thani, Nico Marr, Murugan Subramanian, Jingxuan Shan
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
The development of prophylactic and therapeutic agents for coronavirus disease 2019 (COVID-19) is a current global health priority. Here, we investigated the presence of cross-neutralizing antibodies against severe acute respiratory syndrome coronavi
Externí odkaz:
https://doaj.org/article/78735e02d86248bba861c7d04c9abd1f