Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Aras N. Mattis"'
Autor:
Sami T. Tuomivaara, Susan J. Fisher, Steven C. Hall, Dana E. Goin, Aras N. Mattis, Pamela K. Den Besten
Publikováno v:
Environmental Health, Vol 23, Iss 1, Pp 1-6 (2024)
Abstract Background Fluoride exposure during pregnancy has been associated with various effects on offspring, including changes in behavior and IQ. To provide clues to possible mechanisms by which fluoride may affect human fetal development, we compl
Externí odkaz:
https://doaj.org/article/056631136b1d45bba2b8d87240cd6b0f
Autor:
Mahbubul H. Shihan, Sachin Sharma, Carson Cable, Vijaya Prathigudupu, Alina Chen, Aras N. Mattis, Jennifer Y. Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Hepatic fibrosis is driven by the activation of hepatic stellate cells (HSCs). The Hippo pathway and its effectors, YAP and TAZ, are key regulators of HSC activation and fibrosis. However, there is a lack of mechanistic understanding of YAP/
Externí odkaz:
https://doaj.org/article/da53c32d081d422e9d8ac3a11c1158ca
Autor:
Noura Tbeileh, Luika Timmerman, Aras N. Mattis, Kan Toriguchi, Yosuke Kasai, Carlos Corvera, Eric Nakakura, Kenzo Hirose, David B. Donner, Robert S. Warren, Eveliina Karelehto
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Tumors rich in stroma are associated with advanced stage and poor prognosis in colorectal adenocarcinoma (CRC). Abundance of stromal cells also has implications for genomic analysis of patient tumors as it may prevent detection of somatic mutations.
Externí odkaz:
https://doaj.org/article/698296ae8d574774a73563684992df82
Autor:
Amy Yu, Carson Cable, Sachin Sharma, Mahbubul H. Shihan, Aras N. Mattis, Izolda Mileva, Yusuf A. Hannun, Caroline C. Duwaerts, Jennifer Y. Chen
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Non-alcoholic fatty liver disease (NAFLD) is a common cause of liver disease worldwide, and is characterized by the accumulation of fat in the liver. Non-alcoholic steatohepatitis (NASH), an advanced form of NAFLD, is a leading cause of liver transpl
Externí odkaz:
https://doaj.org/article/6725eb13e1904aa59cea259f043342fe
Autor:
Yanina Bogliotti, Mark Vander Roest, Aras N. Mattis, Robert G. Gish, Gary Peltz, Robin Anwyl, Salah Kivlighn, Eric R. Schuur
Publikováno v:
Cells, Vol 11, Iss 13, p 1998 (2022)
Liver disease is a leading cause of mortality worldwide, resulting in 1.3 million deaths annually. The vast majority of liver disease is caused by metabolic disease (i.e., NASH) and alcohol-induced hepatitis, and to a lesser extent by acute and chron
Externí odkaz:
https://doaj.org/article/c91ee481ad5a4ef09fbe50118203adfa
Autor:
Yu-Lin Kuang, Antonio Munoz, Gilbert Nalula, Katherine E. Santostefano, Valentina Sanghez, Gabriela Sanchez, Naohiro Terada, Aras N. Mattis, Michelina Iacovino, Carlos Iribarren, Ronald M. Krauss, Marisa W. Medina
Publikováno v:
Stem Cell Research, Vol 37, Iss , Pp - (2019)
Patient-derived induced pluripotent stem cells (iPSCs) have become a promising resource for exploring genetics of complex diseases, discovering new drugs, and advancing regenerative medicine. Increasingly, laboratories are creating their own banks of
Externí odkaz:
https://doaj.org/article/7c15eabdc9724fd391a8a8b8139bc304
Autor:
Julia Sbierski-Kind, Kelly M Cautivo, Johanna C Wagner, Madelene W Dahlgren, Julia Nilsson, Maria Krasilnikov, Nicholas M. Mroz, Carlos O. Lizama, Anna Lu Gan, Peri R Matatia, Marcela T Taruselli, Anthony A Chang, Sofia Caryotakis, Claire E O’Leary, Maya Kotas, Aras N Mattis, Tien Peng, Richard M Locksley, Ari B Molofsky
Publikováno v:
bioRxiv
SUMMARYGroup 2 innate lymphoid cells (ILC2s) cooperate with adaptive Th2 cells as key organizers of tissue type 2 immune responses, while a spectrum of innate and adaptive lymphocytes coordinate early type 3/17 immunity. Both type 2 and type 3/17 lym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b1d9bc72372610e190cfc73ab88ec8
https://doi.org/10.1101/2023.04.26.537913
https://doi.org/10.1101/2023.04.26.537913
Publikováno v:
Histopathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fdcdc02512e516f97f3c4e4fdec86ae
https://doi.org/10.1111/his.14913
https://doi.org/10.1111/his.14913
Publikováno v:
Stem cells (Dayton, Ohio), vol 41, iss 2
Human induced pluripotent stem cell (iPSC)-derived liver organoids serve as models of organogenesis, disease, drug screening, and regenerative medicine. Prevailing methods for generating organoids rely on Matrigel, whose batch-to-batch variability an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2e7afb3de3b6a21f433c78603a2437
https://escholarship.org/uc/item/7r84892g
https://escholarship.org/uc/item/7r84892g
Autor:
Jacquelyn J. Maher, Aras N. Mattis, Ke Liu, Tao Su, Caitlin Peaslee, Sneha Rao, Cristina Esteva-Font, Julie B. Sneddon, Antonio Munoz-Howell, Zhe Liu, Caroline C. Duwaerts, Marisa W. Medina
Publikováno v:
Hepatology (Baltimore, Md.), vol 74, iss 4
Hepatology
Hepatology
BACKGROUND AND AIMS: Induced pluripotent stem cells (iPSCs) provide an important tool for the generation of patient-derived cells, including hepatocyte-like cells, by developmental cues through an endoderm intermediate. However, most iPSC lines fail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8c79d28bb12399013bb1f0885790dc
https://doi.org/10.1002/hep.31898
https://doi.org/10.1002/hep.31898