Výsledky vyhledávání - "Aranyak, Goswami"

Akademický článek

Drinking and smoking polygenic risk is associated with childhood and early-adulthood psychiatric and behavioral traits independently of substance use and psychiatric genetic risk

Autor: Flavio De Angelis, Frank R. Wendt, Gita A. Pathak, Daniel S. Tylee, Aranyak Goswami, Joel Gelernter, Renato Polimanti

Publikováno v: Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)

Abstract Alcohol drinking and tobacco smoking are hazardous behaviors associated with a wide range of adverse health outcomes. In this study, we explored the association of polygenic risk scores (PRS) related to drinks per week, age of smoking initia

Externí odkaz: https://doaj.org/article/0c33d29b495346df95b44cbea68f5ccb

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Akademický článek

ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 Susceptibility

Autor: Gita A. Pathak, Frank R. Wendt, Aranyak Goswami, Dora Koller, Flavio De Angelis, COVID-19 Host Genetics Initiative, Renato Polimanti

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

Angiotensin-converting enzyme-2 (ACE2) receptor has been identified as the key adhesion molecule for the transmission of the SARS-CoV-2. However, there is no evidence that human genetic variation in ACE2 is singularly responsible for COVID-19 suscept

Externí odkaz: https://doaj.org/article/3714f837f8fb431da148372d66487892

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Akademický článek

Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality

Autor: Frank R. Wendt, Gita A. Pathak, Daniel F. Levey, Yaira Z. Nuñez, Cassie Overstreet, Chelsea Tyrrell, Keyrun Adhikari, Flavio De Angelis, Daniel S. Tylee, Aranyak Goswami, John H. Krystal, Chadi G. Abdallah, Murray B. Stein, Henry R. Kranzler, Joel Gelernter, Renato Polimanti

Publikováno v: Neurobiology of Stress, Vol 14, Iss , Pp 100309- (2021)

Epidemiologic studies recognize that trauma and posttraumatic stress are associated with heightened suicidal behavior severity, yet examination of these associations from a genetic perspective is limited. We performed a multivariate gene-by-environme

Externí odkaz: https://doaj.org/article/f4314c06b5c842d5a0bea71d1092ebcf

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Akademický článek

Heterogeneity and Polygenicity in Psychiatric Disorders: A Genome-Wide Perspective

Autor: Frank R. Wendt, Gita A. Pathak, Daniel S. Tylee, Aranyak Goswami, Renato Polimanti

Publikováno v: Chronic Stress, Vol 4 (2020)

Genome-wide association studies (GWAS) have been performed for many psychiatric disorders and revealed a complex polygenic architecture linking mental and physical health phenotypes. Psychiatric diagnoses are often heterogeneous, and several layers o

Externí odkaz: https://doaj.org/article/dc624197af7c40deb3af4ce8bdab4fb6

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SURPAS Long Range Planning Report 2023

Autor: Eamon Byrne, Tim MG MacKenzie, aranyak goswami, Samyuktha Suresh, M. Usman Ahmad

Since early 2020, the Stanford University Postdoc Association, known as SURPAS, has been building a community-oriented vision for the future of postdocs at Stanford. This effort sought to answer the question: “What do postdocs think about the postd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bbcfbafa0870075afcda98fd81ae735
https://doi.org/10.31219/osf.io/t5mwn

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ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 Susceptibility

Autor: Flavio De Angelis, Frank R. Wendt, Renato Polimanti, Aranyak Goswami, Dora Koller, Gita A. Pathak, Covid Host Genetics Initiative

Publikováno v: Frontiers in Genetics
Frontiers in genetics, 12:698033. Frontiers Media S.A.
Frontiers in Genetics, Vol 12 (2021)
medRxiv
article-version (status) pre
article-version (number) 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5a27c4695d5a390f09b43d4c1e5760

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Drinking and smoking polygenic risk is associated with childhood and early-adulthood psychiatric and behavioral traits independently of substance use and psychiatric genetic risk

Autor: Daniel S. Tylee, Gita A. Pathak, Renato Polimanti, Frank R. Wendt, Aranyak Goswami, Flavio De Angelis, Joel Gelernter

Publikováno v: Translational Psychiatry
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)

Alcohol drinking and tobacco smoking are hazardous behaviors associated with a wide range of adverse health outcomes. In this study, we explored the association of polygenic risk scores (PRS) related to drinks per week, age of smoking initiation, smo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6653435bf34ffed8b97a1ede0f7ff8e
https://pubmed.ncbi.nlm.nih.gov/34775470

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Epigenomic Profiles of African-American Transthyretin Val122Ile Carriers Reveals Putatively Dysregulated Amyloid Mechanisms

Autor: Frank R. Wendt, Flavio De Angelis, Antonella De Lillo, Joel Gelernter, Aranyak Goswami, Henry R. Kranzler, Yaira Z. Nunez, Maria Fuciarelli, Gita A. Pathak, Renato Polimanti

Publikováno v: Circulation: Genomic and Precision Medicine. 14

Background: The Val122Ile mutation in Transthyretin ( TTR ) gene causes a rare, difficult to diagnose hereditary form of cardiac amyloidosis. This mutation is most common in the United States and mainly present in people of African descent. The carri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7a3b57fe77fa8514b9f88bffc6c9212
https://doi.org/10.1161/circgen.120.003011

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Epigenomic Profiles of African-American

Autor: Gita A, Pathak, Frank R, Wendt, Antonella, De Lillo, Yaira Z, Nunez, Aranyak, Goswami, Flavio, De Angelis, Maria, Fuciarelli, Henry R, Kranzler, Joel, Gelernter, Renato, Polimanti

Publikováno v: Circ Genom Precis Med

BACKGROUND -: The Val122Ile mutation in Transthyretin (TTR) gene causes a rare, difficult to diagnose hereditary form of cardiac amyloidosis. This mutation is most common in the United States and mainly present in people of African descent. The carri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3c4b812b1cc60046bb51e7b8253debbb
https://pubmed.ncbi.nlm.nih.gov/33428857

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ACE2 Netlas: In-silico functional characterization and drug-gene interactions of ACE2 gene network to understand its potential involvement in COVID-19 susceptibility

Autor: Gita A. Pathak, Flavio De Angelis, Frank R. Wendt, Aranyak Goswami, Renato Polimanti

Publikováno v: medRxiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a05ce51ee5771bacfe0a55c7fabaaf8
https://doi.org/10.1101/2020.10.27.20220665

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