Subsequent pregnancies in peripartum cardiomyopathy: Patient-level differences and decision-making.

Autor: Irizarry OC; Department of Obstetrics & Gynecology, St. Luke's University Health Network, Bethlehem, PA, United States of America., Lewey J; Division of Cardiovascular Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America., McCallister C; Division of Gynecology Oncology, Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine., Koelper NC; Center for Research on Reproduction and Patient's Health, Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America., Arany Z; Division of Cardiovascular Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America., Levine LD; Pregnancy and Perinatal Research Center, Department of Obstetrics and Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America.

Publikováno v: American heart journal plus : cardiology research and practice [Am Heart J Plus] 2024 Oct 11; Vol. 47, pp. 100472. Date of Electronic Publication: 2024 Oct 11 (Print Publication: 2024).

SGLT2 Inhibitors Act Independently of SGLT2 to Confer Benefit for HFrEF in Mice.

Autor: Berger JH; Division of Cardiology, Cardiovascular Institute, Children's Hospital of Philadelphia, Philadelphia, PA (J.H.B., D.P.K.).; Department of Medicine, Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.H.B., T.R.M., C.E.B., R.T., J.P., L.L., T.C.L., Z.A., D.P.K.)., Matsuura TR; Department of Medicine, Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.H.B., T.R.M., C.E.B., R.T., J.P., L.L., T.C.L., Z.A., D.P.K.)., Bowman CE; Department of Medicine, Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.H.B., T.R.M., C.E.B., R.T., J.P., L.L., T.C.L., Z.A., D.P.K.).; Department of Biology, Williams College, Williamstown, MA (C.E.B.)., Taing R; Department of Medicine, Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.H.B., T.R.M., C.E.B., R.T., J.P., L.L., T.C.L., Z.A., D.P.K.)., Patel J; Department of Medicine, Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.H.B., T.R.M., C.E.B., R.T., J.P., L.L., T.C.L., Z.A., D.P.K.)., Lai L; Department of Medicine, Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.H.B., T.R.M., C.E.B., R.T., J.P., L.L., T.C.L., Z.A., D.P.K.)., Leone TC; Department of Medicine, Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.H.B., T.R.M., C.E.B., R.T., J.P., L.L., T.C.L., Z.A., D.P.K.)., Reagan JD; Amgen Research, Cardiometabolic Disorders, South San Francisco, CA (J.D.R., S.M.H.)., Haldar SM; Amgen Research, Cardiometabolic Disorders, South San Francisco, CA (J.D.R., S.M.H.)., Arany Z; Department of Medicine, Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.H.B., T.R.M., C.E.B., R.T., J.P., L.L., T.C.L., Z.A., D.P.K.)., Kelly DP; Division of Cardiology, Cardiovascular Institute, Children's Hospital of Philadelphia, Philadelphia, PA (J.H.B., D.P.K.).; Department of Medicine, Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.H.B., T.R.M., C.E.B., R.T., J.P., L.L., T.C.L., Z.A., D.P.K.).

Publikováno v: Circulation research [Circ Res] 2024 Aug 16; Vol. 135 (5), pp. 632-634. Date of Electronic Publication: 2024 Jul 23.

SGLT2 inhibitors activate pantothenate kinase in the human heart.

Autor: Forelli N; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Eaton D; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Patel J; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Bowman CE; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Kawakami R; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Kuznetsov IA; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Li K; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Brady C; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Bedi K; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Yang Y; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Koya K; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Megill E; Aging & Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Kanter DS; Aging & Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Smith LG; Departments of Biochemistry & Biophysics, and Bioengineering, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Bowman GR; Departments of Biochemistry & Biophysics, and Bioengineering, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Snyder N; Aging & Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Edwards J; Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA., Margulies K; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Arany Z; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 27. Date of Electronic Publication: 2024 Jul 27.

Partial suppression of BCAA catabolism as a potential therapy for BCKDK deficiency.

Autor: Ohl L; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.; College of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA., Kuhs A; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Pluck R; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Durham E; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Noji M; College of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Philip ND; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Arany Z; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Ahrens-Nicklas RC; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

Publikováno v: Molecular genetics and metabolism reports [Mol Genet Metab Rep] 2024 May 10; Vol. 39, pp. 101091. Date of Electronic Publication: 2024 May 10 (Print Publication: 2024).

Sodium-glucose co-transporter 2 Inhibitors Act Independently of SGLT2 to Confer Benefit for Heart Failure with Reduced Ejection Fraction in Mice.

Autor: Berger JH, Matsuura TR, Bowman CE, Taing R, Patel J, Lai L, Leone TC, Reagan JD, Haldar SM, Arany Z, Kelly DP

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 02. Date of Electronic Publication: 2024 May 02.