Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Arantza Sanz-Parra"'
Autor:
Sofia Lachiondo-Ortega, Claudia M. Rejano-Gordillo, Jorge Simon, Fernando Lopitz-Otsoa, Teresa C. Delgado, Krystyna Mazan-Mamczarz, Naroa Goikoetxea-Usandizaga, L. Estefanía Zapata-Pavas, Ana García-del Río, Pietro Guerra, Patricia Peña-Sanfélix, Natalia Hermán-Sánchez, Ruba Al-Abdulla, Carmen Fernandez-Rodríguez, Mikel Azkargorta, Alejandro Velázquez-Cruz, Joris Guyon, César Martín, Juan Diego Zalamea, Leire Egia-Mendikute, Arantza Sanz-Parra, Marina Serrano-Maciá, Irene González-Recio, Monika Gonzalez-Lopez, Luis Alfonso Martínez-Cruz, Patrizia Pontisso, Ana M. Aransay, Rosa Barrio, James D. Sutherland, Nicola G.A. Abrescia, Félix Elortza, Amaia Lujambio, Jesus M. Banales, Raúl M. Luque, Manuel D. Gahete, Asís Palazón, Matias A. Avila, Jose J. G. Marin, Supriyo De, Thomas Daubon, Antonio Díaz-Quintana, Irene Díaz-Moreno, Myriam Gorospe, Manuel S. Rodríguez, María Luz Martínez-Chantar
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113924- (2024)
Summary: The posttranslational modification of proteins critically influences many biological processes and is a key mechanism that regulates the function of the RNA-binding protein Hu antigen R (HuR), a hub in liver cancer. Here, we show that HuR is
Externí odkaz:
https://doaj.org/article/ac05448b67bf43d08eefd6737eb5e995
Autor:
Chiara Bruzzone, Rubén Gil-Redondo, Marisa Seco, Rocío Barragán, Laura de la Cruz, Claire Cannet, Hartmut Schäfer, Fang Fang, Tammo Diercks, Maider Bizkarguenaga, Beatriz González-Valle, Ana Laín, Arantza Sanz-Parra, Oscar Coltell, Ander López de Letona, Manfred Spraul, Shelly C. Lu, Elisabetta Buguianesi, Nieves Embade, Quentin M. Anstee, Dolores Corella, José M. Mato, Oscar Millet
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract Background Metabolic syndrome (MetS) is a multimorbid long-term condition without consensual medical definition and a diagnostic based on compatible symptomatology. Here we have investigated the molecular signature of MetS in urine. Methods
Externí odkaz:
https://doaj.org/article/fdd2825fb92b43c38b52b9294746026e
Autor:
Jon Gil-Martínez, Iratxe Macias, Luca Unione, Ganeko Bernardo-Seisdedos, Fernando Lopitz-Otsoa, David Fernandez-Ramos, Ana Lain, Arantza Sanz-Parra, José M Mato, Oscar Millet
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1789 (2021)
Fumarylacetoacetate hydrolase (FAH) is the fifth enzyme in the tyrosine catabolism pathway. A deficiency in human FAH leads to hereditary tyrosinemia type I (HT1), an autosomal recessive disorder that results in the accumulation of toxic metabolites
Externí odkaz:
https://doaj.org/article/e4a3a0a3ffdb44afb1f8afaae175f6de
Autor:
Sofia Lachiondo-Ortega, Miren Bravo, Irene González-Recio, María J. González Rellán, Jorge Simón Espinosa, Naroa Goikoetxea, Petar Petrov, Rubén Rodríguez Agudo, Arantza Sanz-Parra, Begoña Rodriguez Iruretagoyena, Teresa Cardoso Delgado, Dan A. Dixon, Myriam Gorospe, Ruben Nogueiras, María Luz Martínez-Chantar
Publikováno v:
Journal of Hepatology. 77:S84-S85
Autor:
Antonio Fontanellas, Rafael Enríquez de Salamanca, Arantza Sanz-Parra, Oscar Millet, Ana Sampedro, Naroa Serna, Fernando J. Corrales, Pedro Berraondo, Irantzu Serrano-Mendioroz
Publikováno v:
Human Molecular Genetics. 27:3688-3696
A first-in-human gene therapy trial using a recombinant adeno-associated viral (rAAV) vector for acute intermittent porphyria (AIP) reveals that higher doses would be required to reach therapeutic levels of the porphobilinogen deaminase (PBGD) transg
Autor:
Chiara Bruzzone, Rubén Gil-Redondo, Laura delaCruz-Villar, Arantza Sanz-Parra, Dolores Corella, Nieves Embade, José M. Mato, Oscar Millet
Publikováno v:
Journal of Hepatology. 73:S288-S289
Autor:
Joaquín Castilla, Pedro Urquiza, Jean-Marc Blouin, Fredj Ben Bdira, Virginia Gutiérrez-de-Juan, Iratxe Macías, Oscar Millet, Ana Laín, Arantza Sanz-Parra, Juan Anguita, José M. Mato, Ganeko Bernardo-Seisdedos, Gabriel Ortega, Jorge Moreno, Juan M. Falcón-Pérez, Julen Oyarzabal, Itxaso San Juan, Juan Rodríguez-Cuesta, Emmanuel Richard, Emilio Díez, Sandra García, Paula Pluta, Rosario González-Muñiz, Pierre Dubus, Hubert de Verneuil, Hasier Eraña, Esperanza Gonzalez
Publikováno v:
Science Translational Medicine. 10
Congenital erythropoietic porphyria is a rare autosomal recessive disease produced by deficient activity of uroporphyrinogen III synthase, the fourth enzyme in the heme biosynthetic pathway. The disease impacts many organs, can be life-threatening an
Autor:
José M. Mato, Ganeko Bernardo-Seisdedos, Oscar Millet, Luca Unione, Jon Gil-Martínez, Arantza Sanz-Parra, David Fernández-Ramos, Iratxe Macías, Ana Laín, Fernando Lopitz-Otsoa
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1789, p 1789 (2021)
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1789, p 1789 (2021)
Fumarylacetoacetate hydrolase (FAH) is the fifth enzyme in the tyrosine catabolism pathway. A deficiency in human FAH leads to hereditary tyrosinemia type I (HT1), an autosomal recessive disorder that results in the accumulation of toxic metabolites
Autor:
Cécile Ged, Ganeko Bernardo-Seisdedos, Pedro Urquiza, Emmanuel Richard, Arantza Sanz-Parra, Jean-Marc Blouin, Magalie Lalanne, Julie Esteve, Hubert de Verneuil, Oscar Millet, Emma Sasso
Publikováno v:
Human molecular genetics. 26(8)
Congenital erythropoietic porphyria (CEP) is an inborn error of heme biosynthesis characterized by uroporphyrinogen III synthase (UROS) deficiency resulting in deleterious porphyrin accumulation in blood cells responsible for hemolytic anemia and cut
Autor:
David Gubb, Arantza Sanz-Parra, Ane Fullaondo, Susana García-Sánchez, Emma Recio, So Young Lee
Publikováno v:
Molecular and Cellular Biology. 31:2960-2972
The Drosophila genome encodes 29 serpins, most of unknown function. We show here that Spn1 is an active protease inhibitor of the serpin superfamily. Spn1 inhibits trypsin in vitro and regulates the Toll-mediated immune response in vivo. Expression o