Probing the operability regime of an engineered ribocomputing unit in terms of dynamic range maintenance with extracellular changes and time

Autor: Roser Montagud-Martínez, Jordi Ventura, Rafael Ballesteros-Garrido, Arantxa Rosado, Guillermo Rodrigo

Publikováno v: Journal of Biological Engineering, Vol 14, Iss 1, Pp 1-12 (2020)

Abstract Synthetic biology aims at engineering gene regulatory circuits to end with cells (re)programmed on purpose to implement novel functions or discover natural behaviors. However, one overlooked question is whether the resulting circuits perform

Externí odkaz: https://doaj.org/article/794f719eff734527b7cc4bf89e132fd1

Probing the operability regime of an engineered ribocomputing unit in terms of dynamic range maintenance with extracellular changes and time

Autor: Arantxa Rosado, Rafael Ballesteros-Garrido, Jordi Ventura, Guillermo Rodrigo, Roser Montagud-Martínez

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Biological Engineering
Journal of Biological Engineering, Vol 14, Iss 1, Pp 1-12 (2020)

Synthetic biology aims at engineering gene regulatory circuits to end with cells (re)programmed on purpose to implement novel functions or discover natural behaviors. However, one overlooked question is whether the resulting circuits perform as inten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8871b4f39e572961aa2ccaf25890126
http://hdl.handle.net/10261/206314

Binary addition in a living cell based on riboregulation

Autor: Guillermo Rodrigo, Arantxa Rosado, Teresa Cordero

Publikováno v: PLoS Genetics
PLoS Genetics, Vol 14, Iss 7, p e1007548 (2018)

Synthetic biology aims at (re-)programming living cells like computers to perform new functions for a variety of applications. Initial work rested on transcription factors, but regulatory RNAs have recently gained much attention due to their high pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4491fdf60c7f51abaf9c9a784544352
http://europepmc.org/articles/PMC6067762

Exploring cellular senescence as a tumor suppressor mechanism

Autor: Arantxa Rosado, Amancio Carnero, Victoria Moneo, Carmen Blanco, Oliver Renner, Maria V. Guijarro, Maria E. Castro, Fernando Blanco, Wolfgang Link, Lourdes Romero, Jesús Fominaya, Juan F. Martínez

Publikováno v: Scopus-Elsevier
CIÊNCIAVITAE

Somatic cells show a spontaneous decline in growth rate on continuous culture, related not to elapsed time but to an increasing number of population doublings, eventually terminating in a quiescent but viable state, termed replicative senescence. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6c1c6a847fa05faa397e86dbf8d81f
http://www.scopus.com/inward/record.url?eid=2-s2.0-33646253025&partnerID=MN8TOARS