Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Arantxa Gutierrez"'
Autor:
Glòria Mas, Fabio Santoro, Enrique Blanco, Gianni Paolo Gamarra Figueroa, François Le Dily, Gianmaria Frigè, Enrique Vidal, Francesca Mugianesi, Cecilia Ballaré, Arantxa Gutierrez, Aleksandra Sparavier, Marc A. Marti-Renom, Saverio Minucci, Luciano Di Croce
Publikováno v:
Genes & Dev
Genome organization plays a pivotal role in transcription, but how transcription factors (TFs) rewire the structure of the genome to initiate and maintain the programs that lead to oncogenic transformation remains poorly understood. Acute promyelocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3103e2f22d1ac61ebb6216e89023f71d
http://hdl.handle.net/10230/53063
http://hdl.handle.net/10230/53063
Autor:
Glòria, Mas, Fabio, Santoro, Enrique, Blanco, Gianni Paolo, Gamarra Figueroa, François, Le Dily, Gianmaria, Frigè, Enrique, Vidal, Francesca, Mugianesi, Cecilia, Ballaré, Arantxa, Gutierrez, Aleksandra, Sparavier, Marc A, Marti-Renom, Saverio, Minucci, Luciano, Di Croce
Publikováno v:
Genesdevelopment. 36(7-8)
Genome organization plays a pivotal role in transcription, but how transcription factors (TFs) rewire the structure of the genome to initiate and maintain the programs that lead to oncogenic transformation remains poorly understood. Acute promyelocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df0562bb11e661138422c88a22c3ce68
https://pubmed.ncbi.nlm.nih.gov/35450883
https://pubmed.ncbi.nlm.nih.gov/35450883
Autor:
Enrique Blanco, Isabel Espejo, Atefeh Lafzi, Anna Bigas, Marc García-Montolio, Pedro Vizán, Luisa de Andrés-Aguayo, Thomas Graf, Martin Lange, Arantxa Gutierrez, Roshana Thambyrajah, Ana Carretero, Holger Heyn, Luciano Di Croce
Publikováno v:
Science Advances
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Phf19, a Polycomb subunit, controls hematopoietic stem cells identity and differentiation.
Adult hematopoietic stem cells (HSCs) are rare multipotent cells in bone marrow that are responsible for generating all blood cell types. HSCs are a heter
Adult hematopoietic stem cells (HSCs) are rare multipotent cells in bone marrow that are responsible for generating all blood cell types. HSCs are a heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cff41aaa6a09d1ad0a8a98a00d03482
https://ddd.uab.cat/record/252856
https://ddd.uab.cat/record/252856
Autor:
Sergi Aranda, Pedro Vizán, Paola Pisano, Paul Chammas, Michael Wierer, Arantxa Gutierrez, Bernhard Payer, Valerio Di Carlo, Luciano Di Croce, Enrique Blanco, Malte Beringer
Publikováno v:
Molecular Cell. 64:645-658
The cellular plasticity of pluripotent stem cells is thought to be sustained by genomic regions that display both active and repressive chromatin properties. These regions exhibit low levels of gene expression, yet the mechanisms controlling these le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5871b49c87f04df4a19523452b74cd36
https://doi.org/10.1016/j.molcel.2016.10.018
https://doi.org/10.1016/j.molcel.2016.10.018
Autor:
S Capdevila, Cecilia Ballaré, Arantxa Gutierrez, Mareike Roth, Juan Martín-Caballero, Johannes Zuber, Iris Uribesalgo, Santiago Demajo, L Di Croce
Publikováno v:
Oncogene. 33:5501-5510
Acute myeloid leukemia (AML) is frequently linked to epigenetic abnormalities and deregulation of gene transcription, which lead to aberrant cell proliferation and accumulation of undifferentiated precursors. ZRF1, a recently characterized epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65fab45dd6d03c75a708054406c2f63f
https://doi.org/10.1038/onc.2013.501
https://doi.org/10.1038/onc.2013.501
Autor:
Arantxa Gutierrez, Mauro Romanenghi, Gianmaria Frigè, Luciano Di Croce, Pier Giuseppe Pelicci, Matias Soncini, Oronza A. Botrugno, Isabella Pallavicini, Saverio Minucci, Fabio Santoro
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832:114-120
Although epigenetic drugs have been approved for use in selected malignancies, there is significant need for a better understanding of their mechanism of action. Here, we study the action of a clinically approved DNA-methyltransferase inhibitor – d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701987bbaddcb85f0ea98fd7fc0ac7d9
https://doi.org/10.1016/j.bbadis.2012.10.001
https://doi.org/10.1016/j.bbadis.2012.10.001
Autor:
Nuno Miguel Luis, William M. Keyes, Joana Domingues Ribeiro, Alba Mas, Stefania Mejetta, Arantxa Gutierrez, Holger Richly, Lluis Morey, Salvador Aznar Benitah, L Di Croce
Publikováno v:
Oncogene; Vol 32
The reactivation of the INK4-ARF locus, which is epigenetically repressed by Polycomb proteins in healthy cells, is a hallmark of senescence. One mechanism of reactivating Polycomb-silenced genes is mediated by the epigenetic factor ZRF1, which assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2984701335c3e7158a2d51bb8f04044b
Autor:
Francesco Fazi, Arantxa Gutierrez, Marcus Buschbeck, Carmen Brenner, Luciano Di Croce, François Fuks, Saverio Minucci, Lluis Morey, Raffaella Villa, Clara Nervi
Publikováno v:
Molecular and Cellular Biology. 28:5912-5923
In plants, as in mammals, mutations in SNF2-like DNA helicases/ATPases were shown to affect not only chromatin structure but also global methylation patterns, suggesting a potential functional link between chromatin structure and epigenetic marks. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51604ff89f76c70e40aa66823074c224
https://doi.org/10.1128/mcb.00467-08
https://doi.org/10.1128/mcb.00467-08
Autor:
Marcus Buschbeck, Iris Uribesalgo, Arantxa Gutierrez, Saverio Minucci, Andreas Ledl, L Di Croce, Stefan Müller
Publikováno v:
Oncogene. 26:3415-3422
Opposing functions like oncogene and tumor suppressions have been established for c-Myc and promyelocytic leukemia (PML) protein, respectively. Myc is known to inhibit differentiation of hematopoietic precursor cells, and here we report that PML prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a647f90ca30624afaafd9502745a9c
https://doi.org/10.1038/sj.onc.1210128
https://doi.org/10.1038/sj.onc.1210128
Publikováno v:
EMBO reports. 16(1)
Id proteins are dominant-negative regulators within the HLH family of proteins. In embryonic stem cells (ESCs), Id1 and Id3 maintain the pluripotent state by preventing neural differentiation. The Id1-interacting protein Zrf1 plays a crucial role as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faeffa0816784aeedcb9f9defca7c19f
https://pubmed.ncbi.nlm.nih.gov/25361733
https://pubmed.ncbi.nlm.nih.gov/25361733