Vascular‐derived TGF‐β increases in the stem cell niche and perturbs neurogenesis during aging and following irradiation in the adult mouse brain

Autor: Jose R. Pineda, Mathieu Daynac, Alexandra Chicheportiche, Arantxa Cebrian‐Silla, Karine Sii Felice, Jose Manuel Garcia‐Verdugo, François D. Boussin, Marc‐André Mouthon

Publikováno v: EMBO Molecular Medicine, Vol 5, Iss 4, Pp 548-562 (2013)

Abstract Neurogenesis decreases during aging and following cranial radiotherapy, causing a progressive cognitive decline that is currently untreatable. However, functional neural stem cells remained present in the subventricular zone of high dose‐i

Externí odkaz: https://doaj.org/article/5705b7354b2b44e29a1c2a687c53a99c

Comment on 'Impact of neurodegenerative diseases on human adult hippocampal neurogenesis'

Autor: Arturo Alvarez-Buylla, Arantxa Cebrian-Silla, Shawn F. Sorrells, Marcos Assis Nascimento, Mercedes F. Paredes, Jose Manuel Garcia-Verdugo, Zhengang Yang, Eric J. Huang

Publikováno v: Science (New York, N.Y.), vol 376, iss 6590
Science

Terreros-Roncal et al . investigated the impacts of human neurodegeneration on immunostainings assumed to be associated with neurogenesis. However, the study provides no evidence that putative proliferating cells are linked to neurogenesis, that mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef89e88df1295a553730d0400e6264ae
https://escholarship.org/uc/item/4h72j0xm

Nests of dividing neuroblasts sustain interneuron production for the developing human brain

Autor: Mercedes F. Paredes, Cristina Mora, Quetzal Flores-Ramirez, Arantxa Cebrian-Silla, Ashley Del Dosso, Phil Larimer, Jiapei Chen, Gugene Kang, Susana Gonzalez Granero, Eric Garcia, Julia Chu, Ryan Delgado, Jennifer A. Cotter, Vivian Tang, Julien Spatazza, Kirsten Obernier, Jaime Ferrer Lozano, Maximo Vento, Julia Scott, Colin Studholme, Tomasz J. Nowakowski, Arnold R. Kriegstein, Michael C. Oldham, Andrea Hasenstaub, Jose Manuel Garcia-Verdugo, Arturo Alvarez-Buylla, Eric J. Huang

Publikováno v: Science
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Science (New York, N.Y.), vol 375, iss 6579

The human cortex contains inhibitory interneurons derived from the medial ganglionic eminence (MGE), a germinal zone in the embryonic ventral forebrain. How this germinal zone generates sufficient interneurons for the human brain remains unclear. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9084fb37b0972aeb5b788c47a59127
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15501

Author response: Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenesis

Autor: Ricardo Romero Rodriguez, David M. Wu, Benjamin Mansky, Arantxa Cebrian-Silla, Marcos Assis Nascimento, Kirsten Obernier, Daniel A. Lim, José Manuel García-Verdugo, Arturo Alvarez-Buylla, Susana González-Granero, Stephanie A. Redmond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8b0e6e7b6e17cac30f1a33fe6a7da39
https://doi.org/10.7554/elife.67436.sa2

Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenic lineages

Autor: Arantxa Cebrian Silla, Daniel A. Lim, Ricardo Romero Rodriguez, Kirsten Obernier, Stephanie A. Redmond, Arturo Alvarez-Buylla, David M. Wu, Marcos Assis Nascimento, Benjamin Mansky

The ventricular-subventricular zone (V-SVZ) is home to the largest neurogenic niche in the adult mouse brain. Previous work has demonstrated that resident stem cells in different locations within the V-SVZ produce different subtypes of new neurons fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afa60fa8396261eca7a52a635fb23dd1
https://doi.org/10.1101/2021.02.10.430525