Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Aramant, RB"'
Publikováno v:
Radtke, ND; Seiler, MJ; Aramant, RB; Petry, HM; & Pidwell, DJ. (2016). Transplantation of intact sheets of fetal neural retina with its RPE in retinitis pigmentosa patients.. American Journal of Ophthalmology. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/45g3074v
Purpose: To show the safety of transplanting sheets of fetal retina together with its RPE to patients with retinitis pigmentosa. Methods: Sheets of fetal neural retina and RPE together were transplanted into the subretinal space near the fovea unilat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d9da439634306a55918365a785d22148
https://escholarship.org/uc/item/45g3074v
https://escholarship.org/uc/item/45g3074v
Publikováno v:
Woch, G; Aramant, RB; Seiler, MJ; Sagdullaev, BT; & McCall, MA. (2016). Retinal transplants restore visual responses in rats with photoreceptor degeneration.. Investigative Ophthalmology and Visual Science. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6748r94f
PURPOSE. To assess whether transplantation of intact sheets of fetal retina with retinal pigment epithelium (RPE) into a retina with photoreceptor degeneration restores visually evoked responses. METHODS. Sheets of fetal retina with RPE were transpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::941e96b9a02e07971d10dc732ddf853d
http://www.escholarship.org/uc/item/6748r94f
http://www.escholarship.org/uc/item/6748r94f
Autor:
Seiler, MJ, Aramant, RB
Publikováno v:
Seiler, MJ; & Aramant, RB. (2016). Intact sheets of fetal retina transplanted to restore damaged rat retinas.. Investigative Ophthalmology and Visual Science. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2c88p1xk
Investigative ophthalmology & visual science, vol 39, iss 11
Investigative ophthalmology & visual science, vol 39, iss 11
PURPOSE. The aim of this study was to establish a model for morphologic retinal reconstruction after destruction of photoreceptors. METHODS. Rat embryos were prelabeled by injection of bromodeoxyuridine (BrdU) into timed pregnant rats on 2 to 6 conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dbf5645b45925aa8ff855cb847169fb4
http://www.escholarship.org/uc/item/2c88p1xk
http://www.escholarship.org/uc/item/2c88p1xk
Publikováno v:
The European journal of neuroscience, vol 35, iss 11
Seiler, MJ; Jones, BW; Aramant, RB; Yang, PB; Keirstead, HS; & Marc, RE. (2012). Computational molecular phenotyping of retinal sheet transplants to rats with retinal degeneration. European Journal of Neuroscience, 35(11), 1692-1704. doi: 10.1111/j.1460-9568.2012.08078.x. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4x68d31p
Seiler, MJ; Jones, BW; Aramant, RB; Yang, PB; Keirstead, HS; & Marc, RE. (2012). Computational molecular phenotyping of retinal sheet transplants to rats with retinal degeneration. European Journal of Neuroscience, 35(11), 1692-1704. doi: 10.1111/j.1460-9568.2012.08078.x. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4x68d31p
Retinal progenitor sheet transplants have been shown to extend neuronal processes into a degenerating host retina and to restore visual responses in the brain. The aim of this study was to identify cells involved in transplant signals to retinal dege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4ef5ea09d1ce2db43fddb1ed1eeaabc4
https://escholarship.org/uc/item/4x68d31p
https://escholarship.org/uc/item/4x68d31p
Publikováno v:
The European journal of neuroscience, vol 31, iss 3
Seiler, MJ; Aramant, RB; Thomas, BB; Peng, Q; Sadda, SR; & Keirstead, HS. (2010). Visual restoration and transplant connectivity in degenerate rats implanted with retinal progenitor sheets. European Journal of Neuroscience, 31(3), 508-520. doi: 10.1111/j.1460-9568.2010.07085.x. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2np3192b
Seiler, MJ; Aramant, RB; Thomas, BB; Peng, Q; Sadda, SR; & Keirstead, HS. (2010). Visual restoration and transplant connectivity in degenerate rats implanted with retinal progenitor sheets. European Journal of Neuroscience, 31(3), 508-520. doi: 10.1111/j.1460-9568.2010.07085.x. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2np3192b
The aim of this study was to determine whether retinal progenitor layer transplants form synaptic connections with the host and restore vision. Donor retinal sheets, isolated from embryonic day 19 rat fetuses expressing human placental alkaline phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::454f2e90a0fab6cea71cf52b39efc570
https://escholarship.org/uc/item/2np3192b
https://escholarship.org/uc/item/2np3192b
Publikováno v:
The European journal of neuroscience, vol 28, iss 1
Seiler, MJ; Thomas, BB; Chen, Z; Wu, R; Sadda, SR; & Aramant, RB. (2008). Retinal transplants restore visual responses: Trans-synaptic tracing from visually responsive sites labels transplant neurons. European Journal of Neuroscience, 28(1), 208-220. doi: 10.1111/j.1460-9568.2008.06279.x. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7d9054n7
Seiler, MJ; Thomas, BB; Chen, Z; Wu, R; Sadda, SR; & Aramant, RB. (2008). Retinal transplants restore visual responses: Trans-synaptic tracing from visually responsive sites labels transplant neurons. European Journal of Neuroscience, 28(1), 208-220. doi: 10.1111/j.1460-9568.2008.06279.x. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7d9054n7
This study aimed to test the hypothesis that visual responses in the superior colliculus (SC) originate from synaptic connections between fetal retinal transplants and degenerating host retinas. Sheets of embryonic day 19 rat retina expressing human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::22bb6bf9c569aa028469cdc056434760
https://escholarship.org/uc/item/7d9054n7
https://escholarship.org/uc/item/7d9054n7
Publikováno v:
Journal of neuroscience methods, vol 151, iss 2
Thomas, BB; Arai, S; Ikai, Y; Qiu, G; Chen, Z; Aramant, RB; et al.(2006). Retinal transplants evaluated by optical coherence tomography in photoreceptor degenerate rats. Journal of Neuroscience Methods, 151(2), 186-193. doi: 10.1016/j.jneumeth.2005.07.004. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7bs2q2rq
Thomas, BB; Arai, S; Ikai, Y; Qiu, G; Chen, Z; Aramant, RB; et al.(2006). Retinal transplants evaluated by optical coherence tomography in photoreceptor degenerate rats. Journal of Neuroscience Methods, 151(2), 186-193. doi: 10.1016/j.jneumeth.2005.07.004. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7bs2q2rq
Optical coherence tomography (OCT), a non-invasive method, was used for qualitative assessment of fetal retinal sheet transplants by non-invasive imaging. Rhodopsin-mutant S334ter-line-3 rats with fast retinal degeneration (28-37-day old) were transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2778e86f6c90a0049d6cfff73022e046
https://escholarship.org/uc/item/7bs2q2rq
https://escholarship.org/uc/item/7bs2q2rq
Publikováno v:
Journal of neuroscience methods, vol 138, iss 1-2
Thomas, BB; Seiler, MJ; Sadda, SR; Coffey, PJ; & Aramant, RB. (2004). Optokinetic test to evaluate visual acuity of each eye independently. Journal of Neuroscience Methods, 138(1-2), 7-13. doi: 10.1016/j.jneumeth.2004.03.007. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6w77n1h3
Thomas, BB; Seiler, MJ; Sadda, SR; Coffey, PJ; & Aramant, RB. (2004). Optokinetic test to evaluate visual acuity of each eye independently. Journal of Neuroscience Methods, 138(1-2), 7-13. doi: 10.1016/j.jneumeth.2004.03.007. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6w77n1h3
A previously described optokinetic testing apparatus [Nat. Neurosci. 5 (2002) 53] was modified to measure vision in each eye separately for evaluation of monocular treatments. This apparatus consists also of a striped rotating drum. Ca. 170°of the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9d22a17b93b9fd03e4ff1a6ffa20c106
https://escholarship.org/uc/item/6w77n1h3
https://escholarship.org/uc/item/6w77n1h3
Publikováno v:
Experimental eye research, vol 79, iss 3
Arai, S; Thomas, BB; Seiler, MJ; Aramant, RB; Qiu, G; Mui, C; et al.(2004). Restoration of visual responses following transplantation of intact retinal sheets in rd mice. Experimental Eye Research, 79(3), 331-341. doi: 10.1016/j.exer.2004.05.013. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7cx876h8
Arai, S; Thomas, BB; Seiler, MJ; Aramant, RB; Qiu, G; Mui, C; et al.(2004). Restoration of visual responses following transplantation of intact retinal sheets in rd mice. Experimental Eye Research, 79(3), 331-341. doi: 10.1016/j.exer.2004.05.013. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7cx876h8
Purpose. To correlate the functional outcomes with histologic findings following transplantation of fetal retinal sheets in rd mice, and to investigate the mechanisms of visual function restoration. Methods. Twenty-one postnatal day 31-38 rd/rd (C3H/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a270b02454f094a66464a7ca559f3ed5
https://escholarship.org/uc/item/7cx876h8
https://escholarship.org/uc/item/7cx876h8
Publikováno v:
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, vol 238, iss 7
Seiler, MJ; Liu, OL; Cooper, NGF; Callahan, TL; Petry, HM; & Aramant, RB. (2016). Selective photoreceptor damage in albino rats using continuous blue light – a protocol useful for retinal degeneration and transplantation research.. Graefes Archive for Clinical and Experimental Ophthalmology. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/532857p9
Seiler, MJ; Liu, OL; Cooper, NGF; Callahan, TL; Petry, HM; & Aramant, RB. (2016). Selective photoreceptor damage in albino rats using continuous blue light – a protocol useful for retinal degeneration and transplantation research.. Graefes Archive for Clinical and Experimental Ophthalmology. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/532857p9
Purpose: To develop a retinal degeneration model with selective photoreceptor loss and RPE sparing, to be used as recipient for evaluating retinal transplants. Methods: Albino rats were exposed to blue light, continuously, for 1–7 days (24–168 h)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4e8cb3e3a50c83bf18de633840424320
https://escholarship.org/uc/item/532857p9
https://escholarship.org/uc/item/532857p9