Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Aram Parsegian"'
Autor:
Aram Parsegian, M. Julia García-Fuster, Elaine Hebda-Bauer, Stanley J. Watson, Shelly B. Flagel, Huda Akil
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Adolescent drug use reliably predicts increased addiction liability in adulthood, but not all individuals are equally impacted. To explore the biological bases of this differential reactivity to early life drug experience, we used a genetic rat model
Externí odkaz:
https://doaj.org/article/4fb0b1fc3c324177a44c15ff262798f9
Autor:
Paolo Campus, Ignacio R Covelo, Youngsoo Kim, Aram Parsegian, Brittany N Kuhn, Sofia A Lopez, John F Neumaier, Susan M Ferguson, Leah C Solberg Woods, Martin Sarter, Shelly B Flagel
Publikováno v:
eLife, Vol 8 (2019)
Cues in the environment can elicit complex emotional states, and thereby maladaptive behavior, as a function of their ascribed value. Here we capture individual variation in the propensity to attribute motivational value to reward-cues using the sign
Externí odkaz:
https://doaj.org/article/fda98ee97227493e80cc50c7bf11e596
Autor:
Aram Parsegian, M. Julia García-Fuster, Elaine Hebda-Bauer, Stanley J. Watson, Shelly B. Flagel, Huda Akil
While early life drug use reliably predicts addiction liability in adulthood, the molecular mechanism by which this occurs, and the degree genetic predisposition is involved is not known. We used a unique genetic rat model of temperament to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0353f12f49a4b6ba3d6588673ef153e1
https://doi.org/10.1101/2022.07.13.499935
https://doi.org/10.1101/2022.07.13.499935
Autor:
Charlotte Yang, Eman Mubarak, Marin S. Klumpner, Sofia A. Lopez, Paolo Campus, Aram Parsegian, Shelly B. Flagel
Environmental cues attain the ability to guide behavior via learned associations. As predictors, cues can elicit adaptive behavior and lead to valuable resources (e.g., food). For some individuals, however, cues are transformed into incentive stimuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3711881e7281ef780db4d88418da19b2
https://doi.org/10.1101/2020.09.04.283549
https://doi.org/10.1101/2020.09.04.283549
Publikováno v:
Psychopharmacology. 234:1293-1305
Environmental challenges during adolescence, such as drug exposure, can cause enduring behavioral and molecular changes that contribute to life-long maladaptive behaviors, including addiction. Selectively bred high-responder (bHR) and low-responder (
Autor:
Huda Akil, Aram Parsegian, David M. Krolewski, Elaine K. Hebda-Bauer, Foltz M, Kumar, Stanley J. Watson, Brian E. Martin
Transcript labelling in intact tissues using in situ hybridization chain reaction has potential to provide vital spatiotemporal information for molecular characterization of heterogeneous neuronal populations. However, it remains relatively unexplore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299c1ca418b9ebcea5d1bc7abb68d10f
https://doi.org/10.1101/763920
https://doi.org/10.1101/763920
Autor:
Youngsoo Kim, Sofia A. Lopez, Leah C. Solberg Woods, Brittany N Kuhn, Paolo Campus, Martin Sarter, Susan M. Ferguson, Aram Parsegian, Ignacio R. Covelo, Shelly B. Flagel, John F. Neumaier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b746cb6374dcd1240ee34dc2bfcf549
https://doi.org/10.7554/elife.49041.046
https://doi.org/10.7554/elife.49041.046
Autor:
Aram Parsegian, Brian E. Martin, Huda Akil, Stanley J. Watson, Elaine K. Hebda-Bauer, Matthew Foltz, Vivek Kumar, David M. Krolewski
Publikováno v:
Brain Struct Funct
Transcript labeling in intact tissues using in situ hybridization chain reaction has potential to provide vital spatiotemporal information for molecular characterization of heterogeneous neuronal populations. However, large tissue labeling in non-per
Autor:
Brittany N Kuhn, Leah C. Solberg Woods, Ignacio R. Covelo, Sofia A. Lopez, Aram Parsegian, Susan M. Ferguson, Youngsoo Kim, Shelly B. Flagel, Paolo Campus, John F. Neumaier, Martin Sarter
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Cues in the environment can elicit complex emotional states, and thereby maladaptive behavior, as a function of their ascribed value. Here we capture individual variation in the propensity to attribute motivational value to reward-cues using the sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffaa9e3e635be6d52f535a71e4875c78
Autor:
Sofia A. Lopez, Charlotte Yang, Marin S. Klumpner, Shelly B. Flagel, Aram Parsegian, Paolo Campus, Eman Mubarak
Publikováno v:
eNeuro
Environmental cues attain the ability to guide behavior via learned associations. As predictors, cues can elicit adaptive behavior and lead to valuable resources (e.g., food). For some individuals, however, cues are transformed into incentive stimuli