Výsledky vyhledávání - "Araki, Kumiko"

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Additional file 2: of Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo

Autor: Masateru Hiyoshi, Kazu Okuma, Tateyama, Seiji, Takizawa, Kazuya, Masumichi Saito, Kuramitsu, Madoka, Araki, Kumiko, Morishita, Kazuhiro, Okada, Seiji, Yamamoto, Naoki, Arya Biragyn, Yamaguchi, Kazunari, Hamaguchi, Isao

Figure S2. Phenotype of MT-2 cells. Expression of the indicated molecules on MT-2 cells was analyzed by flow cytometry. This analysis showed that MT-2 cells are CD45â CD3â CD4+CD8â . This phenotype of cells was analyzed similarly in samples from h

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Additional file 6: of Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo

Figure S4. Independence of furin expression from induced expression of HTLV-1 Tax. Although expression of Tax was definitely induced by adding Cd2+ to JPX-9 cells (lower panel), expression of furin was not increased as compared with that before addin

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Additional file 5: of Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo

Table S2. Characteristics of HTLV-1-infected individuals from which blood samples were collected to test a correlation between PVLs and expression of furin.

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Additional file 4: of Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo

Figure S3. Therapeutic effects of TARC–PE38 on CD4+CCR4+ cells in HTLV-1-infected humanized mice. To assess the therapeutic effect of TARC–PE38 on HTLV-1-infected cells, peripheral blood was obtained from all the mice. The PBMCs were isolated and

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Additional file 1: of Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo

Figure S1. Viability of MT-2 cells treated with MMC. After MT-2 cells were treated with 50 Îźg/ml MMC, they were cultured in vitro and the number of live cells was counted daily with the standard Trypan-blue exclusion method to check the viability

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Additional file 3: of Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo

Table S1. Detection of MT-2 cells in humanized mice at 2Â weeks post-inoculation with non- or MMC-treated MT-2 cells. Frequencies of MT-2 cells and HTLV-1 PVLs were tested with flow cytometry and quantitative PCR, respectively, in splenocytes and PB

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Akademický článek

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