Zobrazeno 1 - 10
of 2 663
pro vyhledávání: '"Arachidonic acid metabolism"'
Autor:
Jei Kim, Byoung-Soo Shin, Dae-Hyun Kim, Dong-Ick Shin, Seong Hwan Ahn, Jae Guk Kim, Su Hyun Ryu, Hye Rin Moon, Hyun Goo Kang, Hyeseon Jeong, Kyu Sun Yum, Hee-Yun Chae, Do-Hyung Kim, Keunsoo Kang, Jeeyeon Kim
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background Mediators, genomic and epigenomic characteristics involving in metabolism of arachidonic acid by cyclooxygenase (COX) and lipoxygenase (ALOX) and hepatic activation of clopidogrel have been individually suggested as factors associ
Externí odkaz:
https://doaj.org/article/c2b72bdb209e46749e0b1f8e83a54ceb
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background Patients with non‐alcoholic fatty liver disease (NAFLD) often exhibit hepatic steatosis and dyslipidemia. Studies have shown that intestinal microorganisms are closely related to the occurrence of NAFLD and atherosclerosis. Our
Externí odkaz:
https://doaj.org/article/77f3cf5d616a40169b68513dacc1f68e
Autor:
Kaiyue Ma, Lu Sun, Chunxue Jia, Hongqian Kui, Jiaqi Xie, Shidan Zang, Shixin Huang, Jinfeng Que, Chuanxin Liu, Jianmei Huang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionPodophyllotoxin (PPT) is a high-content and high-activity compound extracted from the traditional Chinese medicinal plant Dysosma versipellis (DV) which exhibits various biological activities. However, its severe toxicity limits its use.
Externí odkaz:
https://doaj.org/article/bae340b3bc8347d29657a2f63b519fe0
Publikováno v:
Shipin Kexue, Vol 45, Iss 10, Pp 147-157 (2024)
The aim of this study was to investigate the core components and mechanism of action of Rosa roxburghii fruit flavonoids in the intervention of ulcerative colitis (UC) using network pharmacology and molecular docking. We extracted flavonoids from R.
Externí odkaz:
https://doaj.org/article/b45c6df7ec924f6bb7550d69a66d85b0
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 2, Pp 83-97 (2024)
Abstract Background Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), is a heterogeneous state of chronic intestinal inflammation. Intestinal innate immunity, including innate immune cells, defends against
Externí odkaz:
https://doaj.org/article/cb6d0b6b2dd44c0fb9d69d6995382795
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 14, Iss 2, Pp 135-147 (2024)
Background and Aim: Xuefu Zhuyu decoction (XZD), a traditional Chinese medicinal formula, was firstly recorded in the Qing dynasty of ancient China and previously demonstrated to ameliorate hepatic steatosis. In the present study, the effects of XZD
Externí odkaz:
https://doaj.org/article/9f942400ae054ced8e10c1babffe6402
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33370- (2024)
Background: Dihydroartemisinin (DHA), a derivative of Artemisia annua, has been shown to possess anti-inflammatory properties. Besides, Yes-associated protein 1 (YAP1) plays a crucial role in maintaining liver homeostasis. Methods: This study used Ya
Externí odkaz:
https://doaj.org/article/8cf4b85a41564042b98d5f1645624f6a
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9521 (2024)
In vitro embryonic technology is crucial for improving farm animal reproduction but is hampered by the poor quality of oocytes and insufficient development potential. This study investigated the relationships among changes in the gut microbiota and m
Externí odkaz:
https://doaj.org/article/b3fd835898e1432cb3309a030c35e5e8
Autor:
Dai Lin, Xinyan Fu, Bo Li, Yanzi Huo, Manling Xie, Tong Li, Pingping Zhu, Guobo Li, Fang Huang
Publikováno v:
Journal of Functional Foods, Vol 116, Iss , Pp 106182- (2024)
This study aimed to investigate the metabolites of conjugated linoleic acid (CLA) in vivo from the perspective of metabolomics, so as to reveal the potential mechanism of CLA in lowing blood lipids. 30 male non-adult SD rats were divided into: normal
Externí odkaz:
https://doaj.org/article/f9c98c30639a499c864b3cacea145022