Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aracely Castillo-Venzor"'
Autor:
Oliver M. Dovey, Pedro Madrigal, Paolo Gallipoli, George S. Vassiliou, Haiyang Yun, Cameron S. Osborne, Shuchi Agrawal-Singh, Annalisa Mupo, Shabana Vohra, David Lara-Astiaso, Aracely Castillo-Venzor, Faisal Basheer, Sarah J. Horton, Brian J. P. Huntly, Ludovica Marando, Malgorzata Gozdecka, Eshwar Meduri, Carsten Müller-Tidow, Daniel Sasca, George Giotopoulos, Xiaonan Wang, Nisha Narayan
Publikováno v:
Nature Genetics. 53:1443-1455
Altered transcription is a cardinal feature of acute myeloid leukemia (AML); however, exactly how mutations synergize to remodel the epigenetic landscape and rewire three-dimensional DNA topology is unknown. Here, we apply an integrated genomic appro
Autor:
Aracely Castillo-Venzor, Christopher A Penfold, Michael D Morgan, Walfred WC Tang, Toshihiro Kobayashi, Frederick CK Wong, Sophie Bergmann, Erin Slatery, Thorsten E Boroviak, John C Marioni, M Azim Surani
Publikováno v:
Life Science Alliance. 6:e202201706
Human germline-soma segregation occurs during weeks 2-3 in gastrulating embryos. While direct studies are hindered, here we investigate the dynamics of human primordial germ cell (PGCs) specification using in vitro models with temporally resolved sin
Autor:
Walfred W. C. Tang, Masumi Hirabayashi, Naoaki Mizuno, Michael D Morgan, Yasuyuki Osada, Hiromitsu Nakauchi, Christopher A. Penfold, Aracely Castillo-Venzor, Masao Hirao, M. Azim Surani, Toshihiro Kobayashi, Hideyuki Sato, Fumika Yoshida
Publikováno v:
Cell reports. 37(2)
Summary Rabbit embryos develop as bilaminar discs at gastrulation as in humans and most other mammals, whereas rodents develop as egg cylinders. Primordial germ cells (PGCs) appear to originate during gastrulation according to many systematic studies
Autor:
Walfred W C, Tang, Aracely, Castillo-Venzor, Wolfram H, Gruhn, Toshihiro, Kobayashi, Christopher A, Penfold, Michael D, Morgan, Dawei, Sun, Naoko, Irie, M Azim, Surani
Publikováno v:
Nature cell biology. 24(4)
Germline-soma segregation is a fundamental event during mammalian embryonic development. Here we establish the epigenetic principles of human primordial germ cell (hPGC) development using in vivo hPGCs and stem cell models recapitulating gastrulation
Autor:
George Giotopoulos, Shabana Vohra, Carsten Müller-Tidow, Faisal Basheer, Annalisa Mupo, Daniel Sasca, Paolo Gallipoli, Eshwar Meduri, Sarah J. Horton, Ludovica Marando, Malgorzata Gozdecka, Oliver M. Dovey, Xiaonan Wang, George S. Vassiliou, Shuchi Agrawal-Singh, Cameron S. Osborne, Aracely Castillo-Venzor, Brian J. P. Huntly, Haiyang Yun
Altered transcription is a cardinal feature of acute myeloid leukemia (AML), however, exactly how mutations synergize to remodel the epigenetic landscape and rewire 3-Dimensional (3-D) DNA topology is unknown. Here we apply an integrated genomic appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c296f929ce2ad4d8f3c2ad117276b1a
https://doi.org/10.1101/2020.03.20.000059
https://doi.org/10.1101/2020.03.20.000059
Autor:
Martesa, Tantra, Christian, Hammer, Anne, Kästner, Liane, Dahm, Martin, Begemann, Chiranjeevi, Bodda, Kurt, Hammerschmidt, Ina, Giegling, Beata, Stepniak, Aracely, Castillo Venzor, Bettina, Konte, Begun, Erbaba, Annette, Hartmann, Asieh, Tarami, Walter, Schulz-Schaeffer, Dan, Rujescu, Ashraf U, Mannan, Hannelore, Ehrenreich
Publikováno v:
EMBO Molecular Medicine
The X-chromosomal MECP2/Mecp2 gene encodes methyl-CpG-binding protein 2, a transcriptional activator and repressor regulating many other genes. We discovered in male FVB/N mice that mild (∼50%) transgenic overexpression of Mecp2 enhances aggression