Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Arabinda Guha"'
Autor:
Milton Mendlowitz, Maria Rossikhina, Juan J. Badimon, John T. Fallon, Arabinda Guha, Peter L.A. Giesen, Mark B. Taubman, Yale Nemerson, Billie Fyfe, Mercè Roqué
Publikováno v:
Thrombosis and Haemostasis. 83:622-628
SummaryTissue factor (TF), the initiator of coagulation, has been implicated as a critical mediator of arterial thrombosis. Previous studies have demonstrated that TF is rapidly induced in the normal rodent arterial wall by balloon injury, but is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99301c31f005d370a3de495c3d0a853a
https://doi.org/10.1055/s-0037-1613874
https://doi.org/10.1055/s-0037-1613874
Autor:
William H. Konigsberg, Arabinda Guha, David Banner, Yale Nemerson, Fritz K. Winkler, Christiana Chène, Allan D'Arcy, Daniel Kirchhofer
Publikováno v:
Nature. 380:41-46
Blood coagulation is initiated when tissue factor binds to coagulation factor VIIa to give an enzymatically active complex which then activates factors IX and X, leading to thrombin generation and clot formation. We have determined the crystal struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17d84d8a22b8168aa9de3ab96755fe2
https://doi.org/10.1038/380041a0
https://doi.org/10.1038/380041a0
Publikováno v:
Thrombosis and Haemostasis. 76:361-368
SummaryIn an attempt to define sequence elements in human and mouse tissue factor (TF) that are responsible for the species specificity observed in their interaction with human factor VIIa (HVIIa), we constructed human-mouse chimeric TF cDNAs, insert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b28ee807127eb114a4c56b0d7bf6864
https://doi.org/10.1055/s-0038-1650584
https://doi.org/10.1055/s-0038-1650584
Autor:
Jonathan D. Marmur, Arabinda Guha, Maria Rossikhina, Milton Mendlowitz, V Friedrich, Billie Fyfe, Mark B. Taubman, Yale Nemerson
Publikováno v:
Journal of Clinical Investigation. 91:2253-2259
Tissue factor (TF) is a major activator of the coagulation cascade and may play a role in initiating thrombosis after intravascular injury. To investigate whether medial vascular smooth muscle provides a source of TF following arterial injury, the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694844898a30812e23858504fe262b57
https://doi.org/10.1172/jci116452
https://doi.org/10.1172/jci116452
Autor:
Yale Nemerson, C.-L. Rosenfield, Jonathan D. Marmur, Mark B. Taubman, Arabinda Guha, S. Nichtberger
Publikováno v:
Journal of Clinical Investigation. 91:547-552
Tissue factor (TF) is a low molecular weight glycoprotein that initiates the clotting cascade and is considered to be a major regulator of coagulation, hemostasis, and thrombosis. TF is not expressed in the intima or media of normal adult blood vesse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23c241812bffa1bccbbfbc8c3dbddd2
https://doi.org/10.1172/jci116234
https://doi.org/10.1172/jci116234
Autor:
Singanallore V. Thiruvikraman, J. B. A. Ross, Konigsberg William H, Yale Nemerson, Tsung-Chung Lin, Evan L. Waxman, Thomas M. Laue, Arabinda Guha
Publikováno v:
Biochemistry. 31:3998-4003
We find that the isolated, extracellular domain of tissue factor (TF1-218; sTF) exhibits only 4% of the activity of wild-type transmembrane TF (TF1-263) in an assay that measures the conversion of factor X to Xa by the TF:VIIa complex. Further, the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c069adcd550164d87f1cce89cbb6a6a7
https://doi.org/10.1021/bi00131a015
https://doi.org/10.1021/bi00131a015
Autor:
Xiaodong Zhou, Wayne A. Miller, Yale Nemerson, Ronald R Bach, Charles J. Lockwood, Arabinda Guha
Publikováno v:
American Journal of Obstetrics and Gynecology. 165:1335-1341
A primary clinical manifestation of amniotic fluid embolism is coagulopathy. Prior studies have identified a poorly characterized yet potent procoagulant property in amniotic fluid that increases with gestational age. One possible source of procoagul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960a0fd2e8304b156c982c877e6ce510
https://doi.org/10.1016/0002-9378(91)90363-v
https://doi.org/10.1016/0002-9378(91)90363-v
Autor:
Singanallore V. Thiruvikraman, Longhua Ma, Arabinda Guha, John Roboz, Tsonghui Wang, Glen Seaman
Publikováno v:
Rapid communications in mass spectrometry : RCM. 10(11)
Digoxigenin ester (Dig) derivatives of coagulation factors VIIa and X facilitate staining studies to localize tissue factor activity in human atherosclerotic plaques. The larger the number of attached Dig units the easier it is to form highly visual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d914e7afc5788be3a51d5bdd99d86e
https://pubmed.ncbi.nlm.nih.gov/8805845
https://pubmed.ncbi.nlm.nih.gov/8805845
Autor:
William H. Konigsberg, Francis Vilbois, Christiane Chène, Yale Nemerson, David Banner, Daniel Kirchhofer, Arabinda Guha, Allan D'Arcy
Publikováno v:
Proteins. 22(4)
Exposure of blood to tissue factor leads to the formation of a high affinity tissue factor/factor VIIa complex which initiates blood coagulation. As a first step toward obtaining structural information of this enzyme system, a complex of active-site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d01c9ebe5bba3c4305cdf7979f10a2
https://pubmed.ncbi.nlm.nih.gov/7479715
https://pubmed.ncbi.nlm.nih.gov/7479715
Autor:
Joan Gil, Xiao-Xuan Wu, Jacob H. Rand, Seth Guller, Arabinda Guha, Charles J. Lockwood, Jonathan Scher
Publikováno v:
American journal of obstetrics and gynecology. 171(6)
The mechanism by which antiphospholipid antibodies are associated with pregnancy loss and thromboembolic conditions has yet to be elucidated. Annexin-V, an anticoagulant phospholipid-binding protein, is normally present in syncytiotrophoblasts lining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55202a89a8a0a1c99216504cf35c43b
https://pubmed.ncbi.nlm.nih.gov/7802069
https://pubmed.ncbi.nlm.nih.gov/7802069