Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Arabela A. Grigorescu"'
Autor:
Xu Han, Yang Mei, Rama K. Mishra, Honghao Bi, Atul D. Jain, Gary E. Schiltz, Baobing Zhao, Madina Sukhanova, Pan Wang, Arabela A. Grigorescu, Patricia C. Weber, John J. Piwinski, Miguel A. Prado, Joao A. Paulo, Len Stephens, Karen E. Anderson, Charles S. Abrams, Jing Yang, Peng Ji
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
Myeloproliferative neoplasms (MPNs) are characterized by the activated JAK2/STAT pathway. Pleckstrin-2 (Plek2) is a downstream target of the JAK2/STAT5 pathway and is overexpressed in patients with MPNs. We previously revealed that Plek2 plays critic
Externí odkaz:
https://doaj.org/article/2701d1efe9e540b6893f0cff3edaf376
Autor:
Daniela Matei, Zhong-Yin Zhang, Constandina Arvanitis, Gary E. Schiltz, Lan Chen, Nkechiyere G. Nwani, Arabela A. Grigorescu, Salvatore Condello, Sheng Zhang, Bakhtiyor Yakubov, Livia Elena Sima
Materials, methods; Figure S1. 1H NMR spectrum of MT-1; Figure S2. 1H NMR spectrum of MT-2; Figure S3. 1H NMR spectrum of MT-3; Figure S4. 1H NMR spectrum of MT-4; Figure S5. 1H NMR spectrum of MT-5; Figure S6. 1H NMR spectrum of MT-6; Figure S7. Ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e12d28746f00e635fcc5260dbb111a4
https://doi.org/10.1158/1535-7163.22505841
https://doi.org/10.1158/1535-7163.22505841
Autor:
Daniela Matei, Zhong-Yin Zhang, Constandina Arvanitis, Gary E. Schiltz, Lan Chen, Nkechiyere G. Nwani, Arabela A. Grigorescu, Salvatore Condello, Sheng Zhang, Bakhtiyor Yakubov, Livia Elena Sima
Tissue transglutaminase (TG2) is a multifunctional protein with enzymatic, GTP-ase, and scaffold properties. TG2 interacts with fibronectin (FN) through its N-terminus domain, stabilizing integrin complexes, which regulate cell adhesion to the matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56053471ec81d270f699ecb855dec8b2
https://doi.org/10.1158/1535-7163.c.6538218.v1
https://doi.org/10.1158/1535-7163.c.6538218.v1
Autor:
Lakshmi R. Bollu, Prashant V. Bommi, Paige J. Monsen, Lijie Zhai, Kristen L. Lauing, April Bell, Miri Kim, Erik Ladomersky, Xinyu Yang, Leonidas C. Platanias, Daniela E. Matei, Marcelo G. Bonini, Hidayatullah G. Munshi, Rintaro Hashizume, Jennifer D. Wu, Bin Zhang, Charles David James, Peiwen Chen, Masha Kocherginsky, Craig Horbinski, Michael D. Cameron, Arabela A. Grigorescu, Bakhtiar Yamini, Rimas V. Lukas, Gary E. Schiltz, Derek A. Wainwright
Publikováno v:
Journal of medicinal chemistry. 65(23)
Indoleamine 2,3-dioxygenase 1 (IDO1) is a potent immunosuppressive enzyme that inhibits the antitumor immune response through both tryptophan metabolism and non-enzymatic functions. To date, most IDO1-targeted approaches have focused on inhibiting tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1056cfbddd37cd845aa59f9b40770418
https://pubmed.ncbi.nlm.nih.gov/36410047
https://pubmed.ncbi.nlm.nih.gov/36410047
Autor:
Sasha B. Ebrahimi, Devleena Samanta, Benjamin E. Partridge, Caroline D. Kusmierz, Ho Fung Cheng, Arabela A. Grigorescu, Jorge L. Chávez, Peter A. Mirau, Chad A. Mirkin
Publikováno v:
Angew Chem Int Ed Engl
The ability of aptamers to recognize a variety of different molecules has fueled their emergence as effective recognition agents to probe complex media and cells. Many detection strategies necessitate an aptamer binding to its target to result in a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a120d126c9738ca4fd9900bc356434
https://doi.org/10.1002/anie.202103440
https://doi.org/10.1002/anie.202103440
Autor:
Lakshmi Bollu, Prashant V. Bommi, Paige J. Monsen, Lijie Zhai, Kristen L. Lauing, April Bell, Miri Kim, Erik Ladomersky, Leonidas C. Platanias, Daniela E. Matei, Marcelo G. Bonini, Hidayatullah G. Munshi, Rintaro Hashizume, Jennifer D. Wu, Bin Zhang, C. David James, Peiwen Chen, Masha Kocherginsky, Craig Horbinski, Michael D. Cameron, Arabela A. Grigorescu, Bakhtiar Yamini, Rimas V. Lukas, Gary E. Schiltz, Derek Alan Wainwright
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3047897b4e9019e4fdeb869d06cf646
https://doi.org/10.2139/ssrn.4081515
https://doi.org/10.2139/ssrn.4081515
Autor:
Lan Chen, Sheng Zhang, Constandina Arvanitis, Nkechiyere G. Nwani, Daniela Matei, Bakhtiyor Yakubov, Livia Elena Sima, Arabela A. Grigorescu, Zhong Yin Zhang, Gary E. Schiltz, Salvatore Condello
Publikováno v:
Mol Cancer Ther
Tissue transglutaminase (TG2) is a multifunctional protein with enzymatic, GTP-ase, and scaffold properties. TG2 interacts with fibronectin (FN) through its N-terminus domain, stabilizing integrin complexes, which regulate cell adhesion to the matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2179128c0f554416ae96fc0e756dc0c1
https://pubmed.ncbi.nlm.nih.gov/31015308
https://pubmed.ncbi.nlm.nih.gov/31015308
Autor:
Paul J. Sapienza, Tianyi Niu, Michael R. Kurpiewski, Arabela A. Grigorescu, Linda Jen-Jacobson
Publikováno v:
Journal of Molecular Biology. 426:84-104
As a novel approach to the structural and functional properties that give rise to extremely stringent sequence specificity in protein-DNA interactions, we have exploited “promiscuous” mutants of EcoRI endonuclease to study the detailed mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a268e074e8d026dc8e0480573ddca10e
https://doi.org/10.1016/j.jmb.2013.09.005
https://doi.org/10.1016/j.jmb.2013.09.005
Publikováno v:
Archives of Biochemistry and Biophysics. 537:176-184
We obtained Cx1 from a commercial supplier, whose catalog listed it as a β-xylosidase of glycoside hydrolase family 43. NMR experiments indicate retention of anomeric configuration in its reaction stereochemistry, opposing the assignment of GH43, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35698208ca0958f6e29104b429826ef0
https://doi.org/10.1016/j.abb.2013.07.020
https://doi.org/10.1016/j.abb.2013.07.020
Autor:
Charles C. Lee, J. Rose Stoller, Kurt Wagschal, Douglas B. Jordan, Victor J. Chan, Arabela A. Grigorescu
Publikováno v:
Molecular biotechnology. 58(7)
D-galacturonic acid is a potential platform chemical comprising the principal component of pectin in the citrus processing waste stream. Several enzyme activities are required for the enzymatic production of galacturonic acid from pectin, including e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ca8b21e0e93f84251befa69795e800
https://pubmed.ncbi.nlm.nih.gov/27209035
https://pubmed.ncbi.nlm.nih.gov/27209035