Targeting the Sirtuin-1/PPAR-Gamma Axis, RAGE/HMGB1/NF-κB Signaling, and the Mitochondrial Functions by Canagliflozin Augments the Protective Effects of Levodopa/Carbidopa in Rotenone-Induced Parkinson's Disease.

Autor: Elkady MA; Pharmacology Department, Faculty of Medicine, Tanta University, Tanta 31527, Egypt., Kabel AM; Pharmacology Department, Faculty of Medicine, Tanta University, Tanta 31527, Egypt., Dawood LM; Medical Biochemistry Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt., Helal AI; Department of Histology and Cell Biology, Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh 33516, Egypt., Borg HM; Physiology Department, Faculty of Medicine, Kafrelsheikh University, Kafr El-Shaikh 33516, Egypt., Atia HA; Department of Pharmacology and Toxicology, College of Pharmacy, University of Hail, Hail 2440, Saudi Arabia.; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Al-Azhar University, Cairo 35527, Egypt., Sabry NM; Clinical Oncology Department, Faculty of Medicine, Tanta University, Tanta 31527, Egypt., Moustafa NM; Medical Microbiology & Immunology Department, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.; Basic Medical Science Department, College of Medicine, Dar Al Uloom University, Riyadh 13314, Saudi Arabia., Arafa EA; College of Pharmacy and Health Sciences, Ajman University, Ajman 346, United Arab Emirates.; Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman 346, United Arab Emirates., Alsufyani SE; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia., Arab HH; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.

Publikováno v: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2024 Oct 14; Vol. 60 (10). Date of Electronic Publication: 2024 Oct 14.

Omarigliptin/rosinidin combination ameliorates cyclophosphamide-induced lung toxicity in rats: The interaction between glucagon-like peptide-1, TXNIP/NLRP3 inflammasome signaling, and PI3K/Akt/FoxO1 axis.

Autor: Abd Elmaaboud MA; Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt., Kabel AM; Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt. Electronic address: ahmed.kabal@med.tanta.edu.eg., Borg HM; Physiology Department, Faculty of Medicine, Kafrelsheikh University, Kafr El-Shaikh 33516, Egypt., Magdy AA; Anesthesia and ICU Department, Faculty of Medicine, Tanta University, Tanta 31527, Egypt., Kabel SM; Zoology Department, Faculty of Science, Tanta University, Tanta 31527, Egypt., Arafa EA; College of Pharmacy and Health Sciences, Ajman University, Ajman 346, United Arab Emirates; Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman 346, United Arab Emirates., Alsufyani SE; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia., Arab HH; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Aug; Vol. 177, pp. 117026. Date of Electronic Publication: 2024 Jun 26.

Serum lncRNAs TUG1, H19, and NEAT1 and their target miR-29b/SLC3A1 axis as possible biomarkers of preeclampsia: Potential clinical insights.

Autor: Senousy MA; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt., Shaker OG; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, Egypt., Elmaasrawy AHZ; Department of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Zagazig, Egypt., Ashour AM; Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al Qura University, P.O. Box 13578, Makkah, 21955, Saudi Arabia., Alsufyani SE; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia., Arab HH; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia., Ayeldeen G; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, Egypt.

Publikováno v: Non-coding RNA research [Noncoding RNA Res] 2024 Jun 08; Vol. 9 (4), pp. 995-1008. Date of Electronic Publication: 2024 Jun 08 (Print Publication: 2024).

Targeting Autophagy, Apoptosis, and Oxidative Perturbations with Dapagliflozin Mitigates Cadmium-Induced Cognitive Dysfunction in Rats.

Autor: Arab HH; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Eid AH; Department of Pharmacology, Egyptian Drug Authority (EDA)-Formerly NODCAR, Giza 12654, Egypt., Alsufyani SE; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia., Ashour AM; Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al Qura University, P.O. Box 13578, Makkah 21955, Saudi Arabia., El-Sheikh AAK; Basic Health Sciences Department, College of Medicine, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia., Darwish HW; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 11451, Riyadh 11451, Saudi Arabia., Sabry FM; Department of Pharmacology, Egyptian Drug Authority (EDA)-Formerly NODCAR, Giza 12654, Egypt.

Publikováno v: Biomedicines [Biomedicines] 2023 Nov 08; Vol. 11 (11). Date of Electronic Publication: 2023 Nov 08.

Targeting Autophagy, Apoptosis, and SIRT1/Nrf2 Axis with Topiramate Underlies Its Neuroprotective Effect against Cadmium-Evoked Cognitive Deficits in Rats.

Autor: Arab HH; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Eid AH; Department of Pharmacology, Egyptian Drug Authority (EDA)-Formerly NODCAR, Giza 12654, Egypt., Yahia R; Department of Pharmacology, Egyptian Drug Authority (EDA)-Formerly NODCAR, Giza 12654, Egypt., Alsufyani SE; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia., Ashour AM; Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al Qura University, P.O. Box 13578, Makkah 21955, Saudi Arabia., El-Sheikh AAK; Basic Health Sciences Department, College of Medicine, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia., Darwish HW; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 11451, Riyadh 11451, Saudi Arabia., Saad MA; Department of Pharmaceutical Sciences, College of Pharmacy, Gulf Medical University, Ajman 4184, United Arab Emirates.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Al-Shorbagy MY; Department of Pharmaceutical Sciences, College of Pharmacy, Gulf Medical University, Ajman 4184, United Arab Emirates.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Masoud MA; Department of Pharmacology, Egyptian Drug Authority (EDA)-Formerly NODCAR, Giza 12654, Egypt.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Aug 29; Vol. 16 (9). Date of Electronic Publication: 2023 Aug 29.