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Publikováno v:
American Journal of Hypertension. 16:708-714
Background Eicosapentaenoic acid is a fish oil fatty acid that has been shown to decrease blood pressure (BP) in humans. The mechanism by which this fatty acid produces this effect is unknown. Angiotensin II increases BP by inducing vasoconstriction
Autor:
Niloufar Bibak, Renato Rosseto, and Ara Gabrielian, Joseph Hajdu, Trishul Shah, Rosemarie DeOcampo
Publikováno v:
The Journal of organic chemistry. 72(5)
A new stereoselective synthesis of lysophosphatidylcholines is reported. The synthesis is based upon (1) the use of 3-p-toluenesulfonyl-sn-glycerol to provide the stereocenter for construction of the optically active lysophospholipid molecule, (2) te