Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ara B. Hwang"'
Autor:
Dongyeop Lee, Hyun-Jun Nam, Chanhee Kang, Jooyeon Sohn, Malene Hansen, Linnea M Adams, Yujin Lee, Eun Ji Kim, Seung-Yeol Park, Murat Artan, Dae-Eun Jeong, Dong Jin Moon, Wooseon Hwang, Seung-Jae Lee, Joo-Yeon Yoo, Mihwa Seo, Jeonghun Yeom, Yoonji Jung, Ozlem Altintas, Youngjae Ryu, Sang Ki Park, Cheolju Lee, Keunhee Seo, Sanguk Kim, Chang Man Ha, Seong Kyu Han, Nari Kim, Ara B. Hwang, Sungeun Ju
Publikováno v:
Science Advances
Description
MON-2, which mediates Golgi-endosome trafficking, mediates mitochondrial inhibition–induced longevity by enhancing autophagy.
The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects
MON-2, which mediates Golgi-endosome trafficking, mediates mitochondrial inhibition–induced longevity by enhancing autophagy.
The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects
Autor:
Manmeet H. Raval, Pin-Chung Cheng, Nicholas Guardino, Sanjana Ahsan, Hao Zhou, Rajiv Lochan Tiwari, Lu Wang, Andrew Chareunsouk, Maxwell Ederer, Ara B. Hwang, Matt Ellenberger, Rob Pepin, Daniel Raftery, Daniel Promislow, Keyue Shen, Andrew S. Brack, Joseph T. Rodgers
Decline in the skeletal muscle stem cell (MuSC) function is a major contributor to age-associated impairments in muscle regeneration and function. The ability of MuSCs to activate (i.e. exit quiescence, enter the cell cycle, and divide) following inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d131a18ef953be98d7b655f1ee9d7b
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Murine muscle stem cells (MuSCs) experience a transition from quiescence to activation that is required for regeneration, but it remains unknown if the trajectory and dynamics of activation change with age. Here, we use time-lapse imaging and single
Murine muscle stem cells (MuSCs) experience a transition from quiescence to activation that is required for regeneration, but it remains unclear if the transition states and rates of activation are uniform across cells, or how features of this proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856d0a2898a82955abd3e7b8b66d6994
Autor:
Murat Artan, Seung-Jae Lee, Seung Hyun Han, Sangsoon Park, Ara B. Hwang, Kyong-Tai Kim, Yoonji Jung, Wonsik Shin, Hae-Eun H. Park
Publikováno v:
Science Advances
A conserved protein kinase VRK-1 increases life span by activating a key energy sensor AMPK in the roundworm C. elegans.
Vaccinia virus–related kinase (VRK) is an evolutionarily conserved nuclear protein kinase. VRK-1, the single Caenorhabditi
Vaccinia virus–related kinase (VRK) is an evolutionarily conserved nuclear protein kinase. VRK-1, the single Caenorhabditi
Autor:
Ara B, Hwang, Andrew S, Brack
Publikováno v:
Current topics in developmental biology. 126
Satellite cells (SCs) are a population of muscle-resident stem cells that are essential for efficient tissue repair. SCs reside in a relatively quiescent state during normal tissue turnover, but are activated in response to injury through the microen
Autor:
Andrew S. Brack, Ara B. Hwang
Satellite cells (SCs) are a population of muscle-resident stem cells that are essential for efficient tissue repair. SCs reside in a relatively quiescent state during normal tissue turnover, but are activated in response to injury through the microen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::021c28ad09bb0dee4b4a28261e4cd533
https://doi.org/10.1016/bs.ctdb.2017.08.008
https://doi.org/10.1016/bs.ctdb.2017.08.008
Publikováno v:
Aging (Albany NY)
The second International Symposium on the Genetics of Aging and Life History was held at the campus of Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, South Korea, from May 14 to 16, 2014. Many leading scientists in the field of a
Autor:
Yujin Lee, Hyung-Jun Kim, Joo-Yeon Yoo, Heehwa G. Son, Mihwa Seo, Dongyeop Lee, Wooseon Hwang, Young Min Oh, Jay-Hyun Jo, Jee-Eun Lee, Sunyoung Hwang, Keunhee Seo, Ara B. Hwang, Seung-Jae Lee, Youngjae Ryu, Dae-Eun Jeong, Chang Man Ha, Murat Artan, Haeshim Baek
Mitochondria play key roles in cellular immunity. How mitochondria contribute to organismal immunity remains poorly understood. Here, we show that HSP‐60/HSPD1, a major mitochondrial chaperone, boosts anti‐bacterial immunity through the up‐regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36697e6deeea6faa3501bec21d463923
https://europepmc.org/articles/PMC5391144/
https://europepmc.org/articles/PMC5391144/
Publikováno v:
Current Genomics
Mitochondria are essential for various biological processes including cellular energy production. The oxidative stress theory of aging proposes that mitochondria play key roles in aging by generating reactive oxygen species (ROS), which indiscriminat