Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content.

Autor: Papes F; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil. papesf@unicamp.br.; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA. papesf@unicamp.br.; Center for Medicinal Chemistry, University of Campinas, Campinas, Sao Paulo, 13083-886, Brazil. papesf@unicamp.br., Camargo AP; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil.; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil.; Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., de Souza JS; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Carvalho VMA; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil.; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil., Szeto RA; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., LaMontagne E; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Teixeira JR; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil.; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil., Avansini SH; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; School of Medical Sciences, University of Campinas, Campinas, Sao Paulo, 13083-887, Brazil., Sánchez-Sánchez SM; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Nakahara TS; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil.; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil., Santo CN; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil.; Center for Medicinal Chemistry, University of Campinas, Campinas, Sao Paulo, 13083-886, Brazil.; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil., Wu W; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Yao H; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Araújo BMP; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, Sao Paulo, 13083-862, Brazil., Velho PENF; School of Medical Sciences, University of Campinas, Campinas, Sao Paulo, 13083-887, Brazil., Haddad GG; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Rady Children's Hospital, San Diego, CA, 92123, USA., Muotri AR; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA. muotri@ucsd.edu.; Rady Children's Hospital, San Diego, CA, 92123, USA. muotri@ucsd.edu.; Department of Cellular & Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA. muotri@ucsd.edu.; Kavli Institute for Brain and Mind, University of California San Diego, La Jolla, CA, 92093, USA. muotri@ucsd.edu.; Center for Academic Research and Training in Anthropogeny (CARTA) and Archealization (ArchC), University of California San Diego, La Jolla, CA, 92093, USA. muotri@ucsd.edu.

Publikováno v: Nature communications [Nat Commun] 2022 May 02; Vol. 13 (1), pp. 2387. Date of Electronic Publication: 2022 May 02.