Polμ deficiency increases resistance to oxidative damage and delays liver aging.

Autor: Beatriz Escudero, Daniel Lucas, Carmen Albo, Suveera Dhup, Jeff W Bacher, Aránzazu Sánchez-Muñoz, Margarita Fernández, José Rivera-Torres, Rosa M Carmona, Encarnación Fuster, Candelas Carreiro, Raquel Bernad, Manuel A González, Vicente Andrés, Luis Blanco, Enrique Roche, Isabel Fabregat, Enrique Samper, Antonio Bernad

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e93074 (2014)

Polμ is an error-prone PolX polymerase that contributes to classical NHEJ DNA repair. Mice lacking Polμ (Polμ(-/-)) show altered hematopoiesis homeostasis and DSB repair and a more pronounced nucleolytic resection of some V(D)J junctions. We previ

Externí odkaz: https://doaj.org/article/3950526dbb8e41a6824b67942cf9dee8

Polμ Deficiency Increases Resistance to Oxidative Damage and Delays Liver Aging

Autor: Isabel Fabregat, Carmen Albo, José Rivera-Torres, Candelas Carreiro, Rosa María Carmona, Vicente Andrés, Suveera Dhup, Margarita Fernández, Aránzazu Sánchez-Muñoz, Jeffery W. Bacher, Encarnación Fuster, Beatriz Escudero, Enrique Roche, Enrique Samper, Raquel Bernad, Manuel A. González, Luis Blanco, Antonio Bernad, Daniel Lucas

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e93074 (2014)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya

Polμ is an error-prone PolX polymerase that contributes to classical NHEJ DNA repair. Mice lacking Polm (Polμ-/-) show altered hematopoiesis homeostasis and DSB repair and a more pronounced nucleolytic resection of some V(D)J junctions. We previous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d3c570fbb18deca1b124fb606554df
https://doi.org/10.1371/journal.pone.0093074