Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Arántzazu Alfranca"'
Autor:
Luis San-Jose Manso, Arantzazu Alfranca, Ignacio Moreno-Pérez, María Ruiz-Vico, Clara Velasco, Patricia Toquero, María Pacheco, Almudena Zapatero, Diego Aldave, Guillermo Celada, Eduardo Albers, María-Dolores Fenor de la Maza, Jorge García, Elena Castro, David Olmos, Ramón Colomer, Nuria Romero-Laorden
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Tumor immune microenvironment (TIME) plays a key role to understand how tumors respond to prostate cancer (PC) therapies and potential mechanisms of resistance. Previous research has suggested that specific genomic aberrations, such as microsatellite
Externí odkaz:
https://doaj.org/article/84a97d87cbd74ed5aa219c786b306597
Autor:
Ilya Tsukalov, Ildefonso Sánchez-Cerrillo, Olga Rajas, Elena Avalos, Gorane Iturricastillo, Laura Esparcia, María José Buzón, Meritxell Genescà, Camila Scagnetti, Olga Popova, Noa Martin-Cófreces, Marta Calvet-Mirabent, Ana Marcos-Jimenez, Pedro Martínez-Fleta, Cristina Delgado-Arévalo, Ignacio de los Santos, Cecilia Muñoz-Calleja, María José Calzada, Isidoro González Álvaro, José Palacios-Calvo, Arantzazu Alfranca, Julio Ancochea, Francisco Sánchez-Madrid, Enrique Martin-Gayo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Increased recruitment of transitional and non-classical monocytes in the lung during SARS-CoV-2 infection is associated with COVID-19 severity. However, whether specific innate sensors mediate the activation or differentiation of monocytes i
Externí odkaz:
https://doaj.org/article/063c0aefc27e417fbe9da8c04405f147
Autor:
Pedro Martínez-Fleta, Esther F. Vicente-Rabaneda, Ana Triguero-Martínez, Emilia Roy-Vallejo, Miren Uriarte-Ecenarro, Francisco Gutiérrez-Rodríguez, Patricia Quiroga-Colina, Ana Romero-Robles, Nuria Montes, Noelia García-Castañeda, Gina P. Mejía-Abril, Jesús A. García-Vadillo, Irene Llorente-Cubas, José R. Villagrasa, José M. Serra López-Matencio, Julio Ancochea, Ana Urzainqui, Laura Esparcia-Pinedo, Arantzazu Alfranca, Hortensia de la Fuente, Rosario García-Vicuña, Francisco Sánchez-Madrid, Isidoro González-Álvaro, Santos Castañeda
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract B and T cell responses were evaluated in patients with rheumatoid arthritis (RA) or psoriatic arthritis (PsA) after 1 or 2 weeks of methotrexate (MTX) withdrawal following each COVID-19 vaccine dose and compared with those who maintained MTX
Externí odkaz:
https://doaj.org/article/68cb81a827cf4cafad508bc550296c46
Autor:
Virginia Meca-Lallana, Laura Esparcia-Pinedo, Clara Aguirre, Carolina Díaz-Pérez, Ainhoa Gutierrez-Cobos, Mónica Sobrado, Estefanía Carabajal, Beatriz del Río, Noelia Ropero, Ramón Villagrasa, José Vivancos, Francisco Sanchez-Madrid, Arantzazu Alfranca
Publikováno v:
Clinical Immunology Communications, Vol 3, Iss , Pp 6-13 (2023)
We analyzed immune response to SARS-CoV-2 vaccination by measuring specific IgG titers and T-cell reactivity to different SARS-CoV-2 peptides in multiple sclerosis patients taking different disease-modifying treatments. Of the 88 patients included, 7
Externí odkaz:
https://doaj.org/article/a3a5627a595c47c39adcb26af5fd23be
Oxidative stress induces loss of pericyte coverage and vascular instability in PGC-1α-deficient mice
Autor:
Ignacio Prieto, Alberto Tierrez, Juan Miguel Redondo, Nieves García-Quintans, Elvira Arza, Cristina Sánchez-Ramos, Arántzazu Alfranca, María Monsalve
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α) is a regulator of mitochondrial oxidative metabolism and reactive oxygen species (ROS) homeostasis that is known to be inactivated in diabetic subjects. This study aimed to inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb08611c14c9de5608f29743c6ab1087
https://doi.org/10.1007/s10456-016-9502-0
https://doi.org/10.1007/s10456-016-9502-0
Autor:
Juan Miguel Redondo, Arántzazu Alfranca, Angel L. Armesilla, Amelia Escolano, Nerea Méndez-Barbero, Mara Martín-Alonso, Miguel R. Campanero, Alicia G. Arroyo, Noelia Lozano-Vidal, Jorge Oller, Silvia Villahoz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
et al.
Emerging evidence indicates that the metalloproteinase Adamts-1 plays a significant role in the pathophysiology of vessel remodeling, but little is known about the signaling pathways that control Adamts-1 expression. We show that vascular
Emerging evidence indicates that the metalloproteinase Adamts-1 plays a significant role in the pathophysiology of vessel remodeling, but little is known about the signaling pathways that control Adamts-1 expression. We show that vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2634dd7dd5143bd45b2e57fa262f37d8
https://doi.org/10.1128/mcb.00494-15
https://doi.org/10.1128/mcb.00494-15
Autor:
Farjana B. Rowther, Elizabeth J. Cartwright, Juan Miguel Redondo, Weiguang Wang, Delvac Oceandy, Dolores López-Maderuelo, Arántzazu Alfranca, James Brown, Jorge Oller, RR Baggott, Sathishkumar Kurusamy, Beatriz C. Ornes, Amelia Escolano, Ludwig Neyses, Tamer M.A. Mohamed, Angel L. Armesilla, Sara Martínez-Martínez, Pablo Gómez-del Arco
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34:2310-2320
Objective— Vascular endothelial growth factor (VEGF) has been identified as a crucial regulator of physiological and pathological angiogenesis. Among the intracellular signaling pathways triggered by VEGF, activation of the calcineurin/nuclear fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063e61ebb95a1d0132e5f13ada8462e6
https://doi.org/10.1161/atvbaha.114.304363
https://doi.org/10.1161/atvbaha.114.304363
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tertiary lymphoid structures (TLSs) are clusters of lymphoid cells with an organization that resembles that of secondary lymphoid organs. Both structures share common developmental characteristics, although TLSs usually appear in chronically inflamed
Externí odkaz:
https://doaj.org/article/1a7f7734707543a3a7379c054a2df769
Autor:
Luis M. Vilá, Xavier León, Sonia Alcolea, Mercedes Camacho, Francesc Xavier Avilés-Jurado, Rosa Antón, Juan-Miguel Redondo, Marta Soler, Arántzazu Alfranca, Miquel Quer
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 4, Pp 630-642 (2012)
Prostaglandin (PG)E(2) is relevant in tumor biology, and interactions between tumor and stroma cells dramatically influence tumor progression. We tested the hypothesis that cross-talk between head and neck squamous cell carcinoma (HNSCC) cells and fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8399a289a82c0cfd29a8f09a14ed7025
http://www.sciencedirect.com/science/article/pii/S0022227520405577
http://www.sciencedirect.com/science/article/pii/S0022227520405577
Autor:
Sara Martínez-Martínez, Antonio Rodríguez, Inmaculada Soto Ortega, Juan Miguel Redondo, Amelia Escolano, Katia Urso, Arántzazu Alfranca
Publikováno v:
Blood. 118:795-803
The nuclear factor of activated T cells (NFAT) family of transcription factors plays important roles in many biologic processes, including the development and function of the immune and vascular systems. Cells usually express more than one NFAT membe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a816c70432439fbddc6d3aa79036c2c
https://doi.org/10.1182/blood-2010-12-322701
https://doi.org/10.1182/blood-2010-12-322701